Dephosphorylation of the adaptor LAT and phospholipase C–γ by SHP-1 inhibits natural killer cell cytotoxicity
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Title
Dephosphorylation of the adaptor LAT and phospholipase C–γ by SHP-1 inhibits natural killer cell cytotoxicity
Authors
Keywords
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Journal
Science Signaling
Volume 9, Issue 429, Pages ra54-ra54
Publisher
American Association for the Advancement of Science (AAAS)
Online
2016-05-25
DOI
10.1126/scisignal.aad6182
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- When ubiquitination meets phosphorylation: a systems biology perspective of EGFR/MAPK signalling
- (2013) Lan K Nguyen et al. Cell Communication and Signaling
- Ubiquitylation-Dependent Negative Regulation of WASp Is Essential for Actin Cytoskeleton Dynamics
- (2012) B. Reicher et al. MOLECULAR AND CELLULAR BIOLOGY
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- SLAM Family Receptors and SAP Adaptors in Immunity
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- 2 Integrin Induces TCR -Syk-Phospholipase C- Phosphorylation and Paxillin-Dependent Granule Polarization in Human NK Cells
- (2011) M. E. March et al. JOURNAL OF IMMUNOLOGY
- Functional Cooperation between the Proteins Nck and ADAP Is Fundamental for Actin Reorganization
- (2011) M. H. Pauker et al. MOLECULAR AND CELLULAR BIOLOGY
- Enhanced T-cell signaling in cells bearing linker for activation of T-cell (LAT) molecules resistant to ubiquitylation
- (2011) L. Balagopalan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cooperative interactions at the SLP-76 complex are critical for actin polymerization
- (2010) Mira Barda-Saad et al. EMBO JOURNAL
- Synergistic Signals for Natural Cytotoxicity Are Required to Overcome Inhibition by c-Cbl Ubiquitin Ligase
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