Review
Dentistry, Oral Surgery & Medicine
Diogo Cruz, Francisca Monteiro, Maria Paco, Manuel Vaz-Silva, Carolina Lemos, Miguel Alves-Ferreira, Teresa Pinho
Summary: This systematic review examines the genetic overlap between temporomandibular disorders (TMD) and primary headache disorders (PHD), identifying COMT and ESR1 genes as important factors in both conditions, while the impact of the MTHFR gene remains uncertain. The study highlights the importance of understanding the role of ESR1 and COMT genes in pain pathogenesis and their potential as therapeutic targets.
JAPANESE DENTAL SCIENCE REVIEW
(2022)
Article
Medicine, General & Internal
Jong-Ho Kim, Yeonkyeong Lee, Young-Suk Kwon, Jong-Hee Sohn
Summary: Migraine and non-migraine headaches (nMH) are associated with increased risks of gastrointestinal (GI) and respiratory disorders, including asthma, bronchitis, and gastroesophageal reflux disorder. This study investigated the relationship between pulmonary microbes and brain disorders, suggesting that the lung-brain axis is involved in this association. After analyzing clinical data from over 11 years, it was found that patients with migraine had significantly higher odds ratios for various GI disorders compared to controls, while patients with nMH had higher odds ratios for asthma and bronchitis.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Biochemistry & Molecular Biology
Marta Waliszewska-Prosol, Marta Nowakowska-Kotas, Justyna Chojdak-Lukasiewicz, Slawomir Budrewicz
Summary: Migraine and sleep disorders are common chronic diseases with significant negative impacts on society and economy. The association between them is observed but not fully understood, with recent progress in understanding common anatomical structures and pathogenetic mechanisms. Better understanding of these mechanisms in the future will expand treatment options.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Biochemistry & Molecular Biology
Orr Shahar, Alexander Botvinnik, Noam Esh-Zuntz, Michal Brownstien, Rachel Wolf, Amit Lotan, Gilly Wolf, Bernard Lerer, Tzuri Lifschytz
Summary: There is growing interest in the therapeutic potential of psilocybin. This study examined the role of different serotonergic receptors and TAAR1 in modulating the head twitch response induced by 5-HTP and psilocybin in mice. The findings suggest that compounds that modulate psychedelic-induced head twitch response may have important therapeutic potential.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Health Care Sciences & Services
Malek Zihlif, Amer Imraish, Baeth Al-Rawashdeh, Aya Qteish, Raihan Husami, Rawand Husami, Farah Tahboub, Yazun Jarrar, Su-Jun Lee
Summary: This study found a statistically significant association between multiple ADAM33 genetic polymorphisms and IgE levels, particularly showing a significant relationship between V4 polymorphism and IgE levels in both adults and children. Such findings add to the growing evidence that the ADAM33 gene has a major impact on IgE levels among asthmatic patients of Jordanian origin.
JOURNAL OF PERSONALIZED MEDICINE
(2021)
Article
Multidisciplinary Sciences
Osama Y. Alshogran, Laith N. Al-Eitan, Shoroq M. Altawalbeh, Hatem A. Aman
Summary: This study investigated the genetic association of dopamine D4 receptor and serotonin transporter genes with psychiatric symptom susceptibility among hemodialysis patients. The findings suggest that certain genetic polymorphisms may be linked to anxiety symptoms in this patient population.
Article
Immunology
Minghang Pei, Xinshu Liu, Peizeng Yang, Chan Zhao, Fei Gao, Yi Qu, Anyi Liang, Junyan Xiao, Meifen Zhang
Summary: IL33/ST2 gene polymorphisms are associated with the development of BDU, with specific alleles showing significant differences in BD patients with different clinical features, indicating the important role of IL33/ST2 in the pathogenesis of BDU.
FRONTIERS IN IMMUNOLOGY
(2021)
Article
Clinical Neurology
Yen-Feng Wang, Yi-Chu Liao, Yi-Shiang Tzeng, Shih-Pin Chen, Jiing-Feng Lirng, Jong-Ling Fuh, Wei-Ta Chen, Kuan-Lin Lai, Yi-Chung Lee, Shuu-Jiun Wang
Summary: The NOTCH3 p.R544C variant is not associated with the risk or clinical manifestations of migraine. However, patients with the p.R544C variant are less likely to have pulsatile headaches and more likely to have white matter damage in the external capsule and anterior temporal lobe.
Review
Dentistry, Oral Surgery & Medicine
Jessica Conti Reus, Helena Polmann, Beatriz Dulcineia Mendes Souza, Carlos Flores-Mir, Daniela Aparecida Godoi Goncalves, Luiz Paulo de Queiroz, Jeffrey Okeson, Graziela De Luca Canto
Summary: This systematic review examined the association between primary headaches (PHs) and temporomandibular disorders (TMDs) in adults. The study found a positive association between painful TMD and tension-type headache, migraines, and chronic headaches. However, no positive association was found between painless articular TMDs and tension-type headache or migraines. The certainty of evidence for the results varied between very low and low.
JOURNAL OF THE AMERICAN DENTAL ASSOCIATION
(2022)
Article
Plant Sciences
Le Gao, Chengsheng Meng, Tengfei Yi, Ke Xu, Huiwen Cao, Shuhua Zhang, Xueju Yang, Yong Zhao
Summary: The study identified 270 significant SNPs associated with yield- and quality-related traits in wheat, and detected 638 putative candidate genes near these SNPs. This provides new insights into the genetic basis of wheat yield and quality.
Article
Clinical Neurology
Gudrun Gossrau, Marie Frost, Anna Klimova, Thea Koch, Rainer Sabatowski, Coralie Mignot, Antje Haehner
Summary: This study investigated the relationship between sensitivity to olfactory stimuli and the clinical course of migraine. The results showed that patients with longer migraine duration and higher migraine-related impairment demonstrated increased sensitivity to odors during preictal, ictal, and interictal phases.
JOURNAL OF HEADACHE AND PAIN
(2022)
Article
Clinical Neurology
Cherubino Di Lorenzo, Giorgio Di Lorenzo, Gianluca Coppola, Vincenzo Parisi, Gaetano S. Grieco, Filippo Maria Santorelli, Esterina Pascale, Francesco Pierelli
Summary: This study found a similar prevalence of the Wolframin His611Arg polymorphism among MOH, EM, and HS groups, with the R/R genotype associated with increased symptomatic drug consumption in MOH patients, especially combination drugs.
FRONTIERS IN NEUROLOGY
(2021)
Article
Medicine, General & Internal
Hee-Jin Im, Yoo-Ha Hong, Soo-Jin Cho
Summary: Neck pain is a common symptom among migraine patients, and its impact on headaches and contributing factors are unclear. This study aimed to investigate the disability caused by neck pain on headaches and factors linked to comorbid neck pain, including sleep-related variables. The study found that neck pain was present in 51.9% of migraine patients, with high disability observed in some patients. Factors such as medication days per month, severe disability of migraine, and excessive daytime sleepiness were significant predictors for the severe impact of headaches. The study also found a positive correlation between neck pain and higher monthly headache days, female gender, and likelihood of obstructive sleep apnea among migraine patients.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Medicine, General & Internal
Alessandra Voci, Oliviero Bruni, Michela Ada Noris Ferilli, Laura Papetti, Samuela Tarantino, Fabiana Ursitti, Giorgia Sforza, Federico Vigevano, Luigi Mazzone, Massimiliano Valeriani, Romina Moavero
Summary: The study revealed a high prevalence of sleep disorders in pediatric migraine, which were associated with higher headache severity and poorer response to acute therapy.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Obstetrics & Gynecology
Benedetta Pasquini, Viola Seravalli, Silvia Vannuccini, Francesco La Torre, Pierangelo Geppetti, Luigi Iannone, Silvia Benemei, Felice Petraglia
Summary: In women with endometriosis, many experience headache, and about 53.4% of them are diagnosed with migraine. Among these, 18.6% have pure menstrual migraine, 45.7% have menstrually related migraine, and 35.7% have non-menstrual migraine. Patients with endometriosis and migraine are more likely to have dysmenorrhea and dysuria compared to those without migraine.
