Identification of Long Non‐Coding RNAs Deregulated in Multiple Myeloma Cells Resistant to Proteasome Inhibitors

Distinct lncRNA transcriptional fingerprints characterize progressive stages of multiple myeloma

(2016) Domenica Ronchetti et al.   Oncotarget

Abstract 153: Long non-coding RNAs deregulated in Multiple Myeloma impact therapeutic response to proteasome inhibitors

(2015) Ehsan Malek et al.   CANCER RESEARCH

Identification and validation of potential prognostic lncRNA biomarkers for predicting survival in patients with multiple myeloma

(2015) Meng Zhou et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Epigenetic silencing of a long non-coding RNA KIAA0495 in multiple myeloma

(2015) Kwan Yeung Wong et al.   Molecular Cancer

miRNAs in multiple myeloma – a survival relevant complex regulator of gene expression

(2015) Anja Seckinger et al.   Oncotarget

MALAT1 long non-coding RNA is overexpressed in multiple myeloma and may serve as a marker to predict disease progression

(2014) Shih-Feng Cho et al.   BMC CANCER

MicroRNA and Multiple Myeloma: from Laboratory Findings to Translational Therapeutic Approaches

(2014) Marco Rossi et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Circulating miRNA markers show promise as new prognosticators for multiple myeloma

(2014) A Rocci et al.   LEUKEMIA

MiR-29b replacement inhibits proteasomes and disrupts aggresome+autophagosome formation to enhance the antimyeloma benefit of bortezomib

(2014) S Jagannathan et al.   LEUKEMIA

The role of epigenetics in the biology of multiple myeloma

(2014) K Dimopoulos et al.   Blood Cancer Journal

PANORAMA 2: panobinostat in combination with bortezomib and dexamethasone in patients with relapsed and bortezomib-refractory myeloma

(2013) P. G. Richardson et al.   BLOOD

Improved risk stratification in myeloma using a microRNA-based classifier

(2013) Ping Wu et al.   BRITISH JOURNAL OF HAEMATOLOGY

Why Proteasome Inhibitors Cannot ERADicate Multiple Myeloma

(2013) Robert Z. Orlowski   CANCER CELL

Xbp1s-Negative Tumor B Cells and Pre-Plasmablasts Mediate Therapeutic Proteasome Inhibitor Resistance in Multiple Myeloma

(2013) Chungyee Leung-Hagesteijn et al.   CANCER CELL

Biological and Clinical Relevance of miRNA Expression Signatures in Primary Plasma Cell Leukemia

(2013) M. Lionetti et al.   CLINICAL CANCER RESEARCH

Aberrant microRNA expression in multiple myeloma

(2013) Konstantinos Dimopoulos et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

Non-coding RNA: a novel opportunity for the personalized treatment of multiple myeloma

(2013) Nicola Amodio et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

MicroRNA theragnostics for the clinical management of multiple myeloma

(2013) N Ahmad et al.   LEUKEMIA

Multiple myeloma

(2013) D. Smith et al.   BMJ-British Medical Journal

Promises and Challenges of MicroRNA-based Treatment of Multiple Myeloma

(2012) P. Tagliaferri et al.   CURRENT CANCER DRUG TARGETS

Novel classes of non-coding RNAs and cancer

(2012) Jiri Sana et al.   Journal of Translational Medicine

Circulating microRNA expression is associated with genetic subtype and survival of multiple myeloma

(2012) Jing-jing Huang et al.   MEDICAL ONCOLOGY

Redefining myeloma

(2012) S. Vincent Rajkumar et al.   Nature Reviews Clinical Oncology

Targeting the Ubiquitin+Proteasome System in Solid Tumors

(2012) James J. Driscoll et al.   SEMINARS IN HEMATOLOGY

Downregulated plasma miR-92a levels have clinical impact on multiple myeloma and related disorders

(2012) S Yoshizawa et al.   Blood Cancer Journal

Perspectives of Long Non-Coding RNAs in Cancer Diagnostics

(2012) Eduardo M. Reis et al.   Frontiers in Genetics

miR-34 – a microRNA replacement therapy is headed to the clinic

(2012) Andreas G. Bader   Frontiers in Genetics

MicroRNA expression in multiple myeloma is associated with genetic subtype, isotype and survival

(2011) Jianxiang Chi et al.   Biology Direct

MicroRNA signatures characterize multiple myeloma patients

(2011) S L Corthals et al.   LEUKEMIA

Molecular Mechanisms of Long Noncoding RNAs

(2011) Kevin C. Wang et al.   MOLECULAR CELL

Extensive and coordinated transcription of noncoding RNAs within cell-cycle promoters

(2011) Tiffany Hung et al.   NATURE GENETICS

Multiple Myeloma

(2011) Antonio Palumbo et al.   NEW ENGLAND JOURNAL OF MEDICINE

Posttranscriptional Upregulation by MicroRNAs

(2011) Shobha Vasudevan   Wiley Interdisciplinary Reviews-RNA

The Promise of MicroRNA Replacement Therapy

(2010) A. G. Bader et al.   CANCER RESEARCH

Building on bortezomib: second-generation proteasome inhibitors as anti-cancer therapy

(2010) Lawrence R. Dick et al.   DRUG DISCOVERY TODAY

Deregulation of microRNA expression in the different genetic subtypes of multiple myeloma and correlation with gene expression profiling

(2010) N C Gutiérrez et al.   LEUKEMIA

High-risk myeloma is associated with global elevation of miRNAs and overexpression ofEIF2C2/AGO2

(2010) Yiming Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Long Noncoding RNA as Modular Scaffold of Histone Modification Complexes

(2010) M.-C. Tsai et al.   SCIENCE

Noncoding RNA Gas5 Is a Growth Arrest- and Starvation-Associated Repressor of the Glucocorticoid Receptor

(2010) T. Kino et al.   Science Signaling

The 26S proteasome: assembly and function of a destructive machine

(2010) Nerea Gallastegui et al.   TRENDS IN BIOCHEMICAL SCIENCES

RNA regulation of epigenetic processes

(2009) John S. Mattick et al.   BIOESSAYS

Induction of angiogenesis by normal and malignant plasma cells

(2009) D. Hose et al.   BLOOD

Identification of microRNA expression patterns and definition of a microRNA/mRNA regulatory network in distinct molecular groups of multiple myeloma

(2009) M. Lionetti et al.   BLOOD

MicroRNAs 15a and 16 regulate tumor proliferation in multiple myeloma

(2009) A. M. Roccaro et al.   BLOOD

Evolution and Functions of Long Noncoding RNAs

(2009) Chris P. Ponting et al.   CELL

Many facets of bortezomib resistance/susceptibility

(2008) S. Kumar et al.   BLOOD

MicroRNAs regulate critical genes associated with multiple myeloma pathogenesis

(2008) F. Pichiorri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA