Recent Advance in the Relationship between Excitatory Amino Acid Transporters and Parkinson’s Disease

Exercise-Mediated Increase in Nigral Tyrosine Hydroxylase Is Accompanied by Increased Nigral GFR-α1 and EAAC1 Expression in Aging Rats

(2015) Jennifer C. Arnold et al.   ACS Chemical Neuroscience

Targeting glutamatergic synapses in Parkinson's disease

(2015) Fabrizio Gardoni et al.   CURRENT OPINION IN PHARMACOLOGY

Risk of Parkinson's disease following anxiety disorders: a nationwide population-based cohort study

(2015) C.-H. Lin et al.   EUROPEAN JOURNAL OF NEUROLOGY

Conditional Deletion of the Glutamate Transporter GLT-1 Reveals That Astrocytic GLT-1 Protects against Fatal Epilepsy While Neuronal GLT-1 Contributes Significantly to Glutamate Uptake into Synaptosomes

(2015) G. T. Petr et al.   JOURNAL OF NEUROSCIENCE

Surface diffusion of astrocytic glutamate transporters shapes synaptic transmission

(2015) Ciaran Murphy-Royal et al.   NATURE NEUROSCIENCE

Alterations in the motor cortical and striatal glutamatergic system and d-serine levels in the bilateral 6-hydroxydopamine rat model for Parkinson's disease

(2015) Anissa El Arfani et al.   NEUROCHEMISTRY INTERNATIONAL

Alpha-synuclein modulates NR2B-containing NMDA receptors and decreases their levels after rotenone exposure

(2015) Laura Navarria et al.   NEUROCHEMISTRY INTERNATIONAL

Ceftriaxone prevents and reverses behavioral and neuronal deficits in an MPTP-induced animal model of Parkinson's disease dementia

(2015) Chao-Yu Hsu et al.   NEUROPHARMACOLOGY

Astroglial Glutamate Transporter Deficiency Increases Synaptic Excitability and Leads to Pathological Repetitive Behaviors in Mice

(2015) Tomomi Aida et al.   NEUROPSYCHOPHARMACOLOGY

Effects of ceftriaxone on the behavioral and neuronal changes in an MPTP-induced Parkinson's disease rat model

(2014) Shih-Chun Ho et al.   BEHAVIOURAL BRAIN RESEARCH

Glutamatergic pathways as a target for the treatment of dyskinesias in Parkinson's disease: Figure 1

(2014) M. Angela Cenci   BIOCHEMICAL SOCIETY TRANSACTIONS

Small-molecule activator of glutamate transporter EAAT2 translation provides neuroprotection

(2014) Qiongman Kong et al.   JOURNAL OF CLINICAL INVESTIGATION

Dopamine denervation of the prefrontal cortex increases expression of the astrocytic glutamate transporter GLT-1

(2014) Peter J. Vollbrecht et al.   JOURNAL OF NEUROCHEMISTRY

Inflammatory response in Parkinson’s disease (Review)

(2014) JUNQIANG YAN et al.   Molecular Medicine Reports

Ceftriaxone Protects Astrocytes from MPP+ via Suppression of NF-κB/JNK/c-Jun Signaling

(2014) Yunlong Zhang et al.   MOLECULAR NEUROBIOLOGY

Progressive Parkinsonism by acute dysfunction of excitatory amino acid transporters in the rat substantia nigra

(2014) Maxime Assous et al.   NEUROBIOLOGY OF DISEASE

The effects of the β-lactam antibiotic, ceftriaxone, on forepaw stepping and l-DOPA-induced dyskinesia in a rodent model of Parkinson’s disease

(2014) John E. Kelsey et al.   PSYCHOPHARMACOLOGY

Rhythmic oscillations of the microRNA miR-96-5p play a neuroprotective role by indirectly regulating glutathione levels

(2014) Chisato Kinoshita et al.   Nature Communications

Coupled ion binding and structural transitions along the transport cycle of glutamate transporters

(2014) Grégory Verdon et al.   eLife

Inhibition of microRNA-181 Reduces Forebrain Ischemia-Induced Neuronal Loss

(2013) Jeong-mi Moon et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

A further update on the role of excitotoxicity in the pathogenesis of Parkinson’s disease

(2013) Giulia Ambrosi et al.   JOURNAL OF NEURAL TRANSMISSION

Ceftriaxone increases glutamate uptake and reduces striatal tyrosine hydroxylase loss in 6-OHDA Parkinson's model

(2013) Tanya Chotibut et al.   MOLECULAR NEUROBIOLOGY

Mechanisms of Glutamate Transport

(2013) Robert J. Vandenberg et al.   PHYSIOLOGICAL REVIEWS

Excitotoxicity: Bridge to various triggers in neurodegenerative disorders

(2012) Ankita Mehta et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Transient striatal GLT-1 blockade increases EAAC1 expression, glutamate reuptake, and decreases tyrosine hydroxylase phosphorylation at ser19

