Antimicrobial, antibiofilm, and microbial barrier properties of poly (ε-caprolactone)/cloisite 30B thin films

Development of antibacterial and antibiofilm surfaces is in high demand. In this study, nanocomposite of Poly (epsilon-caprolactone)/Cloisite 30B was prepared by the solvent casting method. The membranes were characterised by SEM, AFM, and FTIR. Evaluation of water uptake, antimicrobial, antibiofilm, and microbial barrier properties demonstrated a significant antimicrobial and antibiofilm activity against MTCC strain of Staphylococcus haemolyticus and strong biofilm positive Staphylococcus epidermidis of clinical origin at low clay concentrations. These membranes acted as an excellent barrier to the penetration of microorganism. These nanocomposites can have promising applications in various fields including packaging.