Tumor necrosis factor links chronic obstructive pulmonary disease and K-ras mutant lung cancer through induction of an immunosuppressive pro-tumor microenvironment

IL6 Blockade Reprograms the Lung Tumor Microenvironment to Limit the Development and Progression of K-ras-Mutant Lung Cancer

(2016) M. S. Caetano et al.   CANCER RESEARCH

Lung Cancer in Patients with Chronic Obstructive Pulmonary Disease. Development and Validation of the COPD Lung Cancer Screening Score

(2015) Juan P. de-Torres et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

MDSC and TGF  Are Required for Facilitation of Tumor Growth in the Lungs of Mice Exposed to Carbon Nanotubes

(2015) A. A. Shvedova et al.   CANCER RESEARCH

Integrating RAS Status into Prognostic Signatures for Adenocarcinomas of the Lung

(2015) M. H. Starmans et al.   CLINICAL CANCER RESEARCH

Systemic Monocytic-MDSCs Are Generated from Monocytes and Correlate with Disease Progression in Breast Cancer Patients

(2015) Caroline Bergenfelz et al.   PLoS One

Neutralization of Tumor Necrosis Factor Bioactivity Ameliorates Urethane-Induced Pulmonary Oncogenesis in Mice

(2015) Sophia P. Karabela et al.   NEOPLASIA

A comparative study of matrix remodeling in chronic models for COPD; mechanistic insights into the role of TNF-α

(2014) Irene M. J. Eurlings et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Cancer statistics, 2014

(2014) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

ER Stress Cooperates with Hypernutrition to Trigger TNF-Dependent Spontaneous HCC Development

(2014) Hayato Nakagawa et al.   CANCER CELL

Proinflammatory S100 Proteins Regulate the Accumulation of Myeloid-Derived Suppressor Cells

(2014) P. Sinha et al.   JOURNAL OF IMMUNOLOGY

Cross-talk among myeloid-derived suppressor cells, macrophages, and tumor cells impacts the inflammatory milieu of solid tumors

(2014) Daniel W. Beury et al.   JOURNAL OF LEUKOCYTE BIOLOGY

T helper 17 cells play a critical pathogenic role in lung cancer

(2014) S. H. Chang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of Myeloid Cell Subsets in Murine Lungs Using Flow Cytometry

(2013) Rinat Zaynagetdinov et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Tumor Necrosis Factor-α Blocks Differentiation and Enhances Suppressive Activity of Immature Myeloid Cells during Chronic Inflammation

(2013) Moshe Sade-Feldman et al.   IMMUNITY

Transmembrane TNF-  Promotes Suppressive Activities of Myeloid-Derived Suppressor Cells via TNFR2

(2013) X. Hu et al.   JOURNAL OF IMMUNOLOGY

Tumor associated macrophages in relapsed and refractory Hodgkin lymphoma

(2013) Carla Casulo et al.   LEUKEMIA RESEARCH

Differential effects of smoking and COPD upon circulating myeloid derived suppressor cells

(2013) Sergio Scrimini et al.   RESPIRATORY MEDICINE

TNF signaling drives myeloid-derived suppressor cell accumulation

(2012) Xueqiang Zhao et al.   JOURNAL OF CLINICAL INVESTIGATION

Inflammatory cytokines in cancer: tumour necrosis factor and interleukin 6 take the stage

(2011) S. I. Grivennikov et al.   ANNALS OF THE RHEUMATIC DISEASES

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

NF-kappaB in Lung Tumorigenesis

(2011) Zhenjian Cai et al.   Cancers

Interleukin 6, but Not T Helper 2 Cytokines, Promotes Lung Carcinogenesis

(2010) C. E. Ochoa et al.   Cancer Prevention Research

NF-kappaB in lung cancer, a carcinogenesis mediator and a prevention and therapy target

(2010) Wenshu Chen   Frontiers in Bioscience-Landmark

Curcumin inhibits COPD-like airway inflammation and lung cancer progression in mice

(2009) S.J. Moghaddam et al.   CARCINOGENESIS

Myeloid-Derived Suppressor Cells: Linking Inflammation and Cancer

(2009) S. Ostrand-Rosenberg et al.   JOURNAL OF IMMUNOLOGY

Promotion of Lung Carcinogenesis by Chronic Obstructive Pulmonary Disease–Like Airway Inflammation in a K-ras–Induced Mouse Model

(2008) Seyed Javad Moghaddam et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Stat3 mediates myeloid cell–dependent tumor angiogenesis in mice

(2008) Maciej Kujawski et al.   JOURNAL OF CLINICAL INVESTIGATION

Cancer-related inflammation

(2008) Alberto Mantovani et al.   NATURE

Lung Cancer

(2008) Roy S. Herbst et al.   NEW ENGLAND JOURNAL OF MEDICINE

Haemophilus influenzae Lysate Induces Aspects of the Chronic Obstructive Pulmonary Disease Phenotype

(2007) Seyed Javad Moghaddam et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY