Angiogenic inhibitors delivered by the type III secretion system of tumor-targeting Salmonella typhimurium safely shrink tumors in mice

Combined prokaryotic–eukaryotic delivery and expression of therapeutic factors through a primed autocatalytic positive-feedback loop

(2016) Lei Shi et al.   JOURNAL OF CONTROLLED RELEASE

Genetically modified "obligate" anaerobic Salmonella typhimurium as a therapeutic strategy for neuroblastoma

(2015) Zhu-Ling Guo et al.   Journal of Hematology & Oncology

Therapeutic efficacy of tumor-targeting Salmonella typhimurium A1-R on human colorectal cancer liver metastasis in orthotopic nude-mouse models

(2015) Takashi Murakami et al.   Oncotarget

Targeted deletion of thearaoperon ofSalmonella typhimuriumenhances L-arabinose accumulation and drives PBAD-promoted expression of anti-cancer toxins and imaging agents

(2014) Hyun Hong et al.   CELL CYCLE

Salmonella Secreted Factor L Deubiquitinase of Salmonella typhimurium Inhibits NF- B, Suppresses I B  Ubiquitination and Modulates Innate Immune Responses

(2014) G. Le Negrate et al.   JOURNAL OF IMMUNOLOGY

Engineering of bacterial strains and their products for cancer therapy

(2013) Nuno Bernardes et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Comparison of efficacy ofSalmonella typhimuriumA1-R and chemotherapy on stem-like and non-stem human pancreatic cancer cells

(2013) Yukihiko Hiroshima et al.   CELL CYCLE

PCA-1/ALKBH3 Contributes to Pancreatic Cancer by Supporting Apoptotic Resistance and Angiogenesis

(2012) I. Yamato et al.   CANCER RESEARCH

Hypoxia upregulates CD147 through a combined effect of HIF-1α and Sp1 to promote glycolysis and tumor progression in epithelial solid tumors

(2012) Xia Ke et al.   CARCINOGENESIS

The tumor microenvironment in hepatocellular carcinoma (Review)

(2012) Massimo Libra   INTERNATIONAL JOURNAL OF ONCOLOGY

Explicit hypoxia targeting with tumor suppression by creating an “obligate” anaerobic Salmonella Typhimurium strain

(2012) Bin Yu et al.   Scientific Reports

Environmental conditioning in the control of macrophage thrombospondin-1 production

(2012) Jezrom B. Fordham et al.   Scientific Reports

Engineering bacteria toward tumor targeting for cancer treatment: current state and perspectives

(2011) Che-Hsin Lee   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Immune microenvironments in solid tumors: new targets for therapy

(2011) S. L. Shiao et al.   GENES & DEVELOPMENT

Proteomic Screening of Anaerobically Regulated Promoters fromSalmonellaand Its Antitumor Applications

(2011) Jianxiang Chen et al.   MOLECULAR & CELLULAR PROTEOMICS

Tumor angiogenesis: molecular pathways and therapeutic targets

(2011) Sara M Weis et al.   NATURE MEDICINE

Antitumor therapeutic effects of a genetically engineered Salmonella typhimurium harboring TNF-α in mice

(2010) Won Suck Yoon et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Salmonella as Live Trojan Horse for Vaccine Development and Cancer Gene Therapy

(2010) Maria Moreno et al.   CURRENT GENE THERAPY

Bifidobacterium longum as a delivery system of TRAIL and endostatin cooperates with chemotherapeutic drugs to inhibit hypoxic tumor growth

(2009) B Hu et al.   CANCER GENE THERAPY

Oral delivery of tumor-targetingSalmonellaexhibits promising therapeutic efficacy and low toxicity

(2009) Guo Chen et al.   CANCER SCIENCE

Attenuated Salmonella Targets Prodrug Activating Enzyme Carboxypeptidase G2 to Mouse Melanoma and Human Breast and Colon Carcinomas for Effective Suicide Gene Therapy

(2008) F. Friedlos et al.   CLINICAL CANCER RESEARCH