Loss of epithelial Gq and G11 signaling inhibits TGF production but promotes IL-33-mediated macrophage polarization and emphysema
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Title
Loss of epithelial Gq and G11 signaling inhibits TGF production but promotes IL-33-mediated macrophage polarization and emphysema
Authors
Keywords
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Journal
Science Signaling
Volume 9, Issue 451, Pages ra104-ra104
Publisher
American Association for the Advancement of Science (AAAS)
Online
2016-10-26
DOI
10.1126/scisignal.aad5568
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Related references
Note: Only part of the references are listed.- Gαq signalling: The new and the old
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- TGF-β limits IL-33 production and promotes the resolution of colitis through regulation of macrophage function
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- Integrin v 5-Mediated TGF- Activation by Airway Smooth Muscle Cells in Asthma
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- Latent TGF-β structure and activation
- (2011) Minlong Shi et al. NATURE
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- Lysophosphatidic Acid Induces αvβ6 Integrin-Mediated TGF-β Activation via the LPA2 Receptor and the Small G Protein Gαq
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- Transforming Growth Factor-β Receptor-3 Is Associated with Pulmonary Emphysema
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- Mice that lack activity of v 6- and v 8-integrins reproduce the abnormalities of Tgfb1- and Tgfb3-null mice
- (2009) P. Aluwihare et al. JOURNAL OF CELL SCIENCE
- IL-33 Amplifies the Polarization of Alternatively Activated Macrophages That Contribute to Airway Inflammation
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- Tryptase activates TGFβ in human airway smooth muscle cells via direct proteolysis
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