Fluoxetine Prevents Aβ1-42-Induced Toxicity via a Paracrine Signaling Mediated by Transforming-Growth-Factor-β1

A Link Between Nerve Growth Factor Metabolic Deregulation and Amyloid-β-Driven Inflammation in Down Syndrome

(2016) Maria Florencia Iulita et al.   CNS & Neurological Disorders-Drug Targets

The amyloid hypothesis of Alzheimer's disease at 25 years

(2016) Dennis J Selkoe et al.   EMBO Molecular Medicine

Long-term Ameliorative Effects of the Antidepressant Fluoxetine Exposure on Cognitive Deficits in 3 × TgAD Mice

(2016) Li Jin et al.   MOLECULAR NEUROBIOLOGY

Neuroprotective effects of the monoamine oxidase inhibitor tranylcypromine and its amide derivatives against Aβ(1–42)-induced toxicity

(2015) Filippo Caraci et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Three dimensions of the amyloid hypothesis: time, space and 'wingmen'

(2015) Erik S Musiek et al.   NATURE NEUROSCIENCE

Duality of Antidepressants and Neuroprotectants

(2015) Yousef Tizabi   NEUROTOXICITY RESEARCH

A key role for TGF-β1 in hippocampal synaptic plasticity and memory

(2015) Filippo Caraci et al.   Scientific Reports

Modulatory Activity of Soluble Beta Amyloid on HPA Axis Function in Rats

(2015) Maria Morgese et al.   CURRENT PHARMACEUTICAL DESIGN

Searching for Disease-Modifying Drugs in AD: Can We Combine Neuropsychological Tools with Biological Markers?

(2014) Filippo Caraci et al.   CNS & Neurological Disorders-Drug Targets

Fluoxetine Improves Behavioral Performance by Suppressing the Production of Soluble β-Amyloid in APP/PS1 Mice

(2014) Junhui Wang et al.   Current Alzheimer Research

Memantine prevents memory consolidation failure induced by soluble beta amyloid in rats

(2014) Paolo Tucci et al.   Frontiers in Behavioral Neuroscience

Prenatal pharmacotherapy rescues brain development in a Down’s syndrome mouse model

(2013) Sandra Guidi et al.   BRAIN

Glia: An Important Target for Anti-Inflammatory and Antidepressant Activity

(2013) Sadayuki Hashioka et al.   CURRENT DRUG TARGETS

N-acetyl-cysteine prevents toxic oxidative effects induced by IFN-α in human neurons

(2013) Silvia Alboni et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Alzheimer disease therapy—moving from amyloid-β to tau

(2013) Ezio Giacobini et al.   Nature Reviews Neurology

Fluoxetine inhibits transient global ischemia-induced hippocampal neuronal death and memory impairment by preventing blood–brain barrier disruption

(2013) Jee Y. Lee et al.   NEUROPHARMACOLOGY

Role of nonsynaptic GluN2B-containing NMDA receptors in excitotoxicity: Evidence that fluoxetine selectively inhibits these receptors and may have neuroprotective effects

(2012) E.S. Vizi et al.   BRAIN RESEARCH BULLETIN

Optimal Dosages of Fluoxetine in the Treatment of Hypoxic Brain Injury Induced by 3-Nitropropionic Acid: Implications for the Adjunctive Treatment of Patients after Acute Ischemic Stroke

(2012) Bing-Gen Zhu et al.   CNS Neuroscience & Therapeutics

Depression and the risk for dementia

(2012) Lars Vedel Kessing   CURRENT OPINION IN PSYCHIATRY

Central effects of a local inflammation in three commonly used mouse strains with a different anxious phenotype

(2011) Cristina Benatti et al.   BEHAVIOURAL BRAIN RESEARCH

Regulation of matrix metalloproteinase 2 by oligomeric amyloid β protein

(2011) Wenjun Li et al.   BRAIN RESEARCH

The CC genotype of transforming growth factor-β1 increases the risk of late-onset Alzheimer's disease and is associated with AD-related depression

(2011) Filippo Caraci et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Fluoxetine protects neurons against microglial activation-mediated neurotoxicity

(2011) Feng Zhang et al.   PARKINSONISM & RELATED DISORDERS

Serotonin signaling is associated with lower amyloid-  levels and plaques in transgenic mice and humans

(2011) J. R. Cirrito et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fluoxetine regulates the expression of neurotrophic/growth factors and glucose metabolism in astrocytes

(2011) Igor Allaman et al.   PSYCHOPHARMACOLOGY

Soluble βamyloid1-42: a critical player in producing behavioural and biochemical changes evoking depressive-related state?

(2010) M Colaianna et al.   BRITISH JOURNAL OF PHARMACOLOGY

Targeting Group II Metabotropic Glutamate (mGlu) Receptors for the Treatment of Psychosis Associated with Alzheimer's Disease: Selective Activation of mGlu2 Receptors Amplifies  -Amyloid Toxicity in Cultured Neurons, Whereas Dual Activation of mGlu2 and mGlu3 Receptors Is Neuroprotective

(2010) F. Caraci et al.   MOLECULAR PHARMACOLOGY

TGF-β1 Pathway as a New Target for Neuroprotection in Alzheimer's Disease

(2009) Filippo Caraci et al.   CNS Neuroscience & Therapeutics

Management of agitation and aggression associated with Alzheimerʼs disease: controversies and possible solutions

(2009) Clive Ballard et al.   CURRENT OPINION IN PSYCHIATRY

Depression and Alzheimer's disease: Neurobiological links and common pharmacological targets

(2009) Filippo Caraci et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Efficacy of SSRIs on cognition of Alzheimer's disease patients treated with cholinesterase inhibitors

(2009) Luca Rozzini et al.   INTERNATIONAL PSYCHOGERIATRICS

Antidepressants and dementia

(2009) Lars Vedel Kessing et al.   JOURNAL OF AFFECTIVE DISORDERS

 -Amyloid Monomers Are Neuroprotective

(2009) M. L. Giuffrida et al.   JOURNAL OF NEUROSCIENCE

Neuronal plasticity: A link between stress and mood disorders

(2009) Francesca Calabrese et al.   PSYCHONEUROENDOCRINOLOGY

The role of proteases in transforming growth factor-β activation

(2008) G JENKINS   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Fluoxetine affords robust neuroprotection in the postischemic brain via its anti-inflammatory effect

(2008) Chae-Moon Lim et al.   JOURNAL OF NEUROSCIENCE RESEARCH

TGF-β1 protects against Aβ-neurotoxicity via the phosphatidylinositol-3-kinase pathway

(2008) Filippo Caraci et al.   NEUROBIOLOGY OF DISEASE

Antidepressant treatments regulate matrix metalloproteinases-2 and -9 (MMP-2/MMP-9) and tissue inhibitors of the metalloproteinases (TIMPS 1-4) in the adult rat hippocampus

(2008) Madhurima Benekareddy et al.   SYNAPSE