Long Intergenic Noncoding RNAs Mediate the Human Chondrocyte Inflammatory Response and Are Differentially Expressed in Osteoarthritis Cartilage

Expression profile of long noncoding RNAs in cartilage from knee osteoarthritis patients

(2015) M. Fu et al.   OSTEOARTHRITIS AND CARTILAGE

Human Immunodeficiency Virus Type 1 Enhancer-binding Protein 3 Is Essential for the Expression of Asparagine-linked Glycosylation 2 in the Regulation of Osteoblast and Chondrocyte Differentiation

(2014) Katsuyuki Imamura et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TPCA-1 Is a Direct Dual Inhibitor of STAT3 and NF- B and Regresses Mutant EGFR-Associated Human Non-Small Cell Lung Cancers

(2014) J. Nan et al.   MOLECULAR CANCER THERAPEUTICS

An atlas of active enhancers across human cell types and tissues

(2014) Robin Andersson et al.   NATURE

Epigenetics of articular cartilage in knee and hip OA

(2014) John Loughlin et al.   Nature Reviews Rheumatology

The hallmarks of osteoarthritis and the potential to develop personalised disease-modifying pharmacological therapeutics

(2014) D.P. Tonge et al.   OSTEOARTHRITIS AND CARTILAGE

Long non-coding RNAs in the regulation of the immune response

(2014) James A. Heward et al.   TRENDS IN IMMUNOLOGY

p50-associated COX-2 extragenic RNA (PACER) activates COX-2 gene expression by occluding repressive NF-κB complexes

(2014) Michal Krawczyk et al.   eLife

Expression and regulation of intergenic long noncoding RNAs during T cell development and differentiation

(2013) Gangqing Hu et al.   NATURE IMMUNOLOGY

GENCODE: The reference human genome annotation for The ENCODE Project

(2012) J. Harrow et al.   GENOME RESEARCH

Modular regulatory principles of large non-coding RNAs

(2012) Mitchell Guttman et al.   NATURE

Identification of the pathogenic pathways in osteoarthritic hip cartilage: commonality and discord between hip and knee OA

(2012) Y. Xu et al.   OSTEOARTHRITIS AND CARTILAGE

Integrative annotation of human large intergenic noncoding RNAs reveals global properties and specific subclasses

(2011) M. N. Cabili et al.   GENES & DEVELOPMENT

Molecular Mechanisms of Long Noncoding RNAs

(2011) Kevin C. Wang et al.   MOLECULAR CELL

Inhibition of IGF-1 Signalling Enhances the Apoptotic Effect of AS602868, an IKK2 Inhibitor, in Multiple Myeloma Cell Lines

(2011) Ines Tagoug et al.   PLoS One

Long noncoding RNAs in cell biology

(2011) Michael B. Clark et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Transcribed dark matter: meaning or myth?

(2010) C. P. Ponting et al.   HUMAN MOLECULAR GENETICS

Resolution of Inflammation in Murine Autoimmune Arthritis Is Disrupted by Cyclooxygenase-2 Inhibition and Restored by Prostaglandin E2-Mediated Lipoxin A4 Production

(2010) M. M. Y. Chan et al.   JOURNAL OF IMMUNOLOGY

Role of proinflammatory cytokines in the pathophysiology of osteoarthritis

(2010) Mohit Kapoor et al.   Nature Reviews Rheumatology

Elevated expression of interleukin-7 receptor in inflamed joints mediates interleukin-7-induced immune activation in rheumatoid arthritis

(2009) Sarita A. Y. Hartgring et al.   ARTHRITIS AND RHEUMATISM

Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals

(2009) Mitchell Guttman et al.   NATURE

Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression

(2009) Ahmad M. Khalil et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Developments in the clinical understanding of osteoarthritis

(2009) David T Felson   ARTHRITIS RESEARCH & THERAPY

Protective effects of licofelone, a 5-lipoxygenase and cyclo-oxygenase inhibitor, versus naproxen on cartilage loss in knee osteoarthritis: a first multicentre clinical trial using quantitative MRI

(2008) J-P Raynauld et al.   ANNALS OF THE RHEUMATIC DISEASES

P38 MAP kinase inhibitors as potential therapeutics for the treatment of joint degeneration and pain associated with osteoarthritis

(2008) Kimberly K Brown et al.   Journal of Inflammation-London

Evaluation of a Photographic Chondropathy Score (PCS) for pathological samples in a study of inflammation in tibiofemoral osteoarthritis

(2008) D.A. Walsh et al.   OSTEOARTHRITIS AND CARTILAGE

The identification of differentially expressed microRNA in osteoarthritic tissue that modulate the production of TNF-α and MMP13

(2008) S.W. Jones et al.   OSTEOARTHRITIS AND CARTILAGE

microRNAs and the immune response

(2008) Mark A. Lindsay   TRENDS IN IMMUNOLOGY

Human articular chondrocytes produce IL-7 and respond to IL-7 with increased production of matrix metalloproteinase-13

(2008) David Long et al.   ARTHRITIS RESEARCH & THERAPY