Article
Pediatrics
Sujith S. Pereira, Ajay K. Sinha, Divyen K. Shah, Stephen T. Kempley
Summary: The aim of this study was to determine carotid blood flow volume, a surrogate for cerebral blood flow, using Doppler ultrasound in extremely preterm infants. The results showed that carotid blood flow volume increased significantly during the first three days and was positively correlated with invasive mean arterial blood pressure on day 1. Additionally, carotid blood flow volume was significantly associated with left ventricular output in infants with closing or closed ductus arteriosus on day 1.
Article
Critical Care Medicine
Hongzhi Wang, Wei Chen, Hao Cheng, Can Liu, WeiDong Yao, Fang Ding, YuLong Wang, Yongquan Chen
Summary: This study suggests that corrected flow time in the common carotid artery can predict volume responsiveness under mechanical ventilation, and this predictive performance is not influenced by positive end-expiratory pressure.
Article
Engineering, Biomedical
Hanying Liang, Guochen Ning, Shangqi Dai, Longfei Ma, Jianwen Luo, Xinran Zhang, Hongen Liao
Summary: This paper proposes a spatiotemporal ultrasound reconstruction framework based on freehand sonography. By using a morphology-based phase extraction method and a robust kernel regression model, it enhances the ability to provide dynamic structure information without radiation. The experimental results demonstrate the feasibility of the framework and its potential application value in ultrasound examination of dynamic anatomy.
INTERNATIONAL JOURNAL OF COMPUTER ASSISTED RADIOLOGY AND SURGERY
(2022)
Article
Computer Science, Artificial Intelligence
Paulin Paul, B. Priestly Shan
Summary: Carotid Intima Media Thickness (cIMT) is a simple and inexpensive clinical marker used for predicting and assessing future cardio/cerebrovascular diseases. B-mode ultrasound images are the best option for measuring cIMT. However, speckle noise in the ultrasound images can affect the clarity of medical details, reducing the accuracy of analysis and diagnosis. This article presents various preprocessing schemes for removing speckle in carotid ultrasound images, highlighting the importance of preprocessing and recent advancements in US imaging.
Article
Computer Science, Information Systems
J. H. Gagan, Harshit S. Shirsat, Grissel P. Mathias, B. Vaibhav Mallya, Jasbon Andrade, K. Rajagopal, J. R. Harish Kumar
Summary: We propose a method based on basis splines for accurate segmentation of lumen boundary and media adventitia boundary in B-mode ultrasound images. The method utilizes gradient descent and Green's theorem for energy minimization and further optimization. Experimental results demonstrate the effectiveness of the method in terms of accuracy and Dice index.
Article
Acoustics
Gerhard Michael von Reutern, Fabienne Perren, Ilona Alpsoy, Jens Allendoerfer
Summary: This study suggests that the measurement of the distal lumen can serve as an additional sonographic criterion for evaluating the degree of carotid stenosis, particularly in cases of very high-grade stenosis. It helps prevent misdiagnosis caused by the high variability of intrastenotic peak systolic velocities.
ULTRASCHALL IN DER MEDIZIN
(2023)
Article
Acoustics
Loes Willems, Jenske Vermeulen, Anouk Wiegerinck, Stein Fekkes, Michel Reijnen, Michiel Warle, Chris Dekorte, Dick Thijssen
Summary: The construct validity and reproducibility of three commonly used handheld ultrasound devices (Telemed MicrUs EXT-1H, Butterfly iQ, and Philips Lumify) in measuring carotid arterial diameter were evaluated. The handheld devices showed excellent construct validity and intra-observer variability. Additionally, good-to-moderate inter-observer variability was observed for the different devices.
ULTRASOUND IN MEDICINE AND BIOLOGY
(2023)
Article
Medicine, General & Internal
Muhammet Bayraktar, Mustafa Kacmaz
Summary: This study found a high correlation between central venous pressure (CVP) and common carotid artery (CCA) diameter, suggesting that measurement of CCA diameter with ultrasound can be used as an alternative, low-cost and noninvasive method for detecting CVP.
Article
Multidisciplinary Sciences
Seok Goo Kim, Ik Joon Jo, Soo Yeon Kang, Jonghoon Yoo, Guntak Lee, Jong Eun Park, Taerim Kim, Sung Yeon Hwang, Won Chul Cha, Tae Gun Shin, Heewon Han, Hee Yoon
Summary: In patients with septic shock, norepinephrine (NE) significantly increased the diameter and blood flow of the common carotid artery (CCA), without altering the peak systolic velocity (PSV).
