Emerging Role of Spinal Cord TRPV1 in Pain Exacerbation

In Vivo Patch-Clamp Analysis of the Antinociceptive Actions of TRPA1 Activation in the Spinal Dorsal Horn

(2015) Manabu Yamanaka et al.   Molecular Pain

Tmem100 Is a Regulator of TRPA1-TRPV1 Complex and Contributes to Persistent Pain

(2015) Hao-Jui Weng et al.   NEURON

Spinal excitatory mechanisms of pathological pain

(2015) Rohini Kuner   PAIN

Pain-enhancing mechanism through interaction between TRPV1 and anoctamin 1 in sensory neurons

(2015) Yasunori Takayama et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Are Sensory TRP Channels Biological Alarms for Lipid Peroxidation?

(2014) Seung-In Choi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Spinal 5-HT3 Receptors Mediate Descending Facilitation and Contribute to Behavioral Hypersensitivity via a Reciprocal Neuron-Glial Signaling Cascade

(2014) Wei Guo et al.   Molecular Pain

Sensory TRP Channel Interactions with Endogenous Lipids and Their Biological Outcomes

(2014) Sungjae Yoo et al.   MOLECULES

Central Terminal Sensitization of TRPV1 by Descending Serotonergic Facilitation Modulates Chronic Pain

(2014) Yu Shin Kim et al.   NEURON

Synaptic plasticity in pathological pain

(2014) Ceng Luo et al.   TRENDS IN NEUROSCIENCES

Emerging roles of TRPA1 in sensation of oxidative stress and its implications in defense and danger

(2013) SangSeong Kim et al.   ARCHIVES OF PHARMACAL RESEARCH

Resolvins: Endogenously-Generated Potent Painkilling Substances and their Therapeutic Perspectives

(2013) Sungjae Yoo et al.   Current Neuropharmacology

Loss of interneuron LTD and attenuated pyramidal cell LTP inTrpv1andTrpv3KO mice

(2013) Travis E. Brown et al.   HIPPOCAMPUS

Permeation and block of TRPV1 channels by the cationic lidocaine derivative QX-314

(2013) Michelino Puopolo et al.   JOURNAL OF NEUROPHYSIOLOGY

Transition to Persistent Orofacial Pain after Nerve Injury Involves Supraspinal Serotonin Mechanisms

(2013) M. Okubo et al.   JOURNAL OF NEUROSCIENCE

Intrathecal AAV Serotype 9-mediated Delivery of shRNA Against TRPV1 Attenuates Thermal Hyperalgesia in a Mouse Model of Peripheral Nerve Injury

(2013) Takashi Hirai et al.   MOLECULAR THERAPY

TRPV1 channels make major contributions to behavioral hypersensitivity and spontaneous activity in nociceptors after spinal cord injury

(2013) Zizhen Wu et al.   PAIN

Fatty Acid Amide Hydrolase-Dependent Generation of Antinociceptive Drug Metabolites Acting on TRPV1 in the Brain

(2013) David A. Barrière et al.   PLoS One

The functions of TRPA1 and TRPV1: moving away from sensory nerves

(2012) ES Fernandes et al.   BRITISH JOURNAL OF PHARMACOLOGY

The C-Type Natriuretic Peptide Induces Thermal Hyperalgesia through a Noncanonical G  -dependent Modulation of TRPV1 Channel

(2012) L. Loo et al.   JOURNAL OF NEUROSCIENCE

Activation of the cGMP/Protein Kinase G Pathway by Nitric Oxide Can Decrease TRPV1 Activity in Cultured Rat Dorsal Root Ganglion Neurons

(2012) Yunju Jin et al.   KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY

TRPV1 in GABAergic Interneurons Mediates Neuropathic Mechanical Allodynia and Disinhibition of the Nociceptive Circuitry in the Spinal Cord

(2012) Yong Ho Kim et al.   NEURON

Spinal 12-lipoxygenase-derived hepoxilin A3 contributes to inflammatory hyperalgesia via activation of TRPV1 and TRPA1 receptors

(2012) A. M. Gregus et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intrathecal shRNA-AAV9 Inhibits Target Protein Expression in the Spinal Cord and Dorsal Root Ganglia of Adult Mice

(2012) Takashi Hirai et al.   Human Gene Therapy Methods

Presynaptically Localized Cyclic GMP-Dependent Protein Kinase 1 Is a Key Determinant of Spinal Synaptic Potentiation and Pain Hypersensitivity

