Eukaryotic replication origins: Strength in flexibility

MCM: one ring to rule them all

(2016) Tom D Deegan et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Replication landscape of the human genome

(2016) Nataliya Petryk et al.   Nature Communications

Dynamic loading and redistribution of the Mcm2-7 helicase complex through the cell cycle

(2015) S. K. Powell et al.   EMBO JOURNAL

Peaks cloaked in the mist: The landscape of mammalian replication origins

(2015) Olivier Hyrien   JOURNAL OF CELL BIOLOGY

Effects of Transcription Elongation Rate and Xrn2 Exonuclease Activity on RNA Polymerase II Termination Suggest Widespread Kinetic Competition

(2015) Nova Fong et al.   MOLECULAR CELL

Post-licensing Specification of Eukaryotic Replication Origins by Facilitated Mcm2-7 Sliding along DNA

(2015) Julien Gros et al.   MOLECULAR CELL

Structure of the eukaryotic MCM complex at 3.8 Å

(2015) Ningning Li et al.   NATURE

Regulated eukaryotic DNA replication origin firing with purified proteins

(2015) Joseph T. P. Yeeles et al.   NATURE

The contribution of dormant origins to genome stability: From cell biology to human genetics

(2014) Robert C. Alver et al.   DNA REPAIR

Origin plasticity during budding yeast DNA replication in vitro

(2014) J. Gros et al.   EMBO JOURNAL

Prereplicative complexes assembled in vitro support origin-dependent and independent DNA replication

(2014) K. F. On et al.   EMBO JOURNAL

Structural and mechanistic insights into Mcm2–7 double-hexamer assembly and function

(2014) Jingchuan Sun et al.   GENES & DEVELOPMENT

Initiation of DNA Replication from Non-Canonical Sites on an Origin-Depleted Chromosome

(2014) Naomi L. Bogenschutz et al.   PLoS One

Cdc48 and a ubiquitin ligase drive disassembly of the CMG helicase at the end of DNA replication

(2014) Marija Maric et al.   SCIENCE

Polyubiquitylation drives replisome disassembly at the termination of DNA replication

(2014) Sara Priego Moreno et al.   SCIENCE

A conserved MCM single-stranded DNA binding element is essential for replication initiation

(2014) Clifford A Froelich et al.   eLife

Quantitative, Genome-Wide Analysis of Eukaryotic Replication Initiation and Termination

(2013) Sean R. McGuffee et al.   MOLECULAR CELL

Dealing with Pervasive Transcription

(2013) Torben Heick Jensen et al.   MOLECULAR CELL

Extensive transcriptional heterogeneity revealed by isoform profiling

(2013) Vicent Pelechano et al.   NATURE

DNA Replication Timing

(2013) N. Rhind et al.   Cold Spring Harbor Perspectives in Biology

Regulating DNA Replication in Eukarya

(2013) K. Siddiqui et al.   Cold Spring Harbor Perspectives in Biology

Disengaging polymerase: Terminating RNA polymerase II transcription in budding yeast

(2012) Hannah E. Mischo et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

The dynamics of replication licensing in liveCaenorhabditis elegansembryos

(2012) Remi Sonneville et al.   JOURNAL OF CELL BIOLOGY

Highly stable loading of Mcm proteins onto chromatin in living cells requires replication to unload

(2011) Marjorie A. Kuipers et al.   JOURNAL OF CELL BIOLOGY

Conserved nucleosome positioning defines replication origins

(2010) M. L. Eaton et al.   GENES & DEVELOPMENT

Relicensing of Transcriptionally Inactivated Replication Origins in Budding Yeast

(2010) Marko Lõoke et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Concerted Loading of Mcm2–7 Double Hexamers around DNA during DNA Replication Origin Licensing

(2009) Dirk Remus et al.   CELL

Eukaryotic DNA replication control: Lock and load, then fire

(2009) Dirk Remus et al.   CURRENT OPINION IN CELL BIOLOGY

DNA replication as a target of the DNA damage checkpoint

(2009) Philip Zegerman et al.   DNA REPAIR

A double-hexameric MCM2-7 complex is loaded onto origin DNA during licensing of eukaryotic DNA replication

(2009) C. Evrin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA