Distinct and Cooperative Functions for the Protocadherin-α, -β and -γ Clusters in Neuronal Survival and Axon Targeting

Establishment of high reciprocal connectivity between clonal cortical neurons is regulated by the Dnmt3b DNA methyltransferase and clustered protocadherins

(2016) Etsuko Tarusawa et al.   BMC BIOLOGY

Structural Basis of Diverse Homophilic Recognition by Clustered α- and β-Protocadherins

(2016) Kerry Marie Goodman et al.   NEURON

Molecular Logic of Neuronal Self-Recognition through Protocadherin Domain Interactions

(2015) Rotem Rubinstein et al.   CELL

Impaired clustered protocadherin-α leads to aggregated retinogeniculate terminals and impaired visual acuity in mice

(2015) Reiko Meguro et al.   JOURNAL OF NEUROCHEMISTRY

Structure and Sequence Analyses of Clustered Protocadherins Reveal Antiparallel Interactions that Mediate Homophilic Specificity

(2015) John M. Nicoludis et al.   STRUCTURE

Single-Cell Identity Generated by Combinatorial Homophilic Interactions between α, β, and γ Protocadherins

(2014) Chan Aye Thu et al.   CELL

Genetic Basis of Neuronal Individuality in the Mammalian Brain

(2013) Takeshi Yagi   JOURNAL OF NEUROGENETICS

Maturation of postnatally generated olfactory bulb granule cells depends on functional γ-protocadherin expression

(2013) Julia Ledderose et al.   Scientific Reports

Visual Map Shifts based on Whisker-Guided Cues in the Young Mouse Visual Cortex

(2013) Kohei Yoshitake et al.   Cell Reports

Protocadherins, not prototypical: a complex tale of their interactions, expression, and functions

(2013) Joshua A. Weiner et al.   Frontiers in Molecular Neuroscience

Cellular Mechanisms Underlying Spatiotemporal Features of Cholinergic Retinal Waves

(2012) K. J. Ford et al.   JOURNAL OF NEUROSCIENCE

Guidance-Cue Control of Horizontal Cell Morphology, Lamination, and Synapse Formation in the Mammalian Outer Retina

(2012) R. L. Matsuoka et al.   JOURNAL OF NEUROSCIENCE

The General Transcription Factor TAF7 Is Essential for Embryonic Development but Not Essential for the Survival or Differentiation of Mature T Cells

(2012) A. Gegonne et al.   MOLECULAR AND CELLULAR BIOLOGY

Protocadherins mediate dendritic self-avoidance in the mammalian nervous system

(2012) Julie L. Lefebvre et al.   NATURE

γ-Protocadherins Control Cortical Dendrite Arborization by Regulating the Activity of a FAK/PKC/MARCKS Signaling Pathway

(2012) Andrew M. Garrett et al.   NEURON

Functional Significance of Isoform Diversification in the Protocadherin Gamma Gene Cluster

(2012) Weisheng V. Chen et al.   NEURON

Restoration of Contralateral Representation in the Mouse Somatosensory Cortex after Crossing Nerve Transfer

(2012) Haruyoshi Yamashita et al.   PLoS One

Protocadherin clusters and cell adhesion kinase regulate dendrite complexity through Rho GTPase

(2012) Lun Suo et al.   Journal of Molecular Cell Biology

Molecular codes for neuronal individuality and cell assembly in the brain

(2012) Takeshi Yagi   Frontiers in Molecular Neuroscience

Constitutively expressed Protocadherin-α regulates the coalescence and elimination of homotypic olfactory axons through its cytoplasmic region

(2012) Sonoko Hasegawa et al.   Frontiers in Molecular Neuroscience

Single-neuron diversity generated by Protocadherin-β cluster in mouse central and peripheral nervous systems

(2012) Keizo Hirano et al.   Frontiers in Molecular Neuroscience

Identification of the Cluster Control Region for the Protocadherin-β Genes Located beyond the Protocadherin-γ Cluster

(2011) Shinnichi Yokota et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Locomotor-related activity of GABAergic interneurons localized in the ventrolateral region in the isolated spinal cord of neonatal mice

(2011) Hiroshi Nishimaru et al.   JOURNAL OF NEUROPHYSIOLOGY

The physiological roles of vesicular GABA transporter during embryonic development: a study using knockout mice

(2011) Kenzi Saito et al.   Molecular Brain

Direct and Indirect Regulation of Spinal Cord Ia Afferent Terminal Formation by the γ-Protocadherins

(2011) Tuhina Prasad et al.   Frontiers in Molecular Neuroscience

Chemoaffinity Revisited: Dscams, Protocadherins, and Neural Circuit Assembly

(2010) S. Lawrence Zipursky et al.   CELL

Combinatorial homophilic interaction between  -protocadherin multimers greatly expands the molecular diversity of cell adhesion

(2010) D. Schreiner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Total Expression and Dual Gene-regulatory Mechanisms Maintained in Deletions and Duplications of thePcdhaCluster

(2009) Yukiko Noguchi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Protocadherin-  Family Is Required for Serotonergic Projections to Appropriately Innervate Target Brain Areas

(2009) S. Katori et al.   JOURNAL OF NEUROSCIENCE

Cone Contacts, Mosaics, and Territories of Bipolar Cells in the Mouse Retina

(2009) H. Wassle et al.   JOURNAL OF NEUROSCIENCE

Proteomics Analysis Reveals Overlapping Functions of Clustered Protocadherins

(2009) Meng-Hsuan Han et al.   MOLECULAR & CELLULAR PROTEOMICS

A differential developmental pattern of spinal interneuron apoptosis during synaptogenesis: insights from genetic analyses of the protocadherin-  gene cluster

(2008) T. Prasad et al.   DEVELOPMENT

 -Protocadherins regulate neuronal survival but are dispensable for circuit formation in retina

(2008) J. L. Lefebvre et al.   DEVELOPMENT

Inhibition of protocadherin-α function results in neuronal death in the developing zebrafish

(2008) Michelle R. Emond et al.   DEVELOPMENTAL BIOLOGY

Down-regulation of protocadherin-α A isoforms in mice changes contextual fear conditioning and spatial working memory

(2008) Emi Fukuda et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

α- and γ-Protocadherins Negatively Regulate PYK2

(2008) Jian Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The protocadherin-α family is involved in axonal coalescence of olfactory sensory neurons into glomeruli of the olfactory bulb in mouse

(2008) Sonoko Hasegawa et al.   MOLECULAR AND CELLULAR NEUROSCIENCE