FLASH protects ZEB1 from degradation and supports cancer cells' epithelial-to-mesenchymal transition

ZEB1: At the crossroads of epithelial-mesenchymal transition, metastasis and therapy resistance

(2015) Peijing Zhang et al.   CELL CYCLE

Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer

(2015) Xiaofeng Zheng et al.   NATURE

Epithelial-to-mesenchymal transition is not required for lung metastasis but contributes to chemoresistance

(2015) Kari R. Fischer et al.   NATURE

TGFβSignaling in Tumor Initiation, Epithelial-to-Mesenchymal Transition, and Metastasis

(2015) Panagiotis Papageorgis   Journal of Oncology

The ubiquitin ligase Siah is a novel regulator of Zeb1 in breast cancer

(2015) Anna Chen et al.   Oncotarget

Atypical ubiquitin E3 ligase complex Skp1-Pam-Fbxo45 controls the core epithelial-to-mesenchymal transition-inducing transcription factors

(2015) Ming Xu et al.   Oncotarget

Novel Strategies to Enforce an Epithelial Phenotype in Mesenchymal Cells

(2014) A.-M. Dragoi et al.   CANCER RESEARCH

Significance ofCASP8AP2andH2AFZexpression in survival and risk of relapse in children with acute lymphoblastic leukemia

(2014) Rocío Juárez-Velázquez et al.   LEUKEMIA & LYMPHOMA

ATM-mediated stabilization of ZEB1 promotes DNA damage response and radioresistance through CHK1

(2014) Peijing Zhang et al.   NATURE CELL BIOLOGY

Signaling mechanisms of the epithelial-mesenchymal transition

(2014) D. M. Gonzalez et al.   Science Signaling

Hypermethylation of two CpG sites upstream of CASP8AP2 promoter influences gene expression and treatment outcome in childhood acute lymphoblastic leukemia

(2013) Zhi-Gang Li et al.   LEUKEMIA RESEARCH

Silencing of a large microRNA cluster on human chromosome 14q32 in melanoma: biological effects of mir-376a and mir-376c on insulin growth factor 1 receptor

(2012) Liron Zehavi et al.   Molecular Cancer

TGFβ signalling in context

(2012) Joan Massagué   NATURE REVIEWS MOLECULAR CELL BIOLOGY

FLASH Knockdown Sensitizes Cells To Fas-Mediated Apoptosis via Down-Regulation of the Anti-Apoptotic Proteins, MCL-1 and Cflip Short

(2012) Song Chen et al.   PLoS One

Tumor Metastasis: Molecular Insights and Evolving Paradigms

(2011) Scott Valastyan et al.   CELL

Dynamics of adherens junctions in epithelial establishment, maintenance, and remodeling

(2011) Buzz Baum et al.   JOURNAL OF CELL BIOLOGY

PIAS1 interacts with FLASH and enhances its co-activation of c-Myb

(2011) Anne Hege Alm-Kristiansen et al.   Molecular Cancer

E-cadherin, β-catenin, and ZEB1 in malignant progression of cancer

(2009) Otto Schmalhofer et al.   CANCER AND METASTASIS REVIEWS

Epithelial to Mesenchymal Transition Contributes to Drug Resistance in Pancreatic Cancer

(2009) T. Arumugam et al.   CANCER RESEARCH

Interaction of FLASH with Arsenite Resistance Protein 2 Is Involved in Cell Cycle Progression at S Phase

(2009) M. Kiriyama et al.   MOLECULAR AND CELLULAR BIOLOGY

FLASH acts as a co-activator of the transcription factor c-Myb and localizes to active RNA polymerase II foci

(2008) A H Alm-Kristiansen et al.   ONCOGENE