Lesinurad Combined With Allopurinol: A Randomized, Double-Blind, Placebo-Controlled Study in Gout Patients With an Inadequate Response to Standard-of-Care Allopurinol (a US-Based Study)

An open-label, 6-month study of allopurinol safety in gout: The LASSO study

(2015) Michael A. Becker et al.   SEMINARS IN ARTHRITIS AND RHEUMATISM

Pharmacokinetics, pharmacodynamics, and safety of lesinurad, a selective uric acid reabsorption inhibitor, in healthy adult males

(2015) Zancong Shen et al.   Drug Design Development and Therapy

Uricosuric drugs

(2014) Mary H. Bach et al.   CURRENT OPINION IN RHEUMATOLOGY

Improving cardiovascular and renal outcomes in gout: what should we target?

(2014) Pascal Richette et al.   Nature Reviews Rheumatology

Optimizing current treatment of gout

(2014) Frances Rees et al.   Nature Reviews Rheumatology

Pharmacodynamic, pharmacokinetic and tolerability evaluation of concomitant administration of lesinurad and febuxostat in gout patients with hyperuricaemia

(2014) Roy Fleischmann et al.   RHEUMATOLOGY

Tophaceous gout and high level of hyperuricaemia are both associated with increased risk of mortality in patients with gout

(2013) Fernando Perez-Ruiz et al.   ANNALS OF THE RHEUMATIC DISEASES

Randomized Controlled Trial of Febuxostat Versus Allopurinol or Placebo in Individuals with Higher Urinary Uric Acid Excretion and Calcium Stones

(2013) D. S. Goldfarb et al.   Clinical Journal of the American Society of Nephrology

The pathophysiology of hyperuricaemia and its possible relationship to cardiovascular disease, morbidity and mortality

(2013) David Gustafsson et al.   BMC Nephrology

Renal Transport of Uric Acid: Evolving Concepts and Uncertainties

(2012) Ion Alexandru Bobulescu et al.   ADVANCES IN CHRONIC KIDNEY DISEASE

2012 American College of Rheumatology guidelines for management of gout. Part 1: Systematic nonpharmacologic and pharmacologic therapeutic approaches to hyperuricemia

(2012) Dinesh Khanna et al.   ARTHRITIS CARE & RESEARCH

Risk factors associated with renal lithiasis during uricosuric treatment of hyperuricemia in patients with Gout

(2010) Fernando Perez-Ruiz et al.   ARTHRITIS CARE & RESEARCH

The urate-lowering efficacy and safety of febuxostat in the treatment of the hyperuricemia of gout: the CONFIRMS trial

(2010) Michael A Becker et al.   ARTHRITIS RESEARCH & THERAPY

Febuxostat in the treatment of gout: 5-yr findings of the FOCUS efficacy and safety study

(2009) H. R. Schumacher et al.   RHEUMATOLOGY

Febuxostat: a new treatment for hyperuricaemia in gout

(2009) N. L. Edwards   RHEUMATOLOGY

Effects of febuxostat versus allopurinol and placebo in reducing serum urate in subjects with hyperuricemia and gout: A 28-week, phase III, randomized, double-blind, parallel-group trial

(2008) H. RALPH Schumacher et al.   ARTHRITIS AND RHEUMATISM

Analytical approaches to reporting long-term clinical trial data

(2008) Kim A. Papp et al.   CURRENT MEDICAL RESEARCH AND OPINION