(2012) Michael F. Salvatore et al.   EXPERIMENTAL NEUROLOGY

The Density of EAAC1 (EAAT3) Glutamate Transporters Expressed by Neurons in the Mammalian CNS

(2012) S. Holmseth et al.   JOURNAL OF NEUROSCIENCE

Relationship between increase in astrocytic GLT-1 glutamate transport and late-LTP

(2012) J. D. Pita-Almenar et al.   LEARNING & MEMORY

Glutamate-based depression GBD

(2012) Dennis J. McCarthy et al.   MEDICAL HYPOTHESES

Crystal structure of an asymmetric trimer of a bacterial glutamate transporter homolog

(2012) Grégory Verdon et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Hippocampal Glutamate Level and Glutamate Aspartate Transporter (GLAST) are Up-Regulated in Senior Rat Associated with Isoflurane-Induced Spatial Learning/Memory Impairment

(2012) Xiangdong Qu et al.   NEUROCHEMICAL RESEARCH

Glutamate Transporters EAAT4 and EAAT5 Are Expressed in Vestibular Hair Cells and Calyx Endings

(2012) Antoine Dalet et al.   PLoS One

Neuropsychiatric Symptoms in Parkinson's Disease with Mild Cognitive Impairment and Dementia

(2012) Iracema Leroi et al.   Parkinsons Disease

Ceftriaxone Ameliorates Motor Deficits and Protects Dopaminergic Neurons in 6-Hydroxydopamine-Lesioned Rats

(2011) T. C. H. Leung et al.   ACS Chemical Neuroscience

Disruption of Eaat2b, a glutamate transporter, results in abnormal motor behaviors in developing zebrafish

(2011) Kelly Anne McKeown et al.   DEVELOPMENTAL BIOLOGY

Nuclear Factor Erythroid 2-Related Factor 2 Facilitates Neuronal Glutathione Synthesis by Upregulating Neuronal Excitatory Amino Acid Transporter 3 Expression

(2011) C. Escartin et al.   JOURNAL OF NEUROSCIENCE

Glutamate and NMDA receptors activation leads to cerebellar dysfunction and impaired motor coordination in unilateral 6-hydroxydopamine lesioned Parkinson’s rat: functional recovery with bone marrow cells, serotonin and GABA

(2011) M. S. Nandhu et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Glutamatergic mechanisms in the dyskinesias induced by pharmacological dopamine replacement and deep brain stimulation for the treatment of Parkinson's disease

(2011) Véronique Sgambato-Faure et al.   PROGRESS IN NEUROBIOLOGY

Shaping the synaptic signal: molecular mobility inside and outside the cleft

(2011) Dmitri A. Rusakov et al.   TRENDS IN NEUROSCIENCES

N-acetylcysteine prevents loss of dopaminergic neurons in theEAAC1−/−mouse

(2010) Ari E. Berman et al.   ANNALS OF NEUROLOGY

Cortical Regulation of Striatal Medium Spiny Neuron Dendritic Remodeling in Parkinsonism: Modulation of Glutamate Release Reverses Dopamine Depletion–Induced Dendritic Spine Loss

(2010) Bonnie G. Garcia et al.   CEREBRAL CORTEX

Time-dependent changes in GLT-1 functioning in striatum of hemi-Parkinson rats

(2010) Ann Massie et al.   NEUROCHEMISTRY INTERNATIONAL

Impaired glutamate homeostasis and programmed cell death in a chronic MPTP mouse model of Parkinson's disease

(2009) G.E. Meredith et al.   EXPERIMENTAL NEUROLOGY

Neuronal Transporters Regulate Glutamate Clearance, NMDA Receptor Activation, and Synaptic Plasticity in the Hippocampus

(2009) A. Scimemi et al.   JOURNAL OF NEUROSCIENCE

Transport mechanism of a bacterial homologue of glutamate transporters

(2009) Nicolas Reyes et al.   NATURE

Enhancement of glutamate uptake in 1-methyl-4-phenylpyridinium-treated astrocytes by trichostatin A

(2009) Jia-Yong Wu et al.   NEUROREPORT

Mechanism of Ceftriaxone Induction of Excitatory Amino Acid Transporter-2 Expression and Glutamate Uptake in Primary Human Astrocytes

(2008) Seok-Geun Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Downregulation of glial glutamate transporters after dopamine denervation in the striatum of 6-hydroxydopamine-lesioned rats

(2008) E.K.Y. Chung et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Preferential vulnerability of mesencephalic dopamine neurons to glutamate transporter dysfunction

(2008) Imane Nafia et al.   JOURNAL OF NEUROCHEMISTRY

Aging: An important factor for the pathogenesis of neurodegenerative diseases

(2008) Tahira Farooqui et al.   MECHANISMS OF AGEING AND DEVELOPMENT