Article
Medicine, General & Internal
Cornelis F. Vos, Sophie E. ter Hark, Arnt F. A. Schellekens, Jan Spijker, Annemarie van der Meij, Anne J. Grotenhuis, Raluca Mihaescu, Wietske Kievit, Rogier Donders, Rob E. Aarnoutse, Marieke J. H. Coenen, Joost G. E. Janzing
Summary: This randomized clinical trial found that pharmacogenetics-informed treatment with tricyclic antidepressants (TCAs) resulted in faster attainment of therapeutic drug concentrations and potentially fewer adverse effects in patients with unipolar major depressive disorder. However, the evidence for the clinical benefit of pharmacogenetics-informed treatment with TCAs is still limited.
Article
Computer Science, Information Systems
Qiang Lin, Min Men, Liran Yang, Ping Zhong
Summary: This paper presents a novel supervised multi-view feature selection method based on locally sparse regularization and block computing. By dividing the multi-view dataset into sub-blocks and utilizing ADMM, a sharing sub-model is proposed for feature selection on each class. The proposed method outperforms several state-of-the-art feature selection methods in terms of classification accuracy and training speed.
INFORMATION SCIENCES
(2022)
Article
Materials Science, Multidisciplinary
Shengtao Jiang, Steven R. White, A. L. Chernyshev
Summary: This study investigates the phase diagram of the quantum S = 1/2 J(1)-J(3) ferro-antiferromagnetic model on the honeycomb lattice and finds that it differs significantly from the classical phase diagram. The introduction of double-zigzag and Ising-z phases as intermediaries between ferromagnetic and zigzag states is observed, extending beyond their classical regions of stability.
Article
Engineering, Multidisciplinary
Yan Qin, Renke Kang, Yidan Wang, Jiansong Sun, Zhigang Dong
Summary: This paper proposes a method combining dimensionality reduction with random sample consensus or regression analysis to distinguish noise from measurement data, and a directional extraction method for honeycomb core surface shape based on locally weighted regression. By establishing a highly realistic simulation method for honeycomb surfaces, the lack of honeycomb benchmarks is addressed.
Article
Mathematics, Applied
Cun-Qiang Miao, Wen-Ting Wu
Summary: Inspired by the greedy randomized Kaczmarz method, the study proposes a probability criterion for selecting submatrices and constructs the greedy randomized average block Kaczmarz method. Experimental results demonstrate the method's advantage over other methods.
JOURNAL OF COMPUTATIONAL AND APPLIED MATHEMATICS
(2022)
Article
Agronomy
Anastasios Katsileros, Nikolaos Antonetsis, Maria-Georgia Gkika, Eleni Tani, Penelope J. Bebeli, Ioannis Tokatlidis
Summary: Honeycomb Selection Design (HSD) is an innovative experimental method with a systematic and even entry arrangement, allowing for early single-plant selection and identification of superior genotypes. The 'rhoneycomb' is a free and open-source R package that provides construction, visualization, and analysis of HSDs.
Article
Automation & Control Systems
Miao Yu, Federico Bianchi, Luigi Piroddi
Summary: This study extends a randomized approach for identifying switched systems to estimate switching locations. The method extracts samples from a probability distribution of switched models and updates the distribution based on the associated model performances until convergence. The algorithm has been compared to existing methods and tested on benchmark examples to demonstrate its effectiveness.
NONLINEAR ANALYSIS-HYBRID SYSTEMS
(2023)
Article
Computer Science, Artificial Intelligence
Xingrun Wang, Xiaochen Yuan, Mianjie Li, Ying Sun, Jinyu Tian, Hongfei Guo, Jianqing Li
Summary: This paper proposes a parallel multiple watermarking method using adaptive inter-block correlation. By considering the image texture characteristics and using a texture complexity method, suitable adjacent blocks are selected for watermark embedding, ensuring good imperceptibility and robustness. The proposed scheme optimizes the watermark embedding algorithm to achieve parallel embedding of multiple watermarks, reducing time cost.
EXPERT SYSTEMS WITH APPLICATIONS
(2023)
Article
Mathematics, Applied
Yanjun Zhang, Hanyu Li
Summary: This paper proposes a randomized block Kaczmarz-Motzkin method for solving linear systems by introducing a subsampling strategy. This method allows one to determine the block size in advance and combines and extends the advantages of randomness and greed. Theoretical analysis shows that the proposed method converges linearly in expectation to the least-Euclidean-norm solution. Several numerical examples are reported to verify the efficiency and feasibility of the new method.
LINEAR ALGEBRA AND ITS APPLICATIONS
(2023)
Article
Chemistry, Physical
Lexin Ding, Stefan Knecht, Christian Schilling
Summary: The study proposes an effective optimization scheme for complete active space using quantum information (QICAS). It is shown that the energetically optimal nonactive spaces are predominantly those that contain the least entanglement.
JOURNAL OF PHYSICAL CHEMISTRY LETTERS
(2023)
Article
Mathematics, Applied
Feng Yin, Bu-Yue Zhang, Guang-Xin Huang
Summary: This paper presents a partial block randomized extended Kaczmarz (PBREK) method for solving large overdetermined inconsistent linear system of equations Ax = b. The convergence theorem of the PBREK method is derived. Several examples are given to illustrate the effectiveness of the proposed PBREK method compared with the prevuious PREK method and the randomized extended Kaczmarz (REK) method.
Article
Polymer Science
Nico Alleva, Katharina Eigen, David Y. W. Ng, Tanja Weil
Summary: We propose a simple and versatile method to purify and isolate DNA-polymer conjugates from various types of uncharged homo, random, or block copolymer families. Anion exchange chromatography is utilized for separation and recovery of excess unreacted polymer and oligonucleotide. With a high yield and efficient purification process, this method demonstrates its broad applicability for different polymer families and DNA block lengths.
Article
Cardiac & Cardiovascular Systems
Saranda Haxha, Andrim Halili, Morten Malmborg, Ulrik Pedersen-Bjergaard, Berit T. Philbert, Tommi B. Lindhardt, Soeren Hoejberg, Anne-Marie Schjerning, Martin H. Ruwald, Gunnar H. Gislason, Christian Torp-Pedersen, Casper N. Bang
Summary: The present study aimed to determine the association between Type 2 diabetes mellitus (T2DM) and third-degree (complete) atrioventricular block. The results showed that T2DM was significantly associated with third-degree atrioventricular block, and this association remained in subgroups with other comorbidities.
EUROPEAN HEART JOURNAL
(2023)
Article
Engineering, Mechanical
Ye Yuan, Bin Liu, Han Jia, Chi Zhang, Zhiguo Zhang, Suhao Wang, Yuzhen Yang, Xun Wang, Xiaobin Cheng, Zhaoli Yan, Jun Yang
Summary: This article introduces a nondestructive testing method based on honeycomb structure. By analyzing and experimental testing, it is found that there is a special wave propagation gap in the honeycomb structure, which can be used to detect debonding defects. This method detects and locates the debonding defects in the honeycomb structure with high sensitivity and efficiency, and it has great potential to be widely used in field tests.
MECHANICAL SYSTEMS AND SIGNAL PROCESSING
(2023)
Article
Engineering, Electrical & Electronic
Takayuki Nagata, Keigo Yamada, Kumi Nakai, Yuji Saito, Taku Nonomura
Summary: The randomized group-greedy (RGG) method and its customized method are proposed for large-scale sensor selection problems. The customized method involves selecting a portion of the compressed sensor candidates using a low-cost method to compensate for the deterioration in the solution. The proposed method provides better optimization results than the original method with a similar computational cost.
IEEE SENSORS JOURNAL
(2023)
Article
Agronomy
Ilias D. Avdikos, Rafail Tagiakas, Ioannis Mylonas, Ioannis N. Xynias, Athanasios G. Mavromatis
Summary: This study demonstrates the possibility of achieving inbred vigor in tomatoes equal to or greater than hybrid vigor when cultivated under organic low input conditions. By following the appropriate breeding process and selecting in early generations under low-input conditions, it is possible to produce recombinant lines with inbred vigor in yield potential and fruit quality. These genetic materials can potentially serve as new cultivars adaptable to different farming systems, including organic, low-input, or high-input conditions.
Article
Agronomy
Pavlina Smutna, Ioannis Mylonas, Ioannis S. Tokatlidis
Summary: The study evaluated 23 wheat genotypes using stability models, revealing diverse genotype classifications into two groups based on agronomic and static aspects of stability. The loamy field was more representative of overall genotype performance, with the GGE biplot serving as an effective tool for assessing wheat genotypes in terms of general and specific adaptation. It is suggested to prefer favorable experimental conditions and apply the GGE model to identify genotypes promising for stable performance across wide agroecosystems.
