The Role of ACTH and Corticosteroids for Sepsis and Septic Shock: An Update

The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)

(2016) Mervyn Singer et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Adrenocortical endocrine disruption

(2016) Philip W. Harvey   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Systemic Corticosteroids and Transition to Delirium in Critically Ill Patients*

(2015) Annemiek E. Wolters et al.   CRITICAL CARE MEDICINE

Targeting the annexin 1-formyl peptide receptor 2/ALX pathway affords protection against bacterial LPS-induced pathologic changes in the murine adrenal cortex

(2015) Nicholas A. P. S. Buss et al.   FASEB JOURNAL

Glucocorticosteroids for sepsis: systematic review with meta-analysis and trial sequential analysis

(2015) M. Volbeda et al.   INTENSIVE CARE MEDICINE

Cognitive decline after sepsis

(2015) Djillali Annane et al.   Lancet Respiratory Medicine

Hypothalamic-pituitary-adrenal axis in lethal canine Staphylococcus aureus pneumonia

(2014) Irene Cortés-Puch et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Interleukin-1β induced activation of the hypothalamus–pituitary–adrenal axis is dependent on interleukin-1 receptors on non-hematopoietic cells

(2014) Takashi Matsuwaki et al.   BRAIN BEHAVIOR AND IMMUNITY

Corticosteroids and Transition to Delirium in Patients With Acute Lung Injury*

(2014) Matthew P. Schreiber et al.   CRITICAL CARE MEDICINE

Adrenocortical Scavenger Receptor Class B Type I Deficiency Exacerbates Endotoxic Shock and Precipitates Sepsis-Induced Mortality in Mice

(2014) Sophie Gilibert et al.   JOURNAL OF IMMUNOLOGY

Surviving Sepsis Campaign: International Guidelines for Management of Severe Sepsis and Septic Shock, 2012

(2013) R. P. Dellinger et al.   INTENSIVE CARE MEDICINE

Glucocorticoid-induced skeletal muscle atrophy

(2013) O. Schakman et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Imaging in sepsis-associated encephalopathy—insights and opportunities

(2013) Daniel J. Stubbs et al.   Nature Reviews Neurology

Reduced Cortisol Metabolism during Critical Illness

(2013) Eva Boonen et al.   NEW ENGLAND JOURNAL OF MEDICINE

Hypothalamo-pituitary and immune-dependent adrenal regulation during systemic inflammation

(2013) Waldemar Kanczkowski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gluco- and mineralocorticoid biological effects of a 7-day treatment with low doses of hydrocortisone and fludrocortisone in septic shock

(2012) Bruno Laviolle et al.   INTENSIVE CARE MEDICINE

Endothelial glucocorticoid receptor is required for protection against sepsis

(2012) J. E. Goodwin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

R2: The Absence of Adrenal Gland Enlargement during Septic Shock Predicts Mortality

(2011) Boris Jung et al.   ANESTHESIOLOGY

Glucocorticoid receptor dimerization is required for survival in septic shock via suppression of interleukin-1 in macrophages

(2011) Anna Kleiman et al.   FASEB JOURNAL

Low-dose steroids for septic shock and severe sepsis: the use of Bayesian statistics to resolve clinical trial controversies

(2011) Andre C. Kalil et al.   INTENSIVE CARE MEDICINE

Hydrocortisone Enhances the Function of the Blood-Nerve Barrier Through the Up-Regulation of Claudin-5

(2011) Yoko Kashiwamura et al.   NEUROCHEMICAL RESEARCH

Changes in CRH and ACTH Synthesis during Experimental and Human Septic Shock

(2011) Andrea Polito et al.   PLoS One

Corticosteroids for severe sepsis: an evidence-based guide for physicians

(2011) Djillali Annane   Annals of Intensive Care

The Effects of Opioids and Opioid Analogs on Animal and Human Endocrine Systems

(2010) Cassidy Vuong et al.   ENDOCRINE REVIEWS

Human and experimental septic shock are characterized by depletion of lipid droplets in the adrenals

(2010) Andrea Polito et al.   INTENSIVE CARE MEDICINE

Corticosteroid Treatment and Intensive Insulin Therapy for Septic Shock in Adults

(2010)   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Long-term Cognitive Impairment and Functional Disability Among Survivors of Severe Sepsis

(2010) Theodore J. Iwashyna et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Effects of hydrocortisone on microcirculatory alterations in patients with septic shock*

(2009) Gustavo Luiz Büchele et al.   CRITICAL CARE MEDICINE

Predisposing Factors for Adrenal Insufficiency

(2009) Stefan R. Bornstein   NEW ENGLAND JOURNAL OF MEDICINE

LOW-DOSE DEXAMETHASONE-SUPPLEMENTED FLUID RESUSCITATION REVERSES ENDOTOXIN-INDUCED ACUTE RENAL FAILURE AND PREVENTS CORTICAL MICROVASCULAR HYPOXIA

(2009) Tanja Johannes et al.   SHOCK

Modulation of glucocorticoid receptor expression, inflammation, and cell apoptosis in septic guinea pig lungs using methylprednisolone

(2008) Koki Kamiyama et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Systemic Immune Challenge Activates an Intrinsically Regulated Local Inflammatory Circuit in the Adrenal Gland

(2008) Linda Engström et al.   ENDOCRINOLOGY

SR-BI protects against endotoxemia in mice through its roles in glucocorticoid production and hepatic clearance

(2008) Lei Cai et al.   JOURNAL OF CLINICAL INVESTIGATION

Differential effects of hydrocortisone and TNFα on tight junction proteins in anin vitromodel of the human blood-brain barrier

(2008) Carola Förster et al.   JOURNAL OF PHYSIOLOGY-LONDON

From inflammation to sickness and depression: when the immune system subjugates the brain

(2007) Robert Dantzer et al.   NATURE REVIEWS NEUROSCIENCE