Dynamic regulation of neutrophil polarity and migration by the heterotrimeric G protein subunits Gαi-GTP and Gβγ

A Chemical Biology Approach Demonstrates G Protein βγ Subunits Are Sufficient to Mediate Directional Neutrophil Chemotaxis

(2014) Chinmay R. Surve et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

P-Rex1 directly activates RhoG to regulate GPCR-driven Rac signalling and actin polarity in neutrophils

(2014) G. Damoulakis et al.   JOURNAL OF CELL SCIENCE

Subcellular optogenetic inhibition of G proteins generates signaling gradients and cell migration

(2014) Patrick R. O'Neill et al.   MOLECULAR BIOLOGY OF THE CELL

PKCβII acts downstream of chemoattractant receptors and mTORC2 to regulate cAMP production and myosin II activity in neutrophils

(2014) Lunhua Liu et al.   MOLECULAR BIOLOGY OF THE CELL

A Gβγ Effector, ElmoE, Transduces GPCR Signaling to the Actin Network during Chemotaxis

(2012) Jianshe Yan et al.   DEVELOPMENTAL CELL

Uropod elongation is a common final step in leukocyte extravasation through inflamed vessels

(2012) Young-Min Hyun et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Chemokines and the Signaling Modules Regulating Integrin Affinity

(2012) Alessio Montresor et al.   Frontiers in Immunology

Conformational changes in the G protein Gs induced by the β2 adrenergic receptor

(2011) Ka Young Chung et al.   NATURE

mTORC2 Regulates Neutrophil Chemotaxis in a cAMP- and RhoA-Dependent Fashion

(2010) Lunhua Liu et al.   DEVELOPMENTAL CELL

Cells navigate with a local-excitation, global-inhibition-biased excitable network

(2010) Y. Xiong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Random versus directionally persistent cell migration

(2009) Ryan J. Petrie et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Navigating through models of chemotaxis

(2008) Pablo A Iglesias et al.   CURRENT OPINION IN CELL BIOLOGY

Protein Kinase A Regulates 3-Phosphatidylinositide Dynamics during Platelet-derived Growth Factor-induced Membrane Ruffling and Chemotaxis

(2008) Paula B. Deming et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Spatial Distribution of Protein Kinase A Activity during Cell Migration Is Mediated by A-kinase Anchoring Protein AKAP Lbc

(2008) Adriana A. Paulucci-Holthauzen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY