Neuromuscular Junction Impairment in Amyotrophic Lateral Sclerosis: Reassessing the Role of Acetylcholinesterase

Loss of C9ORF72 impairs autophagy and synergizes with polyQ Ataxin‐2 to induce motor neuron dysfunction and cell death

(2016) Chantal Sellier et al.   EMBO JOURNAL

Neuromuscular junction immaturity and muscle atrophy are hallmarks of the ColQ-deficient mouse, a model of congenital myasthenic syndrome with acetylcholinesterase deficiency

(2016) Séverine M. Sigoillot et al.   FASEB JOURNAL

Axonal degeneration, distal collateral branching and neuromuscular junction architecture alterations occur prior to symptom onset in the SOD1G93A mouse model of amyotrophic lateral sclerosis

(2016) Jayden A. Clark et al.   JOURNAL OF CHEMICAL NEUROANATOMY

ALS-associated mutant FUS induces selective motor neuron degeneration through toxic gain of function

(2016) Aarti Sharma et al.   Nature Communications

C9orf72 BAC Transgenic Mice Display Typical Pathologic Features of ALS/FTD

(2015) Jacqueline G. O’Rourke et al.   NEURON

Defining the genetic connection linking amyotrophic lateral sclerosis (ALS) with frontotemporal dementia (FTD)

(2015) Serena Lattante et al.   TRENDS IN GENETICS

A delicate balance: role of MMP-9 in brain development and pathophysiology of neurodevelopmental disorders

(2015) Sarah M. Reinhard et al.   Frontiers in Cellular Neuroscience

Schwann Cells Sense and Control Acetylcholine Spillover at the Neuromuscular Junction by  7 Nicotinic Receptors and Butyrylcholinesterase

(2014) K. A. Petrov et al.   JOURNAL OF NEUROSCIENCE

Motor neurons and the generation of spinal motor neuron diversity

(2014) Nicolas Stifani   Frontiers in Cellular Neuroscience

Loss of function of C9orf72 causes motor deficits in a zebrafish model of Amyotrophic Lateral Sclerosis

(2013) Sorana Ciura et al.   ANNALS OF NEUROLOGY

Abnormal mitochondrial transport and morphology are common pathological denominators in SOD1 and TDP43 ALS mouse models

(2013) Jordi Magrané et al.   HUMAN MOLECULAR GENETICS

TARDBPandFUSMutations Associated with Amyotrophic Lateral Sclerosis: Summary and Update

(2013) Serena Lattante et al.   HUMAN MUTATION

Early presymptomatic cholinergic dysfunction in a murine model of amyotrophic lateral sclerosis

(2013) Caty Casas et al.   Brain and Behavior

Specific binding of collagen Q to the neuromuscular junction is exploited to cure congenital myasthenia and to explore bases of myasthenia gravis

(2012) Kinji Ohno et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Readthrough Acetylcholinesterase Is Increased in Human Liver Cirrhosis

(2012) María-Salud García-Ayllón et al.   PLoS One

Amyotrophic lateral sclerosis

(2011) Matthew C Kiernan et al.   LANCET

To build a synapse: signaling pathways in neuromuscular junction assembly

(2010) H. Wu et al.   DEVELOPMENT

Expression of cholinesterases in human kidney and its variation in renal cell carcinoma types

(2010) Encarnación Muñoz-Delgado et al.   FEBS Journal

Nuclear factor TDP-43 can affect selected microRNA levels

(2010) Emanuele Buratti et al.   FEBS Journal

TDP-43 and FUS/TLS: emerging roles in RNA processing and neurodegeneration

(2010) C. Lagier-Tourenne et al.   HUMAN MOLECULAR GENETICS

The “Dying-Back” Phenomenon of Motor Neurons in ALS

(2010) Michal Dadon-Nachum et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

ColQ Controls Postsynaptic Differentiation at the Neuromuscular Junction

(2010) S. M. Sigoillot et al.   JOURNAL OF NEUROSCIENCE

Altered Levels of Acetylcholinesterase in Alzheimer Plasma

(2010) María-Salud García-Ayllón et al.   PLoS One

Deficits in axonal transport precede ALS symptoms in vivo

(2010) L. G. Bilsland et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neuromuscular junction destruction during amyotrophic lateral sclerosis: insights from transgenic models

(2009) Luc Dupuis et al.   CURRENT OPINION IN PHARMACOLOGY

Cholinesterases and the basal lamina at vertebrate neuromuscular junctions

(2009) Jean Massoulié et al.   CURRENT OPINION IN PHARMACOLOGY

Rapsyn interacts with the muscle acetylcholine receptor via α-helical domains in the α, β, and ε subunit intracellular loops

(2009) Y. Lee et al.   NEUROSCIENCE

Neuromuscular dysfunction in the mutant superoxide dismutase mouse model of amyotrophic lateral sclerosis

(2008) Wade S. Parkhouse et al.   Amyotrophic Lateral Sclerosis

Skeletal Muscle Is a Primary Target of SOD1G93A-Mediated Toxicity

(2008) Gabriella Dobrowolny et al.   Cell Metabolism

Demenz mit Lewy-Körperchen und verminderter Dopamin-Transporter-Bindung verweist auf Acetylcholin-Mangel

(2008) H Förstl et al.   DEUTSCHE MEDIZINISCHE WOCHENSCHRIFT

Biology and pathology of nonmyelinating Schwann cells

(2008) John W. Griffin et al.   GLIA

Transgenics, toxicity and therapeutics in rodent models of mutant SOD1-mediated familial ALS

(2008) B TURNER et al.   PROGRESS IN NEUROBIOLOGY