Article
Medicine, General & Internal
Matteo Lambertini, Claudia Massarotti, Julie Havas, Barbara Pistilli, Anne-Laure Martin, Alexandra Jacquet, Charles Coutant, Florence Coussy, Asma Dhaini Merimeche, Florence Lerebours, Christine Rousset-Jablonski, Christelle Jouannaud, Olivier Rigal, Marion Fournier, Patrick Soulie, Maria Alice Franzoi, Lucia Del Mastro, Ann H. Partridge, Fabrice Andre, Ines Vaz-Luis, Antonio Di Meglio
Summary: As life expectancy increases for cancer patients, survivorship has become a crucial aspect of breast cancer care. Adequate contraceptive counseling is important for premenopausal breast cancer patients who do not wish to become pregnant. This study examined contraceptive use and methods in early breast cancer patients and identified factors associated with contraceptive use over time. The findings highlight the importance of raising awareness and providing targeted contraceptive counseling for premenopausal women with early breast cancer.
Article
Oncology
Rikke Norgaard Pedersen, Lene Mellemkjaer, Bent Ejlertsen, Mette Norgaard, Deirdre P. Cronin-Fenton
Summary: Patients with late breast cancer recurrence have a more favorable prognosis compared to those with early recurrence, and the localization of recurrent disease is the main prognostic factor for breast cancer death.
JOURNAL OF CLINICAL ONCOLOGY
(2022)
Article
Medicine, General & Internal
Anne Dorte Lerche Helgestad, Mette Bach Larsen, Sisse Njor, Mette Tranberg, Lone Kjeld Petersen, Berit Andersen
Summary: This study aims to improve the participation rate by offering cervical cancer and colorectal cancer screening during breast cancer screening. Participants will be randomly assigned and the intervention effect will be evaluated through a survey questionnaire. The primary outcomes will assess the difference in coverage of CCU and CRC screening between the intervention and control group.
Article
Oncology
Lien van Walle, Didier Verhoeven, Lorenza Marotti, Antonio Ponti, Mariano Tomatis, Isabel T. Rubio
Summary: This study utilized the EUSOMA database to analyze data from 56 certified breast centers, revealing significant variations and trends in breast cancer treatment across Europe, demonstrating important differences.
EUROPEAN JOURNAL OF CANCER
(2023)
Article
Oncology
Fatima Cardoso, Amelia McCartney, Antonio Ponti, Lorenza Marotti, Conny Vrieling, Alexandru Eniu, Berta Sousa, Carla Ripamonti, Luzia Travado, Sabine Spitz, Eva Jolly, Giuseppe Curigliano, Frederique Penault-Llorca, Frederic Lecouvet, Isabel T. Rubio, Laura Biganzoli
Summary: The European Society of Breast Cancer Specialists and the Advanced Breast Cancer Global Alliance have developed the first set of quality indicators for metastatic breast cancer (MBC) with the aim of ensuring high-quality care and adherence to guidelines in breast cancer centers.
EUROPEAN JOURNAL OF CANCER
(2023)
Article
Oncology
Igor L. Gomes-Santos, Zohreh Amoozgar, Ashwin S. Kumar, William W. Ho, Kangsan Roh, Nilesh P. Talele, Hannah Curtis, Kosuke Kawaguchi, Rakesh K. Jain, Dai Fukumura
Summary: Exercise training can delay tumor growth, increase vascular normalization, and enhance CD8(+) T-cell infiltration, playing an important role in breast cancer treatment.
CANCER IMMUNOLOGY RESEARCH
(2021)
Article
Oncology
Elise Dumas, Lucie Laot, Florence Coussy, Beatriz Grandal Rejo, Eric Daoud, Enora Laas, Amyn Kassara, Alena Majdling, Rayan Kabirian, Floriane Jochum, Paul Gougis, Sophie Michel, Sophie Houzard, Christine Le Bihan-Benjamin, Philippe-Jean Bousquet, Judicael Hotton, Chloe-Agathe Azencott, Fabien Reyal, Anne-Sophie Hamy
Summary: This study aimed to create a national cohort of French women diagnosed with early-stage breast cancer in order to promote cancer research and improve understanding of breast cancer. By aggregating and annotating administrative healthcare data, the study provides detailed descriptions and longitudinal trends of treatment pathways, adverse effects, care consumption, and basic characteristics of breast cancer patients.
