Targeted Inhibition of the miR-199a/214 Cluster by CRISPR Interference Augments the Tumor Tropism of Human Induced Pluripotent Stem Cell-Derived Neural Stem Cells under Hypoxic Condition

Manufacturing of AcMNPV baculovirus vectors to enable gene therapy trials

(2016) Timothy Weixin Kwang et al.   Molecular Therapy-Methods & Clinical Development

CRISPR/cas9, a novel genomic tool to knock down microRNA in vitro and in vivo

(2016) Hong Chang et al.   Scientific Reports

Using artificial microRNA sponges to achieve microRNA loss-of-function in cancer cells

(2015) Felix Chang Tay et al.   ADVANCED DRUG DELIVERY REVIEWS

miR-214 as a Key Hub that Controls Cancer Networks: Small Player, Multiple Functions

(2015) Elisa Penna et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Yeast Actin-Related Protein ARP6 Negatively RegulatesAgrobacterium-Mediated Transformation of Yeast Cell

(2015) Yumei Luo et al.   Biomed Research International

Integrative Analysis of CRISPR/Cas9 Target Sites in the HumanHBBGene

(2015) Yumei Luo et al.   Biomed Research International

A Double-Switch Cell Fusion-Inducible Transgene Expression System for Neural Stem Cell-Based Antiglioma Gene Therapy

(2015) Yumei Luo et al.   Stem Cells International

Uniparental disomy of the entire X chromosome in Turner syndrome patient-specific induced pluripotent stem cells

(2015) Yumei Luo et al.   Cell Discovery

Induced Pluripotent Stem Cell-Derived Neural Stem Cells Transduced with Baculovirus Encoding CD40 Ligand for Immunogene Therapy in Mouse Models of Breast Cancer

(2014) Detu Zhu et al.   HUMAN GENE THERAPY

Targeting non-coding RNAs with the CRISPR/Cas9 system in human cell lines

(2014) Tsui-Ting Ho et al.   NUCLEIC ACIDS RESEARCH

The UCSC Genome Browser database: 2015 update

(2014) Kate R. Rosenbloom et al.   NUCLEIC ACIDS RESEARCH

Sequence-specific inhibition of microRNA via CRISPR/CRISPRi system

(2014) Yicheng Zhao et al.   Scientific Reports

High-resolution chromosomal microarray analysis of early-stage human embryonic stem cells reveals an association between X chromosome instability and skewed X inactivation

(2014) Yumei Luo et al.   Cell and Bioscience

Combinatorial Control of Transgene Expression by Hypoxia-Responsive Promoter and MicroRNA Regulation for Neural Stem Cell-Based Cancer Therapy

(2014) Yumei Luo et al.   Biomed Research International

Repurposing CRISPR as an RNA-Guided Platform for Sequence-Specific Control of Gene Expression

(2013) Lei S. Qi et al.   CELL

Inhibition of neuronal nitric oxide synthase activity promotes migration of human-induced pluripotent stem cell-derived neural stem cells toward cancer cells

(2013) Can Chen et al.   JOURNAL OF NEUROCHEMISTRY

Systemic Delivery of Fusogenic Membrane Glycoprotein-expressing Neural Stem Cells to Selectively Kill Tumor Cells

(2013) Detu Zhu et al.   MOLECULAR THERAPY

CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering

(2013) Prashant Mali et al.   NATURE BIOTECHNOLOGY

DNA targeting specificity of RNA-guided Cas9 nucleases

(2013) Patrick D Hsu et al.   NATURE BIOTECHNOLOGY

Genome engineering using the CRISPR-Cas9 system

(2013) F Ann Ran et al.   Nature Protocols

Chromosomal deletions and inversions mediated by TALENs and CRISPR/Cas in zebrafish

(2013) An Xiao et al.   NUCLEIC ACIDS RESEARCH

RNA-Guided Human Genome Engineering via Cas9

(2013) P. Mali et al.   SCIENCE

Multiplex Genome Engineering Using CRISPR/Cas Systems

(2013) L. Cong et al.   SCIENCE

Neural Stem Cell-Mediated Enzyme/Prodrug Therapy for Glioma: Preclinical Studies

(2013) K. S. Aboody et al.   Science Translational Medicine

Tumor Tropism of Intravenously Injected Human-Induced Pluripotent Stem Cell-Derived Neural Stem Cells and Their Gene Therapy Application in a Metastatic Breast Cancer Model

(2012) Jing Yang et al.   STEM CELLS

MicroRNA-10b pleiotropically regulates invasion, angiogenicity and apoptosis of tumor cells resembling mesenchymal subtype of glioblastoma multiforme

(2012) J Lin et al.   Cell Death & Disease

Glioma Gene Therapy Using Induced Pluripotent Stem Cell Derived Neural Stem Cells

(2011) Esther Xingwei Lee et al.   MOLECULAR PHARMACEUTICS

Regulation of Axl receptor tyrosine kinase expression by miR-34a and miR-199a/b in solid cancer

(2011) G Mudduluru et al.   ONCOGENE

MicroRNAs Impair MET-Mediated Invasive Growth

(2008) C. Migliore et al.   CANCER RESEARCH

MicroRNAmiR-199a*Regulates theMETProto-oncogene and the Downstream Extracellular Signal-regulated Kinase 2 (ERK2)

(2008) Seonhoe Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neural Stem Cell Tropism to Glioma: Critical Role of Tumor Hypoxia

(2008) D. Zhao et al.   MOLECULAR CANCER RESEARCH

Twist-1 regulates the miR-199a/214 cluster during development

(2008) Y.-B. Lee et al.   NUCLEIC ACIDS RESEARCH