Article
Cell Biology
Johannes M. Wagner, Annalena Wille, Maria Fueth, Sarah Weske, Sebastian Lotzien, Felix Reinkemeier, Christoph Wallner, Alexander Sogorski, Stephanie Dittfeld, Mustafa Becerikli, Thomas A. Schildhauer, Marcus Lehnhardt, Bodo Levkau, Bjorn Behr
Summary: This study found that inhibition of S1P lyase can increase S1P levels and enhance osteogenesis and angiogenesis in a model of posttraumatic osteomyelitis, promoting bone regeneration, which may be a potential therapeutic target for treating posttraumatic osteomyelitis.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
(2023)
Article
Cell & Tissue Engineering
J. Shen, D. Sun, S. Yu, J. Fu, X. Wang, S. Wang, Z. Xie
Summary: Treatment of chronic osteomyelitis in young patients is challenging. This study aimed to compare the clinical effectiveness of BMCA and BMAA in children with long bone COM, finding that BMCA led to significantly shorter healing time.
BONE & JOINT RESEARCH
(2021)
Article
Agricultural Engineering
Jialing Ni, Jiayuan Ji, Kengo Kubota, Yu-You Li
Summary: This study investigated the concentration-dependent effects of sodium hypochlorite on biodegradation performance and microbial activity. The results showed that methane production and microbial community were almost unaffected within a certain concentration range. At high concentrations, microbial products could protect or recover the activity of anaerobic microorganisms.
BIORESOURCE TECHNOLOGY
(2022)
Article
Chemistry, Multidisciplinary
Ni Su, Cassandra Villicana, Danial Barati, Peyton Freeman, Ying Luo, Fan Yang
Summary: A new method for treating critical size cranial bone defects by using mesenchymal stem cell membrane (MSCM)-coated microribbon (mu RB) scaffolds via targeting immunomodulation is reported. The study shows that MSCM coating promotes macrophage polarization, induces CD8+ T cell apoptosis, and enhances regulatory T cell differentiation. These results establish cell membrane-coated microribbon scaffolds as a promising strategy for treating critical size bone defects via immunomodulation.
ADVANCED MATERIALS
(2023)
Review
Cell & Tissue Engineering
J. Shen, Z. Wei, S. Wang, X. Wang, W. Lin, L. Liu, G. Wang
Summary: This study evaluated the effectiveness of the induced membrane technique for treating infected bone defects and found that older age and external fixation in the second stage were associated with an increased risk of nonunion. The induced membrane technique is an effective treatment method, and internal fixation can promote bone healing and reduce the need for additional procedures.
BONE & JOINT RESEARCH
(2023)
Article
Engineering, Chemical
Ayesha Ilyas, Loren Timmermans, Maarten Vanierschot, Ilse Smets, Ivo F. J. Vankelecom
Summary: This study investigates the use of spray-modified non-solvent induced phase separation (s-NIPS) to create large patterned PVDF membranes and magnetically induced membrane vibration (MMV) to enhance their anti-fouling properties. The results show that patterned membranes reduce fouling rate and increase critical flux, while membrane vibration further improves anti-fouling potential and delays irreversible fouling.
JOURNAL OF MEMBRANE SCIENCE
(2022)
Article
Environmental Sciences
S. Mariraj Mohan, S. Nagalakshmi
Summary: In this study, the reduction of fouling in Conventional Membrane Bioreactor (C-MBR) and Modified Membrane Bioreactor (M-MBR) was compared through incorporated modification. The introduction of Self-forming dynamic membrane (SFDM) in M-MBR successfully reduced fouling and prolonged the operation time.
JOURNAL OF ENVIRONMENTAL MANAGEMENT
(2022)
Article
Biotechnology & Applied Microbiology
Vasiliki Kolliopoulos, Marley J. Dewey, Maxwell Polanek, Hui Xu, Brendan A. C. Harley
Summary: Craniomaxillofacial (CMF) bone injuries are difficult to heal naturally. Researchers are developing a mineralized collagen scaffold that mimics the features of bone tissue and promotes bone formation. By incorporating placental-derived products into the scaffold, the regenerative potential can be enhanced.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2022)
Article
Critical Care Medicine
Mahircan Demir, Muhammed Cuneyd Gunay, Ibrahim Faruk Adiguzel, Varol Sahinturk
Summary: The treatment of large segmental bone defects is a challenging and time-consuming process. The induced membrane technique, which involves a two-step procedure of filling the defect with bone cement and then removing it and replacing it with cancellous bone autograft, is commonly used in this treatment. This study investigates the effects of adding antibiotics to the bone cement on the induced membrane. The results show that antibiotics added to the cement have negative effects on the membrane, and using antibiotic-free cement may be a better choice in aseptic nonunions.
INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED
(2023)
Article
Environmental Sciences
Adem Yurtsever, Erkan Basaran, Deniz Ucar, Erkan Sahinkaya
Summary: The study investigated the robustness of AnDMBR for synthetic textile wastewater treatment, finding that in the absence of sulfate addition, the removal rate of total COD and filtered COD was 91% and 93% respectively, but decreased to 79% after sulfate addition. The suspended solids concentration in textile wastewater was low, while the dye removal rate was high.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Engineering, Biomedical
Xirui Jing, Chao Xu, Weijie Su, Qiuyue Ding, Bing Ye, Yanlin Su, Keda Yu, Lian Zeng, Xu Yang, Yanzhen Qu, Kaifang Chen, Tingfang Sun, Zhiqiang Luo, Xiaodong Guo
Summary: The study proposes a biomaterial that can induce neural network reconstruction and bone regeneration, with high antibacterial activity. The material achieves strong antibacterial effects through phototherapy and photodynamic treatments, promoting neural cell migration and secretion, thus facilitating innervated bone regeneration.
ADVANCED HEALTHCARE MATERIALS
(2023)
Article
Critical Care Medicine
Cesar Angel Pesciallo, German Garabano, Tamara Dainotto, Glenda Ernst
Summary: The study aimed to describe the outcomes of using induced membrane technique with a high proportion of allograft (up to 64%) to treat infected femoral and tibial segmental bone defects, showing similar union and failure rates compared to series with lower allograft proportions.
INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED
(2021)
Article
Surgery
YouLiang Ren, Lei Liu, Dong Sun, ZhengDong Zhang, Meng Li, Xu Lan, JiangDong Ni, Ming-Ming Yan, Wei Huang, Zi-Ming Liu, AQin Peng, YanLong Zhang, Nan Jiang, KeGuan Song, ZhiPeng Huang, Qing Bi, Jun Zhang, Qun Yang, Jun Yang, Yi Liu, Wei Fu, XiaoBin Tian, YuanZheng Wang, WanRun Zhong, XingHua Song, Abuduxukuer Abudurexiti, ZhiLin Xia, Qing Jiang, HongFei Shi, XiMing Liu, GuoDong Wang, YunSheng Hu, YunFei Zhang, GuoYong Yin, Jin Fan, ShiQing Feng, XianHu Zhou, ZhengDao Li, WenBin He, Jason Weeks, Edward M. Schwarz, Stephen L. Kates, Lei Huang, YiMin Chai, Bin Yu, Zhao Xie, ZhongLiang Deng, Chao Xie
Summary: This study conducted a comprehensive epidemiological analysis of post-traumatic related limb osteomyelitis (PTRLO) in China. The infection rate of PTRLO gradually increased over time, and both Gram-positive and Gram-negative pathogens showed an increase in infection rate. The most prevalent pathogens were Methicillin-sensitive Staphylococcus aureus (MSSA), Methicillin-resistant Staphylococcus aureus (MRSA), Enterococcus faecalis (E. faecalis), and Staphylococcus epidermidis (S. epidermidis) among Gram-positive strains, and Pseudomonas Aeruginosa, Enterobacter cloacae, Escherichia coli, Acinetobacter Baumannii, and Klebsiella Pneumoniae among Gram-negative strains. Opened-fracture, hypoproteinemia, and multiple fractures were identified as high-risk factors for polymicrobial infection.
INTERNATIONAL JOURNAL OF SURGERY
(2023)
Review
Agricultural Engineering
Thanh Ngoc-Dan Cao, Xuan-Thanh Bui, Linh-Thy Le, Bao-Trong Dang, Duyen Phuc-Hanh Tran, Thi-Kim-Quyen Vo, Huu-Tuan Tran, Thanh-Binh Nguyen, Hussnain Mukhtar, Shu-Yuan Pan, Sunita Varjani, Huu Hao Ngo, Thi-Dieu-Hien Vo
Summary: The discharged saline wastewater has a severe impact on the aquatic environment due to the limited treatment performance of many wastewater treatment techniques. Membrane bioreactor (MBR) processes, on the other hand, have shown potential in treating saline wastewater under different salinity levels depending on the adaptation of the microbial community. This study systematically reviews the application of MBR in the treatment of saline wastewater, focusing on microbial structure and treatment efficiencies. The concept of carbon dioxide capture and storage is also proposed for MBR-based saline wastewater treatment technologies to achieve zero emission targets in the circular economy.
BIORESOURCE TECHNOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Helen Willcockson, Huseyin Ozkan, Jose Valdes-Fernandez, Liubov Arbeeva, Esra Mucahit, Layla Musawwir, Lola B. B. Hooper, Froilan Granero-Molto, Felipe Prosper, Lara Longobardi
Summary: This study investigated the role of Ccr2 in osteoblasts in the progression of post-traumatic osteoarthritis (PTOA) and pain. Early inactivation of Ccr2 in osteoblasts delayed cartilage damage and matrix degeneration, as well as DMM-induced bone thickness. Late deletion had less evident improvements. Our findings suggest that Ccr2 in osteoblasts contributes to PTOA progression and pain.