INTERNATIONAL JOURNAL OF PLANT PRODUCTION
(2021)
Article
Green & Sustainable Science & Technology
Panayiota Papastylianou, Dimitrios N. Vlachostergios, Christos Dordas, Evangelia Tigka, Paschalis Papakaloudis, Anastasia Kargiotidou, Emmanouil Pratsinakis, Avraam Koskosidis, Chrysanthi Pankou, Angeliki Kousta, Ioannis Mylonas, Eleni Tani, Eleni M. Abraham, Maria Karatassiou, Stavroula Kostoula
Summary: The development of high yielding and stable cultivars of legume crops in various environments is crucial for farmer adoption. This study evaluated faba bean genotypes across different locations in Greece over two growing seasons, with environmental factors playing a significant role in influencing characteristics. GGE-biplot analysis identified three genotypic types with specific adaptation capacities, highlighting the importance of screening genotypes under diverse environmental conditions.
Article
Agronomy
Ilias D. Avdikos, Rafail Tagiakas, Pavlos Tsouvaltzis, Ioannis Mylonas, Ioannis N. Xynias, Athanasios G. Mavromatis
Summary: Tomato is a highly consumed fruit vegetable globally, rich in minerals, fiber, carotenoids, and vitamin C. Recent emphasis has been on breeding new tomato cultivars with nutraceutical value to strengthen the human immune system and provide protection against diseases. Inbreeding can reach and even surpass hybrid vigor, leading to the development of recombinant lines with integrated quality characteristics that serve as alternatives to hybrid cultivars with high nutritional values.
Article
Agronomy
Ilias D. Avdikos, Georgia-Maria Nteve, Athanasia Apostolopoulou, Rafail Tagiakas, Ioannis Mylonas, Ioannis N. Xynias, Fokion Papathanasiou, Panagiotis Kalaitzis, Athanasios G. Mavromatis
Summary: The study found that elite recombinant inbred lines can lead to higher levels of re-heterosis, improving yield and fruit quality. This suggests that dominance is not the sole factor in explaining heterosis in tomato. Selecting the most suitable genotype for organic cultivation under low input conditions is crucial.
Article
Green & Sustainable Science & Technology
Dimitrios N. Vlachostergios, Christos Noulas, Anastasia Kargiotidou, Dimitrios Baxevanos, Evangelia Tigka, Chrysanthi Pankou, Stavroula Kostoula, Dimitrios Beslemes, Maria Irakli, Miltiadis Tziouvalekas, Anastasios Lithourgidis, Ioannis Tokatlidis, Christos Dordas, Athanasios Mavromatis
Summary: The study identified suitable locations for high-yield and high-quality lentil production or breeding, based on a multi-location network evaluation of different genotypes over two growing seasons. Different locations showed optimal values for seed yield, crude protein, and cooking time, with Orestiada in Thrace recognized as the optimal location for lentil breeding. High-producing and adaptable genotypes were identified for cultivation or breeding programs.
Article
Chemistry, Multidisciplinary
Anthoula Gleridou, Ioannis Tokatlidis, Alexios Polidoros
Summary: Genetic differentiation among 40 lentil genotypes was tested using molecular markers. Results showed low variation among consecutive generations produced via honeycomb breeding methodology. Molecular analysis revealed that the variation was higher within each generation's population than between them. Population structure analysis indicated that ongoing selection could effectively alter the allelic composition in each generation.
APPLIED SCIENCES-BASEL
(2022)
Article
Plant Sciences
Ioannis Zafeiriou, Alexios N. Polidoros, Eirini Baira, Konstantinos M. Kasiotis, Kyriaki Machera, Photini Mylona
Summary: White lupin is an important legume crop with high protein content, but its high seed-quinolizidine alkaloid (QA) content poses challenges for direct consumption. Genetic diversity in Greek white lupin landrace germplasm shows potential for developing new elite cultivars with desirable traits for sustainable agriculture. Promising alleles for traits such as vernalization unresponsiveness and anthracnose resistance have been identified in the landraces, highlighting their value for future breeding efforts.
Article
Chemistry, Multidisciplinary
Murad Awad, Georgios Giannopoulos, Photini V. Mylona, Alexios N. Polidoros
Summary: The relationships between epiphytic microbiomes of different Vitis vinifera cultivars in the same vineyard and terroir were investigated using metagenomic analysis. The results showed that grapevine genotype and phenological stage significantly influenced microbial diversity and structure. Microbiome analysis could be an important molecular fingerprint for cultivars and provide a management tool for traceability of wine and grape end products.
APPLIED SCIENCES-BASEL
(2023)
Article
Agronomy
Athanasios Mavromatis, Irini Nianiou-Obeidat, Alexios Polidoros, Zoi Parissi, Eleni Tani, Maria Irakli, Konstantinos A. Aliferis, Ioannis Zafeiriou, Photini V. Mylona, Efi Sarri, Evgenia-Anna Papadopoulou, Rafail Tagiakas, Leonidas Kougiteas, Stavroula Kostoula, Eleni M. Abraham
Summary: This research studied commercial cultivars and advanced breeding lines of Lupinus albus using phenotypical, molecular, and biochemical data for breeding projects. There are differences in yield and nutritional value between commercial cultivars and advanced breeding lines, which can be utilized in breeding programs.
Article
Plant Sciences
Miltiadis Tziouvalekas, Evangelia Tigka, Anastasia Kargiotidou, Dimitrios Beslemes, Maria Irakli, Chrysanthi Pankou, Parthena Arabatzi, Maria Aggelakoudi, Ioannis Tokatlidis, Athanasios Mavromatis, Ruijun Qin, Christos Noulas, Dimitrios N. Vlachostergios
Summary: This study investigated the effects of genotype and growing environment on seed yield, crude protein, and mineral nutrients of lentils. The results showed that the growing environment was the main source of variation for these parameters. Ideal environments were identified for different parameters, and promising genotypes were also identified.
Article
Plant Sciences
Paolo Annicchiarico, Abco J. J. de Buck, Dimitrios N. N. Vlachostergios, Dennis Heupink, Avraam Koskosidis, Nelson Nazzicari, Margherita Crosta
Summary: This study assessed the phenotypic variation, trait architecture, and predictive ability of genome-enabled models for white lupin grown in different soil environments. The study found large genotype x environment interaction and low genetic correlation for grain yield and other traits across locations. GWAS identified significant SNP markers for various traits but with inconsistent results across locations, indicating polygenic trait control. Genomic selection showed moderate predictive ability for yield and lime susceptibility, supporting breeding programs.
Article
Plant Sciences
Dimitrios Beslemes, Evangelia Tigka, Ioannis Roussis, Ioanna Kakabouki, Antonios Mavroeidis, Dimitrios Vlachostergios
Summary: This study investigated the contribution of AMF inoculation to the growth and productivity of barley crops in both conventional and organic cropping systems. The results showed that AMF+ plants exhibited higher plant height and leaf area index (LAI), leading to increased biomass and seed yield. The AMF inoculated plants also showed higher values in nitrogen and phosphorus uptake and utilization indices. However, the level of fertilization, particularly inorganic fertilization, had a negative impact on AMF root colonization. It was concluded that substituting inorganic inputs with organic inputs and reducing inputs, combined with AMF inoculation, can make barley crop cultivation sustainable in Mediterranean climates.
Article
Plant Sciences
Stella Pegiou, Panagiotis Raptis, Ioannis Zafeiriou, Alexios N. Polidoros, Photini V. Mylona
Summary: Capparis spinosa, a widely distributed orphan shrub in the Mediterranean basin and Asia, has medicinal and culinary value. Due to limited cultivation efforts, caper parts are mainly collected from wild germplasm, leading to bottleneck events. Genetic diversity assessment of the species is crucial for conservation schemes. The study used DNA barcoding and molecular characterization to assess the genetic diversity of 8 C. spinosa populations in Greece. The results highlight the need for comprehensive caper germplasm characterization and conservation strategies.
JOURNAL OF APPLIED RESEARCH ON MEDICINAL AND AROMATIC PLANTS
(2023)
Article
Chemistry, Multidisciplinary
Ekaterini Koura, Adamantia Pistikoudi, Margaritis Tsifintaris, George Tsiolas, Evangelia Mouchtaropoulou, Christos Noutsos, Triantafyllos Karantakis, Athanasios Kouras, Athanasios Karanikolas, Anagnostis Argiriou, Irini Nianiou-Obeidat, Photini V. Mylona, Alexios N. Polidoros
Summary: This study explored the impact of seed maturity stages and phosphorus fertilization levels on gene expression in lentils and found that the seed maturity stage significantly influenced phenylpropanoid genes, while phosphorus fertilizer had a targeted effect on specific genes and gene clusters. These findings provide valuable information for enhancing lentil product quality through breeding programs.
APPLIED SCIENCES-BASEL
(2023)