SCIENTIFIC REPORTS
(2021)
Article
Medicine, General & Internal
Seungho Jung, Jeongmin Kim, Sungwon Na, Won Seok Nam, Do-Hyeong Kim
Summary: In patients under low tidal volume mechanical ventilation, carotid corrected flow time (FTc) can predict fluid responsiveness better than pulse pressure variation (PPV). However, further studies are needed before its clinical use.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Multidisciplinary Sciences
Natalie L. James, Zoran Milijasevic, Anthony Ujhazy, David Huber, Randi Rotne, Glenn Edwards, Kieri Jermyn, David S. Celermajer
Summary: This study confirmed the surgical implantation and biomaterial safety of the Guardian device in 10 sheep, with the device being surrounded by a fibrous capsule over time without any adverse events. The feasibility of surgical implantation and the potential viability of minimally invasive explant were also demonstrated.
Article
Agriculture, Dairy & Animal Science
Marieta K. Sevcikova, Maria Figurova, Karol Sevcik, Marian Hluchy, Michal Domaniza, Maria Lapsanska, Zuzana Drahovska, Zdenek Zert
Summary: This study assessed the physiological values and waveform appearance of carotid arteries in 104 healthy dogs and investigated the correlations between blood velocity and resistive index, body weight and diameter. The study also examined the differences between observers and the influence of sex on the calculations of Doppler parameters. The findings contribute to the understanding of vascular diseases in veterinary medicine that are associated with neurological disorders, thromboembolism, oncologic disease, and arterial stenosis.
Article
Critical Care Medicine
Andrew S. Liteplo, Jessica Schleifer, Keith A. Marill, Calvin K. Huang, Stacey K. Gouker, Daniel Ratanski, Eden Diamond, Michael R. Filbin, Hamid Shokoohi
Summary: The study found that in patients suspected of sepsis, ultrasound measurements of carotid flow time showed significant changes, while carotid blood flow did not. However, these measurements were not predictive of fluid responsiveness, mortality, or the need for intensive care unit admission in the patients.
Article
Critical Care Medicine
Antonio Messina, Mariagiovanna Caporale, Lorenzo Calabro, Giulia Lionetti, Daniele Bono, Guia Margherita Matronola, Andrea Brunati, Luciano Frassanito, Emanuela Morenghi, Massimo Antonelli, Michelle S. Chew, Maurizio Cecconi
Summary: The overall performance of PPV and SVV in predicting fluid responsiveness in the operating room is moderate, approaching an AUC of 0.80 only in some subgroups of surgical patients. The wide grey zone of these dynamic indices should be carefully considered during the assessment of fluid responsiveness. Factors such as high tidal volume and the choice of colloids for fluid challenge may influence the reliability of PPV.
Article
Acoustics
Kun Wang, Zhiyao Li, Yufeng Zhang
Summary: A novel despeckling model IFOTV is proposed for CCA ultrasound images, showing improved performance in suppressing speckle noise and preserving edges, potentially being an alternative to current filters for CCA ultrasound despeckling.
ULTRASONIC IMAGING
(2022)
Article
Medicine, Research & Experimental
Jennifer Gehlen, Sven Klaschik, Claudia Neumann, Mignon-Denise Keyver-Paik, Alexander Mustea, Martin Soehle, Stilla Frede, Markus Velten, Andreas Hoeft, Tobias Hilbert
JOURNAL OF TRANSLATIONAL MEDICINE
(2020)
Article
Anesthesiology
B. Bette, M. Martini, S. Klaschik, T. Hilbert
Article
Medicine, Research & Experimental
Marcel Scheck, Markus Velten, Sven Klaschik, Martin Soehle, Stilla Frede, Jennifer Gehlen, Jochen Hoch, Alexander Mustea, Andreas Hoeft, Tobias Hilbert
Article
Medicine, General & Internal
Claudia Neumann, Markus Velten, Cornelia Heik-Guth, Brigitte Strizek, Maria Wittmann, Tobias Hilbert, Sven Klaschik
Article
Medicine, Research & Experimental
Alexander Kinnen, Sven Klaschik, Claudia Neumann, Eva-Katharina Egger, Alexander Mustea, Martin Soehle, Stilla Frede, Markus Velten, Mark Coburn, Tobias Hilbert
Summary: The study found that ovarian cancer patients received more fluid intraoperatively, with increased expression of genes like IL-8 and MCP-1/CCL2 in their serum. Significant alterations in vascular leakage-related genes were detected in tumor tissue of ovarian cancer patients, and the ANG-2/1 expression ratio was significantly higher in tumor-free peritoneal tissue. Changes in gene expression in peripheral tissues of ovarian cancer patients were associated with postoperative fluid balance.
Article
Anesthesiology
Konrad Peukert, Sven Klaschik, Tobias Hilbert
Article
Biochemistry & Molecular Biology
Jan Menzenbach, Stilla Frede, Janine Petras, Vera Guttenthaler, Andrea Kirfel, Claudia Neumann, Andreas Mayr, Maria Wittmann, Mark Coburn, Sven Klaschik, Tobias Hilbert
Summary: Preoperative serum biomarker profiling with specificity for vascular dysfunction and systemic inflammation was not indicative of subsequent POD development. Surgery-induced systemic inflammation, particularly following cardiac surgery, was associated with POD.
Article
Anesthesiology
Magdalena Sitter, Tobias Schlesinger, Ann-Kristin Reinhold, Axel Scholler, Christian von Heymann, Sabine Welfle, Catharina Bartmann, Achim Woeckel, Stefan Kleinschmidt, Sven Schneider, Andre Gottschalk, Susanne Greve, Julius Z. Wermelt, Roland Wiener, Frank Schulz, Daniel Chappell, Maya Brunner, Claudia Neumann, Patrick Meybohm, Peter Kranke
Summary: This study provides an overview of SARS-CoV-2 positive pregnant women hospitalized for childbirth in Germany and Switzerland during the pandemic. The findings show that the number of pregnant women infected with SARS-CoV-2 at the time of delivery was very low, with most cases presenting as asymptomatic or mild, but also demonstrating the potential for severe progression even in young healthy patients.
Article
Anesthesiology
Claudia Neumann, Tamara Babasiz, Nadine Strassberger-Nerschbach, Ehrenfried Schindler, Christian Reuter, Leonie Weinhold, Maria Wittmann, Tobias Hilbert, Sven Klaschik
Summary: This study aimed to evaluate the validity of the Newborn Infant Parasympathetic Evaluation (NIPE) index in assessing nociception during anesthesia in children below 2 years. The results showed that the NIPE index was more reliable than heart rate in indicating nociception. However, its impact on postoperative outcome remains unclear.
PEDIATRIC ANESTHESIA
(2022)
Article
Orthopedics
Alina Yurutkina, Sven Klaschik, Pascal Kowark, Annette Gass, Carolina Link, Thomas Martin Randau, Jorge Jimenez-Cruz, Mark Coburn, Tobias Hilbert
Summary: This study retrospectively analyzed the comparison of analgesic methods in patients undergoing hip and knee arthroplasty. The results showed that after hip arthroplasty, WPD PCA provided better pain relief and patient comfort, while after knee arthroplasty, Pir PCA provided superior analgesia and a lower complication rate.
JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH
(2022)
Article
Multidisciplinary Sciences
Marcus Thudium, Stefan Moestl, Fabian Hoffmann, Alex Hoff, Evgeniya Kornilov, Karsten Heusser, Jens Tank, Martin Soehle
Summary: Recently, cerebral autoregulation indices based on dynamic correlation indices have been introduced to evaluate cerebral blood flow. However, these indices may have limitations in assessing cerebral autoregulation as indicated by Mx. Further studies are needed to improve the accuracy of these indices.
Article
Neurosciences
Motaz Hamed, Tim Lampmann, Abdallah Salemdawod, Harun Asoglu, Naomi Houedjissin, Marcus Thudium, Lakghomi Asadeh, Frederic Carsten Schmeel, Fabiane Schuch, Hartmut Vatter, Mohammed Banat
Summary: Chronic subdural hematoma (cSDH) is a common disease in the neurological and neurosurgical world. The recommended treatment for cSDH patients with moderate or severe neurological symptoms is surgical evacuation, but cSDH frequently recurs. The patient's ABO blood type may influence the outcome.
Article
Medicine, General & Internal
Claudia Neumann, Lena Gehlen, Leonie Weinhold, Nadine Strassberger-Nerschbach, Martin Soehle, Evgeniya Kornilov, Marcus Thudium
Summary: This study aimed to investigate the use of the nociception level index (NOL) to determine the effect of regional anesthesia in hip or knee arthroplasty patients undergoing general anesthesia with additional peripheral nerve block. The results showed that intraoperative NOL changes may indicate regional anesthesia effectiveness and could be associated with postoperative pain levels.
MEDICINA-LITHUANIA
(2023)
Article
Medicine, General & Internal
Evgeniya Kornilov, Lena Gehlen, Dana Yacobi, Martin Soehle, Ana Kowark, Marcus Thudium
Summary: The objective of this observational cohort study was to investigate the pupillary pain index (PPI) as a method to evaluate sensory areas during joint replacement surgery. The results showed that perioperative PPI was associated with postoperative pain, suggesting that preoperative PPI may be used to predict postoperative pain.
MEDICINA-LITHUANIA
(2023)
Article
Medicine, Research & Experimental
Eva Katharina Egger, Natascha Kohls, Matthias B. Stope, Mateja Condic, Mignon-Denise Keyver-Paik, Dominique Koensgen, Tobias Hilbert, Sven Klaschik, Daniel Exner, Tim Vilz, Alexander Mustea