Patent cliff and strategic switch: exploring strategic design possibilities in the pharmaceutical industry

The Evolving Drug Development Landscape: From Blockbusters to Niche Busters in the Orphan Drug Space

(2014) Ashish Kumar Kakkar et al.   DRUG DEVELOPMENT RESEARCH

Secondary Patenting Of Branded Pharmaceuticals: A Case Study Of How Patents On Two HIV Drugs Could Be Extended For Decades

(2013) Tahir Amin et al.   HEALTH AFFAIRS

Evergreening, patent challenges, and effective market life in pharmaceuticals

(2012) C. Scott Hemphill et al.   JOURNAL OF HEALTH ECONOMICS

Analysing stratified medicine business models and value systems: innovation-regulation interactions

(2012) James Mittra et al.   New Biotechnology

Current trends in the pharmaceutical industry – A case study approach

(2011) Alexandru Rusu et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

The productivity crisis in pharmaceutical R&D

(2011) Fabio Pammolli et al.   NATURE REVIEWS DRUG DISCOVERY

Productivity Shortfalls in Drug Discovery: Contributions from the Preclinical Sciences?

(2010) M. Williams   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Rare diseases, orphan drugs and their regulation: questions and misconceptions

(2010) Erik Tambuyzer   NATURE REVIEWS DRUG DISCOVERY

Can regenerative medicine save Big Pharma’s business model from the patent cliff?

(2010) Alexander Denoon et al.   Regenerative Medicine

Biotech acquisitions by big pharma: why and what is next

(2009) Nafees N. Malik   DRUG DISCOVERY TODAY

Balancing Innovation and Access: Patent Challenges Tip the Scales

(2009) M. J. Higgins et al.   SCIENCE

Impact of Economic, Regulatory, and Patent Policies on Innovation in Cancer Chemoprevention

(2008) H. G. Grabowski et al.   Cancer Prevention Research

Does orphan drug legislation really answer the needs of patients?

(2008) Marlene E Haffner et al.   LANCET