Thrombin Cleavage of Osteopontin Modulates Its Activities in Human CellsIn Vitroand Mouse Experimental Autoimmune EncephalomyelitisIn Vivo

The Role of Osteopontin in Neurodegenerative Diseases

(2018) Miryam Carecchio et al.   JOURNAL OF ALZHEIMERS DISEASE

Osteopontin promotes the progression of gastric cancer through the NF-κB pathway regulated by the MAPK and PI3K

(2014) JIE LIU et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Increased Osteopontin Expression in Dendritic Cells Amplifies IL-17 Production by CD4+ T Cells in Experimental Autoimmune Encephalomyelitis and in Multiple Sclerosis

(2014) G. Murugaiyan et al.   JOURNAL OF IMMUNOLOGY

Subcutaneous inverse vaccination with PLGA particles loaded with a MOG peptide and IL-10 decreases the severity of experimental autoimmune encephalomyelitis

(2014) Giuseppe Cappellano et al.   VACCINE

Expression and localization of osteopontin, homing cell adhesion molecule/CD44, and integrin αvβ3 in mucoepidermoid carcinoma and acinic cell adenocarcinoma of salivary gland origin

(2014) T.C. Fok et al.   Oral Surgery Oral Medicine Oral Pathology Oral Radiology

Endothelial Cell Tube Formation Assay for the In Vitro Study of Angiogenesis

(2014) Katie L. DeCicco-Skinner et al.   Jove-Journal of Visualized Experiments

Early detection of thrombin activity in neuroinflammatory disease

(2013) Dimitrios Davalos et al.   ANNALS OF NEUROLOGY

Differential induction of IL-17, IL-10, and IL-9 in human T helper cells by B7h and B7.1

(2013) Riccardo Mesturini et al.   CYTOKINE

The Impact of Osteopontin Gene Variations on Multiple Sclerosis Development and Progression

(2012) Cristoforo Comi et al.   Clinical & Developmental Immunology

Osteopontin-dependent regulation of Th1 and Th17 cytokine responses in Trypanosoma cruzi-infected C57BL/6 mice

(2012) Miguel H. Santamaría et al.   CYTOKINE

Thrombin-cleaved Fragments of Osteopontin Are Overexpressed in Malignant Glial Tumors and Provide a Molecular Niche with Survival Advantage

(2012) Yasuto Yamaguchi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Thrombin and Cancer: From Molecular Basis to Therapeutic Implications

(2012) Massimo Franchini et al.   SEMINARS IN THROMBOSIS AND HEMOSTASIS

Fibrinogen-induced perivascular microglial clustering is required for the development of axonal damage in neuroinflammation

(2012) Dimitrios Davalos et al.   Nature Communications

Osteopontin: A key link between immunity, inflammation and the central nervous system

(2012) Amanda Brown   Translational Neuroscience

Deletion of the thrombin cleavage domain of osteopontin mediates breast cancer cell adhesion, proteolytic activity, tumorgenicity, and metastasis

(2011) Michel S Beausoleil et al.   BMC CANCER

Simple scale-up of recombinant antibody production using an UCOE containing vector

(2011) Sabrina Boscolo et al.   New Biotechnology

Role of osteopontin in synovial Th17 differentiation in rheumatoid arthritis

(2010) Guangjie Chen et al.   ARTHRITIS AND RHEUMATISM

Blockade of osteopontin reduces alloreactive CD8+ T cell-mediated graft-versus-host disease

(2010) F. Zhao et al.   BLOOD

Osteopontin; as a Target Molecule for the Treatment of Inflammatory Diseases

(2010) Junko Morimoto et al.   CURRENT DRUG TARGETS

Role of tissue inhibitor of metalloproteinases-1 in the development of autoimmune lymphoproliferation

(2010) E. Boggio et al.   HAEMATOLOGICA

Thrombin-cleaved Osteopontin Levels in Synovial Fluid Correlate with Disease Severity of Knee Osteoarthritis

(2010) M. HASEGAWA et al.   JOURNAL OF RHEUMATOLOGY

Spinal Microglial Expression and Mechanical Hypersensitivity in a Postoperative Pain Model: Comparison with a Neuropathic Pain Model

(2009) Naomi Ito et al.   ANESTHESIOLOGY

Thrombin-cleaved osteopontin regulates hemopoietic stem and progenitor cell functions through interactions with  9 1 and  4 1 integrins

(2009) J. Grassinger et al.   BLOOD

Osteopontin: A multifunctional protein at the crossroads of inflammation, atherosclerosis, and vascular calcification

(2009) Hyun-Ju Cho et al.   Current Atherosclerosis Reports

Osteopontin induces angiogenesis through activation of PI3K/AKT and ERK1/2 in endothelial cells

(2009) J Dai et al.   ONCOGENE

Serum levels of osteopontin are increased in SIRS and sepsis

(2008) Rosanna Vaschetto et al.   INTENSIVE CARE MEDICINE

Proteomic analysis of active multiple sclerosis lesions reveals therapeutic targets

(2008) May H. Han et al.   NATURE