Spheroid culture of primary hepatocytes with short fibers as a predictable in vitro model for drug screening

Interactions of Pluronic nanocarriers with 2D and 3D cell cultures: Effects of PEO block length and aggregation state

(2016) Alexandra Arranja et al.   JOURNAL OF CONTROLLED RELEASE

Hepatocyte spheroid culture on fibrous scaffolds with grafted functional ligands as an in vitro model for predicting drug metabolism and hepatotoxicity

(2015) Shili Yan et al.   Acta Biomaterialia

Therapeutic angiogenesis in ischemic muscles after local injection of fragmented fibers with loaded traditional Chinese medicine

(2015) Huiyan Li et al.   Nanoscale

Hepatocyte Cocultures with Endothelial Cells and Fibroblasts on Micropatterned Fibrous Mats to Promote Liver-Specific Functions and Capillary Formation Capabilities

(2014) Yaowen Liu et al.   BIOMACROMOLECULES

Micropatterned Cell–Cell Interactions Enable Functional Encapsulation of Primary Hepatocytes in Hydrogel Microtissues

(2014) Cheri Y. Li et al.   TISSUE ENGINEERING PART A

Long-Term Stability of Primary Rat Hepatocytes in Micropatterned Cocultures

(2013) Okechukwu Ukairo et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

A synthetic nanofibrillar matrix promotes in vitro hepatic differentiation of embryonic stem cells and induced pluripotent stem cells

(2013) T. Yamazoe et al.   JOURNAL OF CELL SCIENCE

Generation of Functional Hepatocyte-Like Cells from Human Pluripotent Stem Cells in a Scalable Suspension Culture

(2013) Massoud Vosough et al.   STEM CELLS AND DEVELOPMENT

3D spheroid culture of hESC/hiPSC-derived hepatocyte-like cells for drug toxicity testing

(2012) Kazuo Takayama et al.   BIOMATERIALS

Biophysical microenvironment and 3D culture physiological relevance

(2012) Amish Asthana et al.   DRUG DISCOVERY TODAY

Prediction of Cytochrome 450 Mediated Drug-Drug Interactions by Three-Dimensional Cultured Hepatocytes

(2012) C. Shen et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Reducing safety-related drug attrition: the use of in vitro pharmacological profiling

(2012) Joanne Bowes et al.   NATURE REVIEWS DRUG DISCOVERY

Nanoporous fibers of type-I collagen coated poly(l-lactic acid) for enhancing primary hepatocyte growth and function

(2012) Ting Wang et al.   Journal of Materials Chemistry B

Rat Primary Hepatocytes Show Enhanced Performance and Sensitivity to Acetaminophen During Three-Dimensional Culture on a Polystyrene Scaffold Designed for Routine Use

(2011) Maaike Schutte et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

Galactosylated cellulosic sponge for multi-well drug safety testing

(2011) Bramasta Nugraha et al.   BIOMATERIALS

Tethered spheroids as an in vitro hepatocyte model for drug safety screening

(2011) Lei Xia et al.   BIOMATERIALS

Furocoumarins affect hepatic cytochrome P450 and renal organic ion transporters in mice

(2011) Xing Wang et al.   TOXICOLOGY LETTERS

Rat hepatocyte aggregate formation on discrete aligned nanofibers of type-I collagen-coated poly(l-lactic acid)

(2010) Zhang-Qi Feng et al.   BIOMATERIALS

Heparin-based hydrogel as a matrix for encapsulation and cultivation of primary hepatocytes

(2010) Mihye Kim et al.   BIOMATERIALS

Prevention of Local Tumor Recurrence Following Surgery Using Low-Dose Chemotherapeutic Polymer Films

(2009) Rong Liu et al.   ANNALS OF SURGICAL ONCOLOGY

Evaluation of a microfluidic based cell culture platform with primary human hepatocytes for the prediction of hepatic clearance in human

(2009) P. Chao et al.   BIOCHEMICAL PHARMACOLOGY

A microfluidic hepatic coculture platform for cell-based drug metabolism studies

(2009) Eric Novik et al.   BIOCHEMICAL PHARMACOLOGY

The effect of nanofibrous galactosylated chitosan scaffolds on the formation of rat primary hepatocyte aggregates and the maintenance of liver function

(2009) Zhang-Qi Feng et al.   BIOMATERIALS

Oxygen-mediated enhancement of primary hepatocyte metabolism, functional polarization, gene expression, and drug clearance

(2009) S. Kidambi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Actin, a Central Player in Cell Shape and Movement

(2009) T. D. Pollard et al.   SCIENCE