REPRODUCTIVE BIOMEDICINE ONLINE
(2023)
Article
Neurosciences
Sefer Varol, Hasan Huseyin Ozdemir, Esref Akil, Demet Arslan, M. Ufuk Aluclu, Caner F. Demir, Yavuz Yucel
ARQUIVOS DE NEURO-PSIQUIATRIA
(2015)
Article
Genetics & Heredity
Salih Coskun, Lokman Ustyol, Yasemin Bayram, M. Selcuk Bektas, Suleyman Gulsen, Abdullah Cim, Unal Uluca, Didem Savas
Article
Endocrinology & Metabolism
Abdullah Cim, Salih Coskun, Orhan Gorukmez, Hatice Yuksel, Unal Uluca, Erminia Di Pietro, Francois Plourde, Nancy Elise Braverman
JOURNAL OF CLINICAL RESEARCH IN PEDIATRIC ENDOCRINOLOGY
(2015)
Article
Behavioral Sciences
Seref Simsek, Ihsan Cetin, Abdullah Cim, Savas Kaya
Article
Genetics & Heredity
Salih Coskun, Seref Simsek, Mehmet Akif Camkurt, Abdullah Cim, Sercan Bulut Celik
Article
Clinical Neurology
Seref Simsek, Tugba Yuksel, Abdullah Cim, Savas Kaya
INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
(2016)
Article
Pediatrics
Seref Simsek, Veli Yildirim, Abdullah Cim, Savas Kaya
JOURNAL OF CHILD AND ADOLESCENT PSYCHOPHARMACOLOGY
(2016)
Article
Primary Health Care
Ahmet Yilmaz, Muharrem Ak, Abdullah Cim, Yilmaz Palanci, Faruk Kilinc
EUROPEAN JOURNAL OF GENERAL PRACTICE
(2016)
Article
Clinical Neurology
Mohamed Sheikh Hassan, Yavuz Yucel
Summary: Central neurocytomas are rare neuroepithelial tumors that can cause increased intracranial pressure, with the exact etiology remaining unclear.
TURKISH JOURNAL OF NEUROLOGY
(2021)
Article
Health Care Sciences & Services
Mohamed Sheikh Hassan, Yavuz Yucel
Summary: This study investigates factors influencing the early hospital arrival of acute ischemic stroke patients in Mogadishu, Somalia. Factors contributing to delays include long travel distance, non-ambulance transportation, living alone, lack of recognition of stroke symptoms, night-time stroke onset, lack of knowledge about thrombolytic treatment, and non-hemiplegic presentation. Improving these modifiable factors through public education can prevent delays in hospital arrival and improve outcomes for stroke patients.
JOURNAL OF MULTIDISCIPLINARY HEALTHCARE
(2022)
Article
Clinical Neurology
Salih Coskun, Sefer Varol, Hasan H. Ozdemir, Sercan Bulut Celik, Metin Balduz, Mehmet Akif Camkurt, Abdullah Cim, Demet Arslan, Mehmet Ugur Cevik
NEUROPSYCHIATRIC DISEASE AND TREATMENT
(2016)
Article
Genetics & Heredity
Salih Coskun, Yavuz Yucel, Abdullah Cim, Beyhan Cengiz, Serdar Oztuzcu, Sefer Varol, Hasan H. Ozdemir, Ertugrul Uzar
JOURNAL OF GENETICS
(2016)
