Inhaled corticosteroids and the increased risk of pneumonia: what’s new? A 2015 updated review

Corticosteroid Therapy for Patients Hospitalized With Community-Acquired Pneumonia

(2015) Reed A.C. Siemieniuk et al.   ANNALS OF INTERNAL MEDICINE

Discontinuation of Inhaled Corticosteroids in COPD and the Risk Reduction of Pneumonia

(2015) Samy Suissa et al.   CHEST

Prevention of Acute Exacerbations of COPD

(2015) Gerard J. Criner et al.   CHEST

Role of infection in exacerbations of chronic obstructive pulmonary disease

(2015) Marc Miravitlles et al.   CURRENT OPINION IN PULMONARY MEDICINE

Effect of Corticosteroids on Treatment Failure Among Hospitalized Patients With Severe Community-Acquired Pneumonia and High Inflammatory Response

(2015) Antoni Torres et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Adjunct prednisone therapy for patients with community-acquired pneumonia: a multicentre, double-blind, randomised, placebo-controlled trial

(2015) Claudine Angela Blum et al.   LANCET

Effect of roflumilast on exacerbations in patients with severe chronic obstructive pulmonary disease uncontrolled by combination therapy (REACT): a multicentre randomised controlled trial

(2015) Fernando J Martinez et al.   LANCET

P123 Inhaled corticosteroid plus long-acting β2-agonist therapy is overused in the treatment of patients with chronic obstructive pulmonary disease: post hoc analyses of two 1-year studies: Abstract P123 Table 1

(2015) H Watz et al.   THORAX

Blood eosinophil counts, exacerbations, and response to the addition of inhaled fluticasone furoate to vilanterol in patients with chronic obstructive pulmonary disease: a secondary analysis of data from two parallel randomised controlled trials

(2015) Steven Pascoe et al.   Lancet Respiratory Medicine

Use of Inhaled Corticosteroids in Patients With COPD and the Risk of TB and Influenza

(2014) Yaa-Hui Dong et al.   CHEST

INSTEAD: a randomised switch trial of indacaterolversussalmeterol/fluticasone in moderate COPD

(2014) Andrea Rossi et al.   EUROPEAN RESPIRATORY JOURNAL

Low-dose corticosteroid use and mortality in severe community-acquired pneumonia patients

(2014) Takashi Tagami et al.   EUROPEAN RESPIRATORY JOURNAL

Eosinophilic inflammation in COPD: prevalence and clinical characteristics: Table 1–

(2014) Dave Singh et al.   EUROPEAN RESPIRATORY JOURNAL

Inhaled corticosteroids in COPD: the clinical evidence

(2014) Pierre Ernst et al.   EUROPEAN RESPIRATORY JOURNAL

Combination Long-Acting β-Agonists and Inhaled Corticosteroids Compared With Long-Acting β-Agonists Alone in Older Adults With Chronic Obstructive Pulmonary Disease

(2014) Andrea S. Gershon et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Airway Microbiome Dynamics in Exacerbations of Chronic Obstructive Pulmonary Disease

(2014) Y. J. Huang et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Prehospital Use of Inhaled Corticosteroids and Point Prevalence of Pneumonia at the Time of Hospital Admission: Secondary Analysis of a Multicenter Cohort Study

(2014) Emir Festic et al.   MAYO CLINIC PROCEEDINGS

Withdrawal of Inhaled Glucocorticoids and Exacerbations of COPD

(2014) Helgo Magnussen et al.   NEW ENGLAND JOURNAL OF MEDICINE

Risk of Pneumonia with Inhaled Corticosteroid versus Long-Acting Bronchodilator Regimens in Chronic Obstructive Pulmonary Disease: A New-User Cohort Study

(2014) Rachael L. DiSantostefano et al.   PLoS One

Inhaled Corticosteroids Do Not Influence the Early Inflammatory Response and Clinical Presentation of Hospitalized Subjects With COPD Exacerbation

(2014) E. Crisafulli et al.   Respiratory Care

Inhaled corticosteroids and systemic inflammatory response in community-acquired pneumonia: A prospective clinical study

(2014) Miquel Ferrer et al.   RESPIROLOGY

Towards an ecology of the lung: new conceptual models of pulmonary microbiology and pneumonia pathogenesis

(2014) Robert P Dickson et al.   Lancet Respiratory Medicine

Inhaled steroids in COPD: when should they be used?

(2014) Alvar Agusti et al.   Lancet Respiratory Medicine

Influence of Previous Use of Inhaled Corticoids on the Development of Pleural Effusion in Community-acquired Pneumonia

(2013) Jacobo Sellares et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Systemic Inflammatory Pattern of Patients With Community-Acquired Pneumonia With and Without COPD

(2013) Ernesto Crisafulli et al.   CHEST

Pneumonic and Nonpneumonic Exacerbations of COPD

(2013) Arturo Huerta et al.   CHEST

Inhaled Corticosteroids and Risk of Recurrent Pneumonia: A Population-Based, Nested Case-Control Study

(2013) Dean T. Eurich et al.   CLINICAL INFECTIOUS DISEASES

Chronic obstructive pulmonary disease and mortality from pneumonia: meta-analysis

(2013) Y. K. Loke et al.   INTERNATIONAL JOURNAL OF CLINICAL PRACTICE

Combination of budesonide/formoterol more effective than fluticasone/salmeterol in preventing exacerbations in chronic obstructive pulmonary disease: the PATHOS study

(2013) K. Larsson et al.   JOURNAL OF INTERNAL MEDICINE

Overtreatment of COPD with Inhaled Corticosteroids - Implications for Safety and Costs: Cross-Sectional Observational Study

(2013) Patrick White et al.   PLoS One

Efficacy and safety of roflumilast in patients with stable chronic obstructive pulmonary disease: A meta-analysis

(2013) Jun-Hong Yan et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

Inhaled corticosteroids in COPD and the risk of serious pneumonia

(2013) Samy Suissa et al.   THORAX

Pneumonia and pneumonia related mortality in patients with COPD treated with fixed combinations of inhaled corticosteroid and long acting  2 agonist: observational matched cohort study (PATHOS)

(2013) C. Janson et al.   BMJ-British Medical Journal

Inhaled corticosteroid use in patients with chronic obstructive pulmonary disease and the risk of pneumonia: a retrospective claims data analysis

(2013) Barbara Yawn et al.   International Journal of Chronic Obstructive Pulmonary Disease

Once-daily inhaled fluticasone furoate and vilanterol versus vilanterol only for prevention of exacerbations of COPD: two replicate double-blind, parallel-group, randomised controlled trials

(2013) Mark T Dransfield et al.   Lancet Respiratory Medicine

Blood Eosinophils to Direct Corticosteroid Treatment of Exacerbations of Chronic Obstructive Pulmonary Disease

(2012) Mona Bafadhel et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Inhaled corticosteroids and the risk of pneumonia in Medicare patients with COPD

(2012) Julia Thornton Snider et al.   CURRENT MEDICAL RESEARCH AND OPINION

Treatment of COPD by clinical phenotypes: putting old evidence into clinical practice

(2012) Marc Miravitlles et al.   EUROPEAN RESPIRATORY JOURNAL

The Lung Microbiome in Moderate and Severe Chronic Obstructive Pulmonary Disease

(2012) Alexa A. Pragman et al.   PLoS One

Corticosteroids in the Treatment of Community-Acquired Pneumonia in Adults: A Meta-Analysis

(2012) Wei Nie et al.   PLoS One

How far is real life from COPD therapy guidelines? An Italian observational study

(2012) Antonio Corrado et al.   RESPIRATORY MEDICINE

Changes in prevalence and load of airway bacteria using quantitative PCR in stable and exacerbated COPD

(2012) Davinder S Garcha et al.   THORAX

Chronic respiratory disease, inhaled corticosteroids and risk of non-tuberculous mycobacteriosis

(2012) Claire Andréjak et al.   THORAX

Number needed to treat in COPD: exacerbations versus pneumonias

(2012) Samy Suissa   THORAX

Observational Study of Inhaled Corticosteroids on Outcomes for COPD Patients with Pneumonia

(2011) Dennis Chen et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Long-acting fluticasone furoate has a superior pharmacological profile to fluticasone propionate in human respiratory cells

(2011) Christos Rossios et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Impact of inhaled corticosteroid use on outcome in COPD patients admitted with pneumonia

(2011) A. Singanayagam et al.   EUROPEAN RESPIRATORY JOURNAL

Budesonide/formoterol vs. salmeterol/fluticasone in COPD: a systematic review and adjusted indirect comparison of pneumonia in randomised controlled trials

(2011) D. M. G. Halpin et al.   INTERNATIONAL JOURNAL OF CLINICAL PRACTICE

Effect of budesonide/formoterol pMDI on COPD exacerbations: A double-blind, randomized study

(2011) Amir Sharafkhaneh et al.   RESPIRATORY MEDICINE

Increased risk of nontuberculous mycobacterial infection in asthmatic patients using long-term inhaled corticosteroid therapy

(2011) MASAYUKI HOJO et al.   RESPIROLOGY

Chronic Obstructive Pulmonary Disease Phenotypes

(2010) MeiLan K. Han et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Risks of Pneumonia in Patients with Asthma Taking Inhaled Corticosteroids

(2010) Paul M. O'Byrne et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Reported Pneumonia in Patients With COPD

(2010) Peter M.A. Calverley et al.   CHEST

Risk of pneumonia associated with long-term use of inhaled corticosteroids in chronic obstructive pulmonary disease: a critical review and update

(2010) Sonal Singh et al.   CURRENT OPINION IN PULMONARY MEDICINE

Factors associated with inflammatory cytokine patterns in community-acquired pneumonia

(2010) R. Martinez et al.   EUROPEAN RESPIRATORY JOURNAL

Inhaled corticosteroid use is associated with lower mortality for subjects with COPD and hospitalised with pneumonia

(2010) R. Malo de Molina et al.   EUROPEAN RESPIRATORY JOURNAL

Susceptibility to Exacerbation in Chronic Obstructive Pulmonary Disease

(2010) John R. Hurst et al.   NEW ENGLAND JOURNAL OF MEDICINE

Inhaled corticosteroids and risk of pneumonia: evidence for and against the proposed association

(2010) A. Singanayagam et al.   QJM-AN INTERNATIONAL JOURNAL OF MEDICINE

Pneumonia among COPD patients using inhaled corticosteroids and long-acting bronchodilators

(2010) Douglas Mapel et al.   Primary Care Respiratory Journal

Long-term Use of Inhaled Corticosteroids and the Risk of Pneumonia in Chronic Obstructive Pulmonary Disease

(2009) Sonal Singh et al.   ARCHIVES OF INTERNAL MEDICINE

Safety and Efficacy of Combined Long-Acting β-Agonists and Inhaled Corticosteroids vs Long-Acting β-Agonists Monotherapy for Stable COPD

(2009) Gustavo J. Rodrigo et al.   CHEST

Effect of Fluticasone Propionate/Salmeterol (250/50) on COPD Exacerbations and Impact on Patient Outcomes

(2009) Antonio Anzueto et al.   COPD-Journal of Chronic Obstructive Pulmonary Disease

Efficacy and Tolerability of Budesonide/Formoterol in One Hydrofluoroalkane Pressurized Metered-Dose Inhaler in Patients with Chronic Obstructive Pulmonary Disease

(2009) Stephen I. Rennard et al.   DRUGS

Macrophage activation in exacerbated COPD with and without community-acquired pneumonia

(2009) P. Gutierrez et al.   EUROPEAN RESPIRATORY JOURNAL

Inhaled Corticosteroids in Patients With Chronic Obstructive Pulmonary Disease

(2009) Yoon K. Loke   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Budesonide and the risk of pneumonia: a meta-analysis of individual patient data

(2009) Don D Sin et al.   LANCET

The Influence of COPD on Mortality and Severity Scoring in Community-Acquired Pneumonia

(2009) Dominic Snijders et al.   RESPIRATION

Inhaled corticosteroids and risk of pneumonia in newly diagnosed COPD

(2009) Min J. Joo et al.   RESPIRATORY MEDICINE

Efficacy and Safety of Budesonide and Formoterol in One Pressurized Metered-Dose Inhaler in Patients with Moderate to Very Severe Chronic Obstructive Pulmonary Disease

(2008) Donald P Tashkin et al.   DRUGS

New evidence of risk factors for community-acquired pneumonia: a population-based study

(2008) J. Almirall et al.   EUROPEAN RESPIRATORY JOURNAL

Inhaled Corticosteroids in Patients With Stable Chronic Obstructive Pulmonary Disease

(2008) M. Bradley Drummond et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Effect of fluticasone propionate/salmeterol (250/50μg) or salmeterol (50μg) on COPD exacerbations

(2008) Gary T. Ferguson et al.   RESPIRATORY MEDICINE

The Prevention of Chronic Obstructive Pulmonary Disease Exacerbations by Salmeterol/Fluticasone Propionate or Tiotropium Bromide

(2007) Jadwiga A. Wedzicha et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE