Activation of PI3K signaling prevents aminoglycoside-induced hair cell death in the murine cochlea

Initiating Differentiation in Immortalized Multipotent Otic Progenitor Cells

(2016) Jadali Azadeh et al.   Jove-Journal of Visualized Experiments

C-MYC Transcriptionally Amplifies SOX2 Target Genes to Regulate Self-Renewal in Multipotent Otic Progenitor Cells

(2015) Kelvin Y. Kwan et al.   Stem Cell Reports

Growth factors have a protective effect on neomycin-induced hair cell loss

(2014) Xiangxin Lou et al.   CELL BIOLOGY INTERNATIONAL

PTEN regulation of the proliferation and differentiation of auditory progenitors through the PTEN/PI3K/Akt-signaling pathway in mice

(2014) Chen Sun et al.   NEUROREPORT

Spontaneous regeneration of cochlear supporting cells after neonatal ablation ensures hearing in the adult mouse

(2014) Marcia M. Mellado Lagarde et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mutations in PIK3R1 Cause SHORT Syndrome

(2013) David A. Dyment et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Lead roles for supporting actors: Critical functions of inner ear supporting cells

(2013) Elyssa L. Monzack et al.   HEARING RESEARCH

Inner ear supporting cells protect hair cells by secreting HSP70

(2013) Lindsey A. May et al.   JOURNAL OF CLINICAL INVESTIGATION

Insulin-like growth factor 1 inhibits hair cell apoptosis and promotes the cell cycle of supporting cells by activating different downstream cascades after pharmacological hair cell injury in neonatal mice

(2013) Yushi Hayashi et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Conditional Deletion of Pten Leads to Defects in Nerve Innervation and Neuronal Survival in Inner Ear Development

(2013) Hyung Jin Kim et al.   PLoS One

Genomic Rearrangements of PTEN in Prostate Cancer

(2013) Sopheap Phin et al.   Frontiers in Oncology

PI3K signalling: the path to discovery and understanding

(2012) Bart Vanhaesebroeck et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Simvastatin protects auditory hair cells from gentamicin-induced toxicity and activates Akt signaling in vitro

(2011) Yves Brand et al.   BMC NEUROSCIENCE

Insulin-Like Growth Factor Signaling Regulates the Timing of Sensory Cell Differentiation in the Mouse Cochlea

(2011) T. Okano et al.   JOURNAL OF NEUROSCIENCE

Functional Hair Cell Mechanotransducer Channels Are Required for Aminoglycoside Ototoxicity

(2011) Abdelrahman Alharazneh et al.   PLoS One

Protein Kinase D Is Implicated in the Reversible Commitment to Differentiation in Primary Cultures of Mouse Keratinocytes

(2010) Azadeh Jadali et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of phosphatase and tensin homolog in the development of the mammalian auditory system

(2010) Youyi Dong et al.   NEUROREPORT

Phosphatase and tensin homolog deleted on chromosome 10 regulates sensory cell proliferation and differentiation of hair bundles in the mammalian cochlea

(2010) Y. Dong et al.   NEUROSCIENCE

Rapamycin suppresses seizures and neuronal hypertrophy in a mouse model of cortical dysplasia

(2009) M. C. Ljungberg et al.   Disease Models & Mechanisms

Dexamethasone protects auditory hair cells against TNFα-initiated apoptosis via activation of PI3K/Akt and NFκB signaling

(2009) Scott M. Haake et al.   HEARING RESEARCH

PTEN attenuates PIP3/Akt signaling in the cochlea of the aging CBA/J mouse

(2009) Su-Hua Sha et al.   HEARING RESEARCH

Trafficking of Systemic Fluorescent Gentamicin into the Cochlea and Hair Cells

(2009) Qi Wang et al.   JARO-JOURNAL OF THE ASSOCIATION FOR RESEARCH IN OTOLARYNGOLOGY

A robust and high-throughput Cre reporting and characterization system for the whole mouse brain

(2009) Linda Madisen et al.   NATURE NEUROSCIENCE

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

PTEN and the PI3-Kinase Pathway in Cancer

(2008) Nader Chalhoub et al.   Annual Review of Pathology-Mechanisms of Disease

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

(2008) Da Wei Huang et al.   NUCLEIC ACIDS RESEARCH

The PTEN–PI3K pathway: of feedbacks and cross-talks

(2008) A Carracedo et al.   ONCOGENE