Sphingosine kinase 1 inhibition improves lipopolysaccharide/D-galactosamine-induced acute liver failure by inhibiting mitogen-activated protein kinases pathway

Abstract B09: Sphingosine kinase 1 (SPHK1) is a novel mediator of tumor-stroma interaction in ovarian cancer

(2015) Jessica A. Beach et al.   CANCER RESEARCH

Inhibition of sphingosine kinase 1 ameliorates acute liver failure by reducing high-mobility group box 1 cytoplasmic translocation in liver cells

(2015) Yan-Chang Lei   WORLD JOURNAL OF GASTROENTEROLOGY

Emodin ameliorated lipopolysaccharide-induced fulminant hepatic failure by blockade of TLR4/MD2 complex expression in D-galactosamine-sensitized mice

(2014) Xinru Yin et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Sphingosine-1-phosphate receptor 1 reporter mice reveal receptor activation sites in vivo

(2014) Mari Kono et al.   JOURNAL OF CLINICAL INVESTIGATION

Sphingosine-1-Phosphate and Its Receptors: Structure, Signaling, and Influence

(2013) Hugh Rosen et al.   Annual Review of Biochemistry

Hepatopoietin Cn reduces ethanol-induced hepatoxicity via sphingosine kinase 1 and sphingosine 1-phosphate receptors

(2013) Yang Liu et al.   JOURNAL OF PATHOLOGY

Sphingosine kinase-1 mediates endotoxemia-induced hyperinflammation in aged animals

(2013) MARIA LUFRANO et al.   Molecular Medicine Reports

Acute Liver Failure

(2013) William Bernal et al.   NEW ENGLAND JOURNAL OF MEDICINE

Sphingosine-1–Phosphate Receptor–3 Is a Novel Biomarker in Acute Lung Injury

(2012) Xiaoguang Sun et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

The Role of Sphingosine Kinase 1 in Patients With Severe Acute Pancreatitis

(2012) Qiurong Li et al.   ANNALS OF SURGERY

Eukaryotic elongation factor 2 controls TNF-α translation in LPS-induced hepatitis

(2012) Bárbara González-Terán et al.   JOURNAL OF CLINICAL INVESTIGATION

Inhibition of Sphingosine 1-Phosphate Receptor 2 Protects against Renal Ischemia-Reperfusion Injury

(2011) S. Won Park et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Sphingosine kinase 1 protects against renal ischemia–reperfusion injury in mice by sphingosine-1-phosphate1 receptor activation

(2011) Sang Won Park et al.   KIDNEY INTERNATIONAL

Pathological roles of MAPK signaling pathways in human diseases

(2010) Eun Kyung Kim et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Protective effects of Asiaticoside on acute liver injury induced by lipopolysaccharide/D-galactosamine in mice

(2010) Li Zhang et al.   PHYTOMEDICINE

Inhibition of the MAP kinase ERK protects from lipopolysaccharide-induced lung injury

(2009) Katrin Schuh et al.   BIOCHEMICAL PHARMACOLOGY

Induction of Hepatitis by JNK-Mediated Expression of TNF-α

(2009) Madhumita Das et al.   CELL

Synthesis and Evaluation of Sphingosine Analogues as Inhibitors of Sphingosine Kinases

(2009) Lingkai Wong et al.   JOURNAL OF MEDICINAL CHEMISTRY

Sphingosine kinase 1 regulates the expression of proinflammatory cytokines and nitric oxide in activated microglia

(2009) D. Nayak et al.   NEUROSCIENCE

Inhalation of sphingosine kinase inhibitor attenuates airway inflammation in asthmatic mouse model

(2008) Teruaki Nishiuma et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Activation of Sphingosine Kinase-1 Reverses the Increase in Lung Vascular Permeability Through Sphingosine-1-Phosphate Receptor Signaling in Endothelial Cells

(2008) Mohammad Tauseef et al.   CIRCULATION RESEARCH

TLR4 and S1P receptors cooperate to enhance inflammatory cytokine production in human gingival epithelial cells

(2008) Mehmet A. Eskan et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The importance of immune dysfunction in determining outcome in acute liver failure

(2008) Charalambos Gustav Antoniades et al.   JOURNAL OF HEPATOLOGY

Dendritic cell PAR1–S1P3 signalling couples coagulation and inflammation

(2008) Frank Niessen et al.   NATURE

Dual and distinct roles for sphingosine kinase 1 and sphingosine 1 phosphate in the response to inflammatory stimuli in RAW macrophages

(2007) Samar M. Hammad et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS