Huperzine A Provides Robust and Sustained Protection against Induced Seizures in Scn1a Mutant Mice

Decreased Accumulation of Subcellular Amyloid-β with Improved Mitochondrial Function Mediates the Neuroprotective Effect of Huperzine A

(2018) Ling Yang et al.   JOURNAL OF ALZHEIMERS DISEASE

Efficacy of antiepileptic drugs for the treatment of Dravet syndrome with different genotypes

(2016) Xiu-Yu Shi et al.   BRAIN & DEVELOPMENT

Huperzine A prophylaxis against pentylenetetrazole-induced seizures in rats is associated with increased cortical inhibition

(2015) R. Gersner et al.   EPILEPSY RESEARCH

Progress report on new antiepileptic drugs: A summary of the Twelfth Eilat Conference (EILAT XII)

(2015) Meir Bialer et al.   EPILEPSY RESEARCH

Decreased Subcortical Cholinergic Arousal in Focal Seizures

(2015) Joshua E. Motelow et al.   NEURON

Nav1.1 Modulation by a Novel Triazole Compound Attenuates Epileptic Seizures in Rodents

(2014) John Gilchrist et al.   ACS Chemical Biology

Impaired excitability of somatostatin- and parvalbumin-expressing cortical interneurons in a mouse model of Dravet syndrome

(2014) C. Tai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hippocampal hyperexcitability and specific epileptiform activity in a mouse model of Dravet syndrome

(2013) Camille Liautard et al.   EPILEPSIA

Altered sleep regulation in a mouse model ofSCN1A-derived genetic epilepsy with febrile seizures plus (GEFS+)

(2013) Ligia A. Papale et al.   EPILEPSIA

Huperzine A for Alzheimer’s Disease: A Systematic Review and Meta-Analysis of Randomized Clinical Trials

(2013) Guoyan Yang et al.   PLoS One

Effects of an epilepsy-causing mutation in the SCN1A sodium channel gene on cocaine-induced seizure susceptibility in mice

(2013) Ryan H. Purcell et al.   PSYCHOPHARMACOLOGY

Sodium channel SCN8A (Nav1.6): properties and de novo mutations in epileptic encephalopathy and intellectual disability

(2013) Janelle E. O'Brien et al.   Frontiers in Genetics

A combination of [+] and [−]-Huperzine A improves protection against soman toxicity compared to [+]-Huperzine A in guinea pigs

(2012) Ying Wang et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Efficacy of stiripentol in hyperthermia-induced seizures in a mouse model of Dravet syndrome

(2012) Dezhi Cao et al.   EPILEPSIA

Huperzine A ameliorates experimental autoimmune encephalomyelitis via the suppression of T cell-mediated neuronal inflammation in mice

(2012) Jun Wang et al.   EXPERIMENTAL NEUROLOGY

Preferential inactivation of Scn1a in parvalbumin interneurons increases seizure susceptibility

(2012) Stacey B. Dutton et al.   NEUROBIOLOGY OF DISEASE

Treatment with Huperzine A Improves Cognition in Vascular Dementia Patients

(2011) Zhi-Qiang Xu et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Protective effect of the ketogenic diet in Scn1a mutant mice

(2011) Stacey B. B. Dutton et al.   EPILEPSIA

The pharmacologic treatment of Dravet syndrome

(2011) Catherine Chiron et al.   EPILEPSIA

Therapy for hyperthermia-induced seizures in Scn1a mutant rats

(2011) Keiichiro Hayashi et al.   EPILEPSIA

AChE deficiency or inhibition decreases apoptosis and p53 expression and protects renal function after ischemia/reperfusion

(2010) Weiyuan Ye et al.   APOPTOSIS

Sodium channel SCN1A and epilepsy: Mutations and mechanisms

(2010) Andrew Escayg et al.   EPILEPSIA

Presynaptic muscarinic receptor subtypes involved in the enhancement of spontaneous GABAergic postsynaptic currents in hippocampal neurons

(2010) J. C. González et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Altered Function of theSCN1AVoltage-gated Sodium Channel Leads to γ-Aminobutyric Acid-ergic (GABAergic) Interneuron Abnormalities

(2010) Melinda S. Martin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NaV1.1 channels and epilepsy

(2010) William A. Catterall et al.   JOURNAL OF PHYSIOLOGY-LONDON

A long-term follow-up study of Dravet syndrome up to adulthood

(2009) Mari Akiyama et al.   EPILEPSIA

Clinical use of an herbal-derived compound (Huperzine A) to treat putative complex partial seizures in a dog

(2009) Barbara M. Schneider et al.   EPILEPSY & BEHAVIOR

TheSCN1Avariant database: a novel research and diagnostic tool

(2009) Lieve RF Claes et al.   HUMAN MUTATION

Efficacy and safety of natural acetylcholinesterase inhibitor huperzine A in the treatment of Alzheimer’s disease: an updated meta-analysis

(2009) Bai-song Wang et al.   JOURNAL OF NEURAL TRANSMISSION

Huperzine a provides neuroprotection against several cell death inducers usingin vitro model systems of motor neuron cell death

(2009) Richelle A. Hemendinger et al.   NEUROTOXICITY RESEARCH

Systemic administration of the potential countermeasure huperzine reversibly inhibits central and peripheral acetylcholinesterase activity without adverse cognitive–behavioral effects

(2009) Todd M. Myers et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Temperature- and age-dependent seizures in a mouse model of severe myoclonic epilepsy in infancy

(2009) J. C. Oakley et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A catalog of SCN1A variants

(2008) Christoph Lossin   BRAIN & DEVELOPMENT

[+]-Huperzine A treatment protects against N-methyl-d-aspartate-induced seizure/status epilepticus in rats

(2008) Brian R. Coleman et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Huperzine A exhibits anti-inflammatory and neuroprotective effects in a rat model of transient focal cerebral ischemia

(2008) Zhi-Fei Wang et al.   JOURNAL OF NEUROCHEMISTRY