(2012) Ceng Luo et al.   PLOS BIOLOGY

Plasticity of TRPV1-Expressing Sensory Neurons Mediating Autonomic Dysreflexia Following Spinal Cord Injury

(2012) Leanne M. Ramer et al.   Frontiers in Physiology

Intrathecal Administration of AS1928370, a Transient Receptor Potential Vanilloid 1 Antagonist, Attenuates Mechanical Allodynia in a Mouse Model of Neuropathic Pain

(2011) Tomonari Watabiki et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Capsaicin in the periaqueductal gray induces analgesia via metabotropic glutamate receptor-mediated endocannabinoid retrograde disinhibition

(2011) H-T Liao et al.   BRITISH JOURNAL OF PHARMACOLOGY

TRPA1 ion channel in the spinal dorsal horn as a therapeutic target in central pain hypersensitivity and cutaneous neurogenic inflammation

(2011) Antti Pertovaara et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Preservation of Acute Pain and Efferent Functions Following Intrathecal Resiniferatoxin-Induced Analgesia in Rats

(2011) Mahendra Bishnoi et al.   JOURNAL OF PAIN

Alterations in the emotional and memory behavioral phenotypes of transient receptor potential vanilloid type 1-deficient mice are mediated by changes in expression of 5-HT1A, GABAA, and NMDA receptors

(2011) In-Jee You et al.   NEUROPHARMACOLOGY

Spinal transient receptor potential ankyrin 1 channel contributes to central pain hypersensitivity in various pathophysiological conditions in the rat

(2011) Hong Wei et al.   PAIN

Pirt, a TRPV1 Modulator, Is Required for Histamine-Dependent and -Independent Itch

(2011) Kush N. Patel et al.   PLoS One

Computational functions of neurons and circuits signaling injury: Relationship to pain behavior

(2011) L. M. Mendell   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Emerging roles of resolvins in the resolution of inflammation and pain

(2011) Ru-Rong Ji et al.   TRENDS IN NEUROSCIENCES

TRPA1 mediates spinal antinociception induced by acetaminophen and the cannabinoid Δ9-tetrahydrocannabiorcol

(2011) David A Andersson et al.   Nature Communications

Opioid-Induced Long-Term Potentiation in the Spinal Cord Is a Presynaptic Event

(2010) H.-Y. Zhou et al.   JOURNAL OF NEUROSCIENCE

Resolvins RvE1 and RvD1 attenuate inflammatory pain via central and peripheral actions

(2010) Zhen-Zhong Xu et al.   NATURE MEDICINE

Modulation of inhibitory neurotransmission by the vanilloid receptor type 1 (TRPV1) in organotypically cultured mouse substantia gelatinosa neurons

(2010) Francesco Ferrini et al.   PAIN

TRPV1 in Brain Is Involved in Acetaminophen-Induced Antinociception

(2010) Christophe Mallet et al.   PLoS One

Antagonism of TRPV1 receptors indirectly modulates activity of thermoregulatory neurons in the medial preoptic area of rats

(2009) Steve McGaraughty et al.   BRAIN RESEARCH

Functional Interaction Between TRPV1 and μ-Opioid Receptors in the Descending Antinociceptive Pathway Activates Glutamate Transmission and Induces Analgesia

(2009) Sabatino Maione et al.   JOURNAL OF NEUROPHYSIOLOGY

Roles of cutaneous versus spinal TRPA1 channels in mechanical hypersensitivity in the diabetic or mustard oil-treated non-diabetic rat

(2009) Hong Wei et al.   NEUROPHARMACOLOGY

Selective Targeting of TRPV1 Expressing Sensory Nerve Terminals in the Spinal Cord for Long Lasting Analgesia

(2009) Joseph A. Jeffry et al.   PLoS One

Activation of TRPV1 in the spinal cord by oxidized linoleic acid metabolites contributes to inflammatory hyperalgesia

(2009) A. M. Patwardhan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Supraspinal Glial-Neuronal Interactions Contribute to Descending Pain Facilitation

(2008) F. Wei et al.   JOURNAL OF NEUROSCIENCE

Investigation of TRPV1 loss-of-function phenotypes in transgenic shRNA expressing and knockout mice

(2008) Thomas Christoph et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

TRPV1 Channels Mediate Long-Term Depression at Synapses on Hippocampal Interneurons

(2008) Helen E. Gibson et al.   NEURON