Article
Nanoscience & Nanotechnology
Armaghan Fakhfouri, Melanie Colditz, Citsabehsan Devendran, Kateryna Ivanova, Stefan Jacob, Adrian Neild, Andreas Winkler
Summary: Precise manipulation of (sub)-micron particles is crucial in many biomedical applications, and surface acoustic waves (SAW) show great promise for this purpose. In commonly used SAW tweezers, particle manipulation relies on the direct acoustic radiation effect, which becomes less effective for nanoscale particles due to the dominance of a second-order mechanism called acoustic streaming. By utilizing stiff microchannels and precise control, we introduce an approach that combines acoustic streaming with the acoustic radiation effect, resulting in enhanced manipulation of nanoparticles even at relatively large wavelengths.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Optics
Rui Ma, Lian-gang Zhang, Y. Zeng, Gui-dong Liu, Ling-ling Wang, Qi Lin
Summary: We investigated the enhanced optical force in acoustic graphene plasmon (AGP) cavities with ultra-small mode volumes. The AGP mode provides stronger field confinement and higher momentum, thus allowing for giant optical force without polarization preference. We demonstrated high trapping potential and force applied on polystyrene nanoparticles in AGP cavities, with values of -13.6 x 10(2) kBT/mW and 2.5 nN/mW, respectively. The effect of rounded corners and gap distance of AGP cavities on optical force was studied, and the results show that larger radius of rounded corners leads to smaller trapping potential and force provided by AGP cavities. Our findings open up new possibilities for studying optical field and force through acoustic plasmon mode.
Article
Acoustics
Adli Hasan Abu Bakar, Mathew Legg, Daniel Konings, Fakhrul Alam
Summary: The stiffness of wood can be estimated from the acoustic velocity in the longitudinal direction. However, measurements obtained using time-of-flight acoustic velocity are overestimated compared to other methods. This study investigates the phenomenon and shows that dispersion is the cause of the overestimation. Dispersion compensation can mitigate the problem, but further research is needed to explore other techniques.
Article
Chemistry, Physical
N. S. Satpathi, K. N. Nampoothiri, A. K. Sen
Summary: This study investigates the effects of surface wettability, droplet size, impact velocity, and SAW power on the dynamics of droplet impact. The interplay between capillary and viscous forces, inertia forces, and SAW-induced bulk acoustic streaming is found to be the underlying mechanism. The findings provide a deeper understanding of droplet impact on a surface exposed to SAW.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2023)
Article
Biochemical Research Methods
R. M. Trujillo, G. Almanza, D. Sanchez-Saldana, O. Rosand, M. Hoydal, M. Fernandino, C. A. Dorao
Summary: In this work, we demonstrate a reagent-free method for cell lysis of AC16 human cardiomyocyte cells in small volume droplets using high frequency surface acoustic waves. This method provides a valuable alternative for cell lysis in various biological and biomedical applications, particularly for point-of-care platforms.
Article
Engineering, Mechanical
Pengzhan Liu, Huiyu Huang, Xu Wang, Qiang Tang, Xiaomin Qi, Songfei Su, Zongheng Xiang, Junhui Hu
Summary: In this study, an innovative acoustic black hole tweezer (ABHT) is proposed and developed by incorporating a one-dimensional acoustic black hole (ABH) structure. The ABHT can easily achieve multiple manipulation functionalities such as trapping and extraction of particles in various fluidic environments. Numerical simulation and experimental evaluation demonstrate the effectiveness of the ABHT, and the potential of employing ABHs in ultrasonic particle manipulation devices and acoustofluidic devices in the future.
MECHANICAL SYSTEMS AND SIGNAL PROCESSING
(2023)
Article
Physics, Multidisciplinary
Zhuoran Geng, Ilari J. Maasilta
Summary: This work demonstrates that complete tunneling of acoustic waves can occur when leaky surface waves are excited, regardless of the orientations of anisotropic crystals. However, the conditions for achieving complete tunneling have not been explored.
COMMUNICATIONS PHYSICS
(2023)
Article
Optics
Soumendra Nath Bandyopadhyay, Tushar Gaur, Debabrata Goswami
Summary: This study presents a newly developed model to predict the stability of traps in real optical trapping scenarios, which could provide valuable information on the selection of solvents, probes, and optical parameters. The differences between continuous wave and femtosecond pulsed laser mediated optical trapping in terms of scattering and gradient forces in the Rayleigh regime are highlighted.
OPTICS AND LASER TECHNOLOGY
(2021)
Article
Chemistry, Physical
Hemin Pan, Deqing Mei, Chengyao Xu, Xin Li, Yancheng Wang
Summary: In this study, a method for manipulating colloidal multimers using acoustic tweezers with bisymmetric coherent surface acoustic waves (SAWs) was proposed. The shape of the acoustic field can be regulated to achieve contactless modulation of individual colloidal multimers, patterning arrays, and controllable rotation. The technique enables reversible assembly and dynamic manipulation of particles and/or cells in colloid synthesis applications.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2023)
Article
Acoustics
Erlend Magnus Viggen, Havard Kjellmo Arnestad
Summary: This article investigates an enhanced model for sound radiation near and below coincidence. Unlike the classical model, this model fully respects conservation of energy by balancing the radiated power with power lost from the guided wave underlying the vibration. The model successfully validates against exact solutions for leaky A0 Lamb waves around coincidence.
JOURNAL OF SOUND AND VIBRATION
(2023)
Article
Nanoscience & Nanotechnology
Yang Yang, Wei Pang, Hongxiang Zhang, Weiwei Cui, Ke Jin, Chongling Sun, Yanyan Wang, Lin Zhang, Xiubao Ren, Xuexin Duan
Summary: The article introduces a versatile microsystem for observing and analyzing single cells, which can perform various tasks such as observation, pretreatment, and analysis through methods like sound wave triggering and microchannel limitation. The reliability and robustness of this technology in complex biological samples have been demonstrated, indicating its broad potential in various fields.
MICROSYSTEMS & NANOENGINEERING
(2022)
Article
Physics, Applied
Le Liu, Long-Xiang Xie, Weichun Huang, Xiu Juan Zhang, Ming-Hui Lu, Yan-Feng Chen
Summary: Sound absorption is crucial for room acoustics and noise control. Acoustic metamaterials, especially those based on deep learning, show promise in achieving broadband sound absorption. This letter presents a deep learning-based acoustic metamaterial approach that achieves ultra-broadband sound absorption without visible oscillation. Results from numerical simulations and experiments demonstrate the effectiveness and versatility of this approach.
APPLIED PHYSICS LETTERS
(2022)
Article
Chemistry, Analytical
Muhammad Musoddiq Jaafar, Mohd Farhanulhakim Mohd Razip Wee, Hoang-Tan-Ngoc Nguyen, Le Trung Hieu, Rahul Rai, Ashish Kumar Sahoo, Chang Fu Dee, Edward Yi Chang, Burhanuddin Yeop Majlis, Clarence Augustine T. H. Tee
Summary: This study investigated the effect of a titanium/gold guiding layer on the surface acoustic wave propagation of GaN/sapphire substrate. It was found that the guiding layer could transform the propagation modes, act as a sensing layer for biomolecule binding, and influence the output signal in terms of frequency or velocity. The GaN/sapphire device integrated with a guiding layer could potentially be used as a biosensor and in wireless telecommunication applications.
Article
Chemistry, Multidisciplinary
A. Sudeepthi, A. Nath, L. Y. Yeo, A. K. Sen
Summary: This study investigates the coalescence of droplets in a two-phase system in microwells driven by surface acoustic waves (SAWs) and elucidates the physics behind the phenomenon through a scaling analysis of relevant forces. The influence of input SAW power and droplet size on film drainage time is explored, and criteria for the onset of coalescence are derived. The study demonstrates the possibility of driving concurrent coalescence of multiple droplets, with potential applications in demulsification and sample/reagent mixing within microwells for biochemical assays.
