Sharpin promotes hepatocellular carcinoma progression via transactivation of Versican expression

Elevation of SIPL1 (SHARPIN) Increases Breast Cancer Risk

(2015) Jason De Melo et al.   PLoS One

Activation of nuclear factor κB pathway and downstream targets survivin and livin by SHARPIN contributes to the progression and metastasis of prostate cancer

(2014) Yiming Zhang et al.   CANCER

SIPL1-facilitated PTEN ubiquitination contributes to its association with PTEN

(2014) Jason De Melo et al.   CELLULAR SIGNALLING

Frequency of and Predictive Factors for Vascular Invasion after Radiofrequency Ablation for Hepatocellular Carcinoma

(2014) Yoshinari Asaoka et al.   PLoS One

HOIP Deficiency Causes Embryonic Lethality by Aberrant TNFR1-Mediated Endothelial Cell Death

(2014) Nieves Peltzer et al.   Cell Reports

Forkhead box Q1 promotes hepatocellular carcinoma metastasis by transactivating ZEB2 and VersicanV1 expression

(2013) Limin Xia et al.   HEPATOLOGY

Versican 3′-untranslated region (3′-UTR) functions as a ceRNA in inducing the development of hepatocellular carcinoma by regulating miRNA activity

(2012) Ling Fang et al.   FASEB JOURNAL

Comparison of resection and ablation for hepatocellular carcinoma: A cohort study based on a Japanese nationwide survey

(2012) Kiyoshi Hasegawa et al.   JOURNAL OF HEPATOLOGY

STING Specifies IRF3 Phosphorylation by TBK1 in the Cytosolic DNA Signaling Pathway

(2012) Y. Tanaka et al.   Science Signaling

SHARPIN is a component of the NF-κB-activating linear ubiquitin chain assembly complex

(2011) Fuminori Tokunaga et al.   NATURE

SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis

(2011) Fumiyo Ikeda et al.   NATURE

Linear ubiquitination prevents inflammation and regulates immune signalling

(2011) Björn Gerlach et al.   NATURE

SHARPIN is an endogenous inhibitor of β1-integrin activation

(2011) Juha K. Rantala et al.   NATURE CELL BIOLOGY

Shank-interacting protein–like 1 promotes tumorigenesis via PTEN inhibition in human tumor cells

(2010) Lizhi He et al.   JOURNAL OF CLINICAL INVESTIGATION

Newly identified tumor-associated role of human Sharpin

(2010) Jinyoung Jung et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Sipl1 and Rbck1 Are Novel Eya1-Binding Proteins with a Role in Craniofacial Development

(2010) K. Landgraf et al.   MOLECULAR AND CELLULAR BIOLOGY

The biological role and regulation of versican levels in cancer

(2009) Carmela Ricciardelli et al.   CANCER AND METASTASIS REVIEWS

Structure and Regulation of the Versican Promoter

(2009) Clelia Domenzain-Reyna et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Carcinoma-produced factors activate myeloid cells through TLR2 to stimulate metastasis

(2009) Sunhwa Kim et al.   NATURE

Involvement of linear polyubiquitylation of NEMO in NF-κB activation

(2009) Fuminori Tokunaga et al.   NATURE CELL BIOLOGY