Article
Dermatology
Nagasai C. Adusumilli, Breanne Mordorski, Joshua Nosanchuk, Joel M. Friedman, Adam J. Friedman
Summary: The study suggests that curcumin nanoparticles may serve as a promising adjuvant for sunscreens, reducing UV-induced inflammation and cell apoptosis. In mouse experiments, mice pretreated with curc-np showed less skin erythema and damage after UVB irradiation, demonstrating better anti-inflammatory effects.
EXPERIMENTAL DERMATOLOGY
(2021)
Article
Computer Science, Information Systems
Jack A. Cummins, Vinod E. Nambudiri
Summary: This study utilized natural language processing techniques to analyze comments on Reddit related to skincare topics. By tracking the frequency of discussions and analyzing the content, insights into public health issues were gained. The results showed that the comment frequencies varied over time and demonstrated seasonal patterns, and the sentiment analysis revealed a range of positive sentiments.
INTERNATIONAL JOURNAL OF MEDICAL INFORMATICS
(2022)
Article
Oncology
Lucas W. Thornblade, Ernest Han, Yuman Fong
Summary: Patients with colorectal cancer ovarian metastasis have favorable long-term survival. Survival rates are higher if the tumor is isolated to the ovary or if metachronous to the primary cancer.
INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER
(2021)
Article
Dermatology
Shi Yu Derek Lim, Anthony Teik-Jin Goon, Yung Hian Leow, Tricia Yi Rui Chong, Eugene Sern-Ting Tan, Wei Na Suzanne Cheng
Summary: This study retrospectively analyzed photopatch testing data from the National Skin Centre in Singapore between 2012 and 2021. It found that organic ultraviolet absorbers such as oxybenzone and mexenone remained the most common photoallergens. Testing personal items was valuable for diagnosing photoallergic contact dermatitis.
PHOTODERMATOLOGY PHOTOIMMUNOLOGY & PHOTOMEDICINE
(2023)
Article
Surgery
Robin J. Lurvink, Koen P. Rovers, Emma C. E. Wassenaar, Checca Bakkers, Jacobus W. A. Burger, Geert-Jan M. Creemers, Maartje Los, Floortje Mols, Marinus J. Wiezer, Simon W. Nienhuijs, Djamila Boerma, Ignace H. J. T. de Hingh
Summary: This study prospectively assessed the impact of PPIAC-OX on PROs for CPM patients and found clinically relevant but reversible worsening in patients during treatment, mainly occurring 1 week after the first procedure.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2022)
Article
Chemistry, Medicinal
Audrey Fohlen, Karim Bordji, Eric Assenat, Celine Gongora, Celine Bazille, Jeremy Boulonnais, Mikael Naveau, Cecile Breuil, Elodie A. Peres, Myriam Bernaudin, Boris Guiu
Summary: This study investigated the response of different cell lines to 12 cytotoxic agents, finding that idarubicin was the most cytotoxic to most colorectal cancer cell lines, while gemcitabine was most effective for certain cell lines. Interestingly, commonly used cytotoxic agents in the treatment of colorectal liver metastases showed limited cytotoxicity in the tested cell lines.
Article
Dermatology
Bruno Augusto Alvares, Anna Carolina Miola, Juliano Vilaverde Schimitt, Helio Amante Miot, Luciana Patricia Fernandes Abbade
Summary: The study aimed to evaluate the efficacy of using sunscreen with photolyase compared to regular sunscreen, as well as comparing the combination of topical antioxidants versus placebo in the treatment of advanced photodamage. The results showed no difference in the treatment of advanced photodamage skin between sunscreen with photolyase and regular sunscreen, and topical antioxidants were more efficient in reducing the number of actinic keratoses compared to placebo.
ANAIS BRASILEIROS DE DERMATOLOGIA
(2022)
Article
Dermatology
Min Ah Kim, Yu Chul Jung, Jiyoun Bae, Jaehyoun Ha, Eunjoo Kim
Summary: The study found that consecutively layering sunscreen and makeup can significantly increase the effective sun protection factor, even when the amount of each product used is below the recommended level. This method may compensate for consumers' usual insufficient application of sunscreen, providing additional UV protection.
SKIN RESEARCH AND TECHNOLOGY
(2021)
Article
Pathology
Bruce G. Rottmann, Natalie Patel, Muhammad Ahmed, Yanhong Deng, Maria Ciarleglio, Monika Vyas, Dhanpat Jain, Xuchen Zhang
Summary: This study investigates the prognostic significance of tumor-infiltrating neutrophil (TIN) in colorectal carcinomas (CRCs). The results show that high TIN is associated with higher histological grade, right-sided tumor location, advanced TNM stage, and higher rate of MMR-deficient CRCs. Patients with neutrophil-rich (NR) CRCs have significantly poorer 5-year recurrence-free survival compared to neutrophil-intermediate (NI) or neutrophil-poor (NP) CRCs. High TIN remains an independent risk factor for poor prognosis. NR CRCs are more commonly seen in MMR-deficient CRCs, and MMR-deficient NR CRCs have similar 5-year recurrence-free survival compared to MMR-proficient NR CRCs.
JOURNAL OF CLINICAL PATHOLOGY
(2023)
Review
Dermatology
Flavia Alvim Sant'anna Addor, Carlos Baptista Barcaui, Elimar Elias Gomes, Omar Lupi, Carolina Reato Marcon, Helio Amante Miot
Summary: This review article discusses the current and relevant concepts of photoprotection for dermatological use, including formulation challenges, risks of photoprotective active substances, and the importance of product efficacy. Technical knowledge of sunscreens can assist dermatologists in educating patients on the best photoprotective strategies.
ANAIS BRASILEIROS DE DERMATOLOGIA
(2022)
Article
Medicine, Research & Experimental
Yu Shen, Xin Zhao, Haijian Zhao, Ning Chen, Jian Wang, Haiwen Zhuang, Xiaoyu Zhang
Summary: This study found that enteral nutrition combined with microbial preparations for bowel preparation in elderly patients with colorectal cancer is safe and effective. It improves nutritional status, reduces complications, and facilitates postoperative recovery.
MEDICAL SCIENCE MONITOR
(2022)
Review
Cell Biology
Giulia Russo, Michael Krauss
Summary: Cytokinesis involves the final separation of a mother cell into two daughter cells, with septins playing a crucial role in this process. Septins are recruited to the cleavage furrow early on and undergo constant rearrangement during cytokinetic progression, ultimately concentrating within the intercellular bridge. This concentration of septins at specific sites may support cytokinetic progression by interacting with actin, microtubules, and associated motors.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2021)
Article
Oncology
Jana Halamkova, Lucia Bohovicova, Lucie Pehalova, Roman Gonec, Teodor Stanek, Tomas Kazda, Lucie Moukova, Dagmar Adamkova Krakorova, Sarka Kozakova, Marek Svoboda, Regina Demlova, Igor Kiss
Summary: The association between hypolipidemic drugs and the occurrence of a second primary malignancy in colorectal cancer survivors is not clear. Subgroup analysis shows a lower incidence of secondary neoplasia in statin users, but colorectal cancer patients using hypolipidemic drugs are more likely to develop gastric and bladder cancer. Patients with early-stage colorectal carcinoma who suffered a second cancer have significantly worse survival outcomes if treated with hypolipidemic drugs. Therefore, screening for second primary malignancies in colorectal cancer survivors treated with hypolipidemic drugs should be done more cautiously, especially for gastric and bladder cancer.
Review
Food Science & Technology
Sara Moazzen, Kimberley J. W. van der Sloot, Geertruida H. de Bock, Behrooz Z. Alizadeh
Summary: The study found that high diet quality is associated with reduced risk of colorectal cancer, particularly with low Diet Inflammatory Index score and high Mediterranean Diet Score. However, concerns over inconsistency and imprecision led to the pooled results of all dietary indices being rated as low quality.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2021)
Article
Oncology
Lindy M. Kregting, Ellen M. G. Olthof, Emilie C. H. Breekveldt, Clare A. Aitken, Eveline A. M. Heijnsdijk, Esther Toes-Zoutendijk, Harry J. de Koning, Nicolien T. van Ravesteyn
Summary: There is consistency in the participation of Dutch women in breast, cervical, and colorectal cancer screening programs. Lower concurrent participation rates were observed in urban areas and lower socio-economic status groups.
EUROPEAN JOURNAL OF CANCER
(2022)