Article
Materials Science, Multidisciplinary
Sheng Zhang, Yang Wang, Manzhu Ke, Fengming Liu, Hailong He, Liping Ye, Zhengyou Liu
Summary: Metafluids, a version of metamaterials with fluid background, have been found to accommodate a third parameter, the effective shearlike modulus. The experimental implementation of this novel metafluid, capable of supporting surface waves, updates the existing knowledge of surface waves.
Article
Nanoscience & Nanotechnology
Citsabehsan Devendran, David J. Collins, Adrian Neild
Summary: Surface acoustic wave (SAW) micromanipulation offers modularity, easy integration into microfluidic devices and a high degree of flexibility. However, reducing the threshold for manipulating smaller particles is a major challenge. The novel excitation configuration based on diffractive-acoustic SAW (DASAW) actuation shows promise in reducing the critical minimum particle size that can be manipulated, with the ability to tune the streaming magnitude by changing the channel height.
MICROFLUIDICS AND NANOFLUIDICS
(2022)
Article
Chemistry, Analytical
Li Liang, Xuejia Hu, Yang Shi, Shukun Zhao, Qinghao Hu, Minhui Liang, Ye Ai
Summary: This paper introduces a novel optofluidic method for fabricating tunable liquid microlens arrays (MLAs) and demonstrates their ability to achieve tunable focusing and high-quality imaging. The focal length of the MLAs can be adjusted by changing the refractive index of the liquid droplets, showing promising opportunities for various applications.
ANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
William Sean Harley, Kirill Kolesnik, Mingxin Xu, Daniel Edward Heath, David John Collins
Summary: This work demonstrates a method to generate designed and highly localized acoustic fields using 3D resonant mass-spring microstructures, enabling rapid and spatially defined controllable micromanipulation. This sub-wavelength, 3D acoustofluidic approach has potential applications in sample preparation, cell analysis, and diagnostics.
ADVANCED FUNCTIONAL MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Mingxin Xu, William S. Harley, Zhichao Ma, Peter V. S. Lee, David J. Collins
Summary: Acoustic metasurfaces with complex 3D structures complicate their fabrication and applicability to higher frequencies, but an ultrathin metasurface approach utilizing planarized micropillars in a discretized phase array is demonstrated here. This subwavelength metasurface can be easily produced via a single-step etching process and is suitable for megahertz-scale applications. The flexibility of this approach is further demonstrated in the production of complex acoustic patterns via acoustic holography. This metasurface approach, combined with predictive models, has broad potential for robust, high-frequency acoustic manipulation in various applications.
ADVANCED MATERIALS
(2023)
Article
Biochemical Research Methods
Bryan Ang, Ankush Sookram, Citsabehsan Devendran, Vincent He, Kellie Tuck, Victor Cadarso, Adrian Neild
Summary: Surface acoustic wave (SAW) driven devices often use polymeric microfluidic channels with low acoustic impedance mismatch to the fluid in contact for precise control of the wave field. This work demonstrates the successful implementation of integrating a glass insert at the ceiling of the PDMS microfluidic channel in a SAW activated nanosieve, resulting in a significant increase in flow rate and maintenance of high capture efficiencies. The glass-inserted device allows for processing larger volume samples, overcoming a main limitation of these devices.
Article
Chemistry, Analytical
Bryan Ang, Ruhollah Habibi, Ciaren Kett, Wai Hoe Chin, Kellie L. Tuck, Adrian Neild, Victor J. Cadarso
Summary: Microfluidic concentration technology can detect low concentrations of bacteria in samples, making it suitable for time-sensitive situations such as clinical settings and food quality control. By using a packed bed of micro-particles activated by surface acoustic waves, bacteria can be efficiently captured and recovered for further analysis.
SENSORS AND ACTUATORS B-CHEMICAL
(2023)
Article
Biophysics
Minhui Liang, Qiang Tang, Jianwei Zhong, Ye Ai
Summary: Microfluidics provides a powerful platform for biological analysis by precisely manipulating fluids and microparticles. The imaging and impedance cell analyzer (IM2Cell) introduced here combines single cell level impedance analysis and hydrodynamic mechanical phenotyping, demonstrating multi-stress level mechanical phenotyping capabilities. IM2Cell can characterize cell diameter, deformability responses, and electrical properties, providing high-dimensional information about subcellular components. It has been validated for different cell lines and shows potential for deformability studies of PBMC subpopulations.
BIOSENSORS & BIOELECTRONICS
(2023)
Article
Chemistry, Physical
Jianwei Zhong, Minhui Liang, Ye Ai
Summary: Co-encapsulation of bead carriers and biological cells in microfluidics has become a powerful technique for various biological assays in single-cell genomics and drug screening. However, current co-encapsulation approaches limit the effective throughput due to a trade-off between cell/bead pairing rate and probability of multiple cells in individual droplets. The DUPLETS system is reported to overcome this problem by differentiating the encapsulated content in individual droplets and sorting out targeted droplets via a combined screening of mechanical and electrical characteristics.
Article
Engineering, Biomedical
Jianwei Zhong, Minhui Liang, Qiang Tang, Ye Ai
Summary: By introducing a label-free selectable cell quantity encapsulation in droplets sorting system, the purity and throughput of single-cell droplets can be improved. This system combines electrical impedance based screening with biocompatible acoustic sorting to achieve high efficiency and throughput while removing multi-cells and empty droplets.
MATERIALS TODAY BIO
(2023)
Article
Chemistry, Physical
Vincent He, Victor J. Cadarso, Susanne Seibt, Ben J. Boyd, Adrian Neild
Summary: In this study, a microfluidic approach was used to prepare different aqueous and lipid droplets and induce phase transformations in the liquid medium. The results showed that when the lipid droplets and aqueous droplets coalesced, distinct structures with different compositions formed on the two sides of the merged droplet. Through diffusion limited interface, water molecules gradually hydrated the lipid portion, leading to a series of phase transformations. This study provides a new approach for studying the kinetics of phase transformations and identifying non-equilibrium phases in droplet-based lyotropic liquid systems.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2023)
Article
Chemistry, Multidisciplinary
Jiahong Chen, Jianwei Zhong, Yifu Chang, Yinning Zhou, Seok Hwee Koo, Thean Yen Tan, Hongtao Lei, Ye Ai
Summary: Antimicrobial resistance is a serious threat to global public health. A label-free electrical impedance-based microfluidic platform has been designed to expedite and streamline antimicrobial susceptibility testing (AST) for clinical practice, with a rapid 2-minute AST assay at the single-bacterium level. This platform enables accurate analysis of bacterial viability and determination of antimicrobial resistance.
Article
Chemistry, Analytical
Kirill Kolesnik, Daniel Quang Le Pham, Jessica Fong, David John Collins
Summary: Researchers have found that a particle focusing spot in the center of a rotating fluid is formed by the secondary flow. The rotational velocity and the shape of the vessel significantly influence the particle's equilibrium position. This study demonstrates the formation of a single focusing spot in the center of the vessel and the repeatable formation of stable ring-shaped particle arrangements.
Article
Biochemical Research Methods
Kirill Kolesnik, Philipp Segeritz, Daniel J. Scott, Vijay Rajagopal, David J. Collins
Summary: Acoustofluidic devices can manipulate particles and cells in arbitrary configurations at the microscale without complex patterning. This approach is enabling for cell studies and tissue engineering applications.
Article
Biochemical Research Methods
Jiahong Chen, Jianwei Zhong, Hongtao Lei, Ye Ai
Summary: This study presents a novel microfluidic electrical impedance-based multidimensional single-bacterium profiling system that can detect bacteria in a wide concentration range and accurately differentiate their viability and gram types. The system utilizes multi-frequency impedance quantification to analyze the size, concentration, and membrane impedance of bacteria in a single flow-through interrogation. The system has been demonstrated to have a wide bacterial counting range and can rapidly and accurately discriminate the viability and gram types of bacteria in a label-free manner.
Article
Biochemical Research Methods
Junyang Gai, Citsabehsan Devendran, Adrian Neild, Reza Nosrati
Summary: By using an acoustic streaming device, the study investigated the rheotaxis behavior of sperm in microchannels and found that changes in flow velocity could affect the trajectory of sperm.