Article
Oncology
Lindsay J. Collin, Deirdre P. Cronin-Fenton, Thomas P. Ahern, Michael Goodman, Lauren E. McCullough, Lance A. Waller, Anders Kjaersgaard, Per Damkier, Peer M. Christiansen, Bent Ejlertsen, Maj-Britt Jensen, Henrik Toft Sorensen, Timothy L. Lash
Summary: This study evaluated the association between early discontinuation of endocrine therapy and breast cancer recurrence in premenopausal women. The results showed a higher rate of recurrence in women who discontinued endocrine therapy compared to those who completed the recommended treatment. These findings emphasize the importance of clinical follow-up and behavioral interventions to support the persistence of adjuvant endocrine therapy in preventing breast cancer recurrence.
CLINICAL CANCER RESEARCH
(2021)
Article
Multidisciplinary Sciences
Giovanna Chiorino, Elisabetta Petracci, Emir Sehovic, Ilaria Gregnanin, Elisa Camussi, Maurizia Mello-Grand, Paola Ostano, Emilia Riggi, Viviana Vergini, Alessia Russo, Enrico Berrino, Andrea Ortale, Francesca Garena, Tiziana Venesio, Federica Gallo, Elisabetta Favettini, Alfonso Frigerio, Giuseppe Matullo, Nereo Segnan, Livia Giordano
Summary: The objective of this study was to identify circulating microRNA (miRs) ratios associated with breast cancer (BC) in women attending mammography screening. By using small-RNA sequencing and RT-qPCR techniques, the study identified 7 miR ratios associated with BC, as well as non-molecular factors such as body mass index, menopausal status, lifestyle, and breast density. The resulting model achieved an ROC AUC of 0.79, with a sensitivity and specificity of 71.9% and 76.6%, respectively. This is the first study report circulating miRs for BC detection in a screening setting.
SCIENTIFIC REPORTS
(2023)
Article
Genetics & Heredity
Naomi J. Wilcox, Martine Dumont, Anna Gonzalez-Neira, Sara Carvalho, Charles Joly Beauparlant, Marco Crotti, Craig Luccarini, Penny Soucy, Stephane Dubois, Rocio K. Nunez-Torres, Guillermo E. Pita, Eugene Gardner, Joe Dennis, M. Rosario Alonso, Nuria alvarez, Caroline Baynes, Annie Claude Collin-Deschesnes, Sylvie Desjardins, Heiko Becher, Sabine Behrens, Manjeet Bolla, Jose Castelao, Jenny Chang-Claude, Sten Cornelissen, Thilo Doerk, Christoph Engel, Manuela Gago-Dominguez, Pascal Guenel, Andreas Hadjisavvas, Eric Hahnen, Mikael Hartman, Belen Herraez, Marion Kiechle, Jingmei A. SGBCC Investigators, Audrey Jung, Renske Keeman, Jingmei I. Li, Maria Loizidou, Michael Lush, Kyriaki P. Michailidou, Mihalis E. Panayiotidis, Xueling Sim, Soo Hwang Teo, Jonathan Tyrer, Lizet van der Kolk, Cecilia K. Wahlstrom, Qin K. Wang, John R. B. Perry, Javier Benitez, Marjanka M. Schmidt, Rita Schmutzler, Paul D. P. Pharoah, Arnaud F. Droit, Alison Dunning, Anders Kvist, Peter Devilee, Douglas Easton, Jacques Simard
Summary: A meta-analysis of three large whole-exome sequencing datasets revealed associations between protein-truncating and rare missense variants in several genes, including ATM, BRCA1, BRCA2, and MAP3K1, with breast cancer susceptibility. Additionally, associations were found for LZTR1, ATR, BARD1, and CDKN2A.
Article
Radiology, Nuclear Medicine & Medical Imaging
Soyeoun Kim, Thi Xuan Mai Tran, Huiyeon Song, Seungho Ryu, Yoosoo Chang, Boyoung Park
Summary: This study investigated the risk of breast cancer associated with the combination of mammographic density and benign breast disease in Korean women. The results showed that women with both high breast density and benign breast disease had an elevated risk of developing breast cancer.
Article
Surgery
Takaaki Konishi, Michimasa Fujiogi, Daisuke Shigemi, Hiroki Matsui, Kiyohide Fushimi, Masahiko Tanabe, Yasuyuki Seto, Hideo Yasunaga
Summary: This study identified several risk factors for postoperative bleeding in breast cancer surgery, such as high body mass index, anemia, cardiovascular diseases, liver diseases, psychoses, preoperative heparin use, and surgical procedures.
WORLD JOURNAL OF SURGERY
(2022)
Review
Oncology
Michelle M. Kim, Minesh P. Mehta, DeeDee K. Smart, Patricia S. Steeg, Julie A. Hong, Michael G. Espey, Pataje G. Prasanna, Laura Crandon, Christine Hodgdon, Niki Kozak, Terri S. Armstrong, Aki Morikawa, Nicole Willmarth, Kirk Tanner, Adrienne Boire, Melanie Hayden Gephart, Kim A. Margolin, Jona Hattangadi-Gluth, Hussein Tawbi, Daniel M. Trifiletti, Caroline Chung, Upal Basu-Roy, Robyn Burns, Isabella C. Glitza Oliva, Ayal A. Aizer, Carey K. Anders, Joanne Davis, Manmeet S. Ahluwalia, Veronica Chiang, Jing Li, Rupesh Kotecha, Silvia C. Formenti, Benjamin M. Ellingson, Vinai Gondi, Paul W. Sperduto, Jill S. Barnholtz-Sloan, Jordi Rodon, Eudocia Q. Lee, Mustafa Khasraw, Debra Nana Yeboa, Priscilla K. Brastianos, Evanthia Galanis, C. Norman Coleman, Mansoor M. Ahmed
Summary: Brain metastases are a global public health concern with increasing importance. Stakeholders gathered in a virtual workshop to define research priorities and address unmet needs for patients, aiming to achieve meaningful advances in patient outcomes. This Policy Review provides an overview of existing knowledge gaps, collaborative opportunities, and specific recommendations for future directions in brain metastases research. Enhanced coordination and the active engagement of patients and advocates are crucial for major advances in research.
Article
Public, Environmental & Occupational Health
Yin Jin, Wang Junren, Jiang Jingwen, Sun Yajing, Chen Xi, Qin Ke
Summary: This paper conducts an in-depth research on the construction method and application of breast cancer-specific database system based on full data lifecycle, aiming to support the application of data in clinical practices, scientific research, and teaching, and fully tap the value of medical big data.
FRONTIERS IN PUBLIC HEALTH
(2021)
Article
Oncology
Virginia Lope, Angel Guerrero-Zotano, Emma Ruiz-Moreno, Begona Bermejo, Silvia Antolin, Alvaro Montano, Jose Manuel Baena-Canada, Manuel Ramos Vazquez, Nerea Fernandez de Larrea-Baz, Jose Ignacio Chacon, Jose Angel Garcia-Saenz, Clara Olier, Montserrat Munoz, Antonio Anton, Pedro Sanchez Rovira, Angels Arcusa Lanza, Sonia Gonzalez, Amparo Oltra, Joan Brunet, Joaquin Gavila Gregori, Maria Teresa Martinez, Lourdes Calvo, Libertad Rosell, Susana Bezares, Roberto Pastor-Barriuso, Beatriz Perez-Gomez, Miguel Martin, Marina Pollan
Summary: The study found that compliance with cancer prevention recommendations among breast cancer survivors is generally low, particularly in terms of limiting consumption of red/processed meats and high fiber intake. Compliance is worse among women with higher education levels and those with first-degree relatives with breast cancer. This information is helpful for designing personalized preventive measures.