Public- and Private-Sector Contributions to the Research and Development of the Most Transformational Drugs in the Past 25 Years

Innovation in the pharmaceutical industry: New estimates of R&D costs

(2016) Joseph A. DiMasi et al.   JOURNAL OF HEALTH ECONOMICS

Where do new medicines originate from in the EU?

(2014) Helene Lincker et al.   NATURE REVIEWS DRUG DISCOVERY

An Improved Approach To Measuring Drug Innovation Finds Steady Rates Of First-In-Class Pharmaceuticals, 1987–2011

(2013) Michael Lanthier et al.   HEALTH AFFAIRS

The most transformative drugs of the past 25 years: a survey of physicians

(2013) Aaron S. Kesselheim et al.   NATURE REVIEWS DRUG DISCOVERY

What Are The Respective Roles Of The Public And Private Sectors In Pharmaceutical Innovation?

(2011) Bhaven N. Sampat et al.   HEALTH AFFAIRS

The Role of Public-Sector Research in the Discovery of Drugs and Vaccines

(2011) Ashley J. Stevens et al.   NEW ENGLAND JOURNAL OF MEDICINE

Trends in Risks Associated With New Drug Development: Success Rates for Investigational Drugs

(2010) J A DiMasi et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

The importance of new companies for drug discovery: origins of a decade of new drugs

(2010) Robert Kneller   NATURE REVIEWS DRUG DISCOVERY

Assessing the Impact of Protocol Design Changes on Clinical Trial Performance

(2008) Kenneth A Getz et al.   AMERICAN JOURNAL OF THERAPEUTICS