Vitamin B6 Prevents Endothelial Dysfunction, Insulin Resistance, and Hepatic Lipid Accumulation inApoe−/−Mice Fed with High-Fat Diet

RosiglitazoneviaPPARγ-dependent suppression of oxidative stress attenuates endothelial dysfunction in rats fed homocysteine thiolactone

(2015) Xu-Hong Yang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Altered distribution of regulatory lymphocytes by oral administration of soy-extracts exerts a hepatoprotective effect alleviating immune mediated liver injury, non-alcoholic steatohepatitis and insulin resistance

(2015) Tawfik Khoury   WORLD JOURNAL OF GASTROENTEROLOGY

Developmental Programming of Nonalcoholic Fatty Liver Disease: The Effect of Early Life Nutrition on Susceptibility and Disease Severity in Later Life

(2015) Minglan Li et al.   Biomed Research International

AMPK activation prevents excess nutrient-induced hepatic lipid accumulation by inhibiting mTORC1 signaling and endoplasmic reticulum stress response

(2014) Hongliang Li et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

BL153 Partially Prevents High-Fat Diet Induced Liver Damage Probably via Inhibition of Lipid Accumulation, Inflammation, and Oxidative Stress

(2014) Jian Wang et al.   Oxidative Medicine and Cellular Longevity

Plasmatic higher levels of homocysteine in Non-alcoholic fatty liver disease (NAFLD)

(2013) Sylene Coutinho Rampche de Carvalho et al.   Nutrition Journal

Identification of Akt-independent Regulation of Hepatic Lipogenesis by Mammalian Target of Rapamycin (mTOR) Complex 2

(2012) Minsheng Yuan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Marginal Vitamin B-6 Deficiency Decreases Plasma (n-3) and (n-6) PUFA Concentrations in Healthy Men and Women

(2012) Mei Zhao et al.   JOURNAL OF NUTRITION

Activation of AMP-activated protein kinase α2 by nicotine instigates formation of abdominal aortic aneurysms in mice in vivo

(2012) Shuangxi Wang et al.   NATURE MEDICINE

Chronic Exposure to Nicotine Enhances Insulin Sensitivity through α7 Nicotinic Acetylcholine Receptor-STAT3 Pathway

(2012) Tian-Ying Xu et al.   PLoS One

Molecular mechanisms and the role of saturated fatty acids in the progression of non-alcoholic fatty liver disease

(2012) Alexandra K. Leamy et al.   PROGRESS IN LIPID RESEARCH

Vitamin B6: a challenging link between nutrition and inflammation in CVD

(2011) Valentina Lotto et al.   BRITISH JOURNAL OF NUTRITION

Inhibition of the AMP-Activated Protein Kinase-α2 Accentuates Agonist-Induced Vascular Smooth Muscle Contraction and High Blood Pressure in Mice

(2011) Shuangxi Wang et al.   HYPERTENSION

High fat diet-induced non alcoholic fatty liver disease in rats is associated with hyperhomocysteinemia caused by down regulation of the transsulphuration pathway

(2011) Elena Bravo et al.   Lipids in Health and Disease

Apoptosis in nonalcoholic fatty liver disease: diagnostic and therapeutic implications

(2011) Naim Alkhouri et al.   Expert Review of Gastroenterology & Hepatology

AMPKα2 Deletion Causes Aberrant Expression and Activation of NAD(P)H Oxidase and Consequent Endothelial Dysfunction In Vivo

(2010) Shuangxi Wang et al.   CIRCULATION RESEARCH

A Branched-Chain Amino Acid-Related Metabolic Signature that Differentiates Obese and Lean Humans and Contributes to Insulin Resistance

(2009) Christopher B. Newgard et al.   Cell Metabolism

In Vivo Activation of AMP-Activated Protein Kinase Attenuates Diabetes-Enhanced Degradation of GTP Cyclohydrolase I

(2009) S. Wang et al.   DIABETES

Na+/H+exchanger mediates TNF-α-induced hepatocyte apoptosis via the calpain-dependent degradation of Bcl-xL

(2009) Zhan Liu et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

A Mathematical Model Gives Insights into the Effects of Vitamin B-6 Deficiency on 1-Carbon and Glutathione Metabolism

(2009) H. Frederik Nijhout et al.   JOURNAL OF NUTRITION

From chronic overnutrition to insulin resistance: The role of fat-storing capacity and inflammation

(2009) L. Lionetti et al.   NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES

Fatty acids and glucolipotoxicity in the pathogenesis of Type 2 diabetes

(2008) Miriam Cnop   BIOCHEMICAL SOCIETY TRANSACTIONS

Na+/H+ exchanger is required for hyperglycaemia-induced endothelial dysfunction via calcium-dependent calpain

(2008) S. Wang et al.   CARDIOVASCULAR RESEARCH

Acute Inhibition of Guanosine Triphosphate Cyclohydrolase 1 Uncouples Endothelial Nitric Oxide Synthase and Elevates Blood Pressure

(2008) Shuangxi Wang et al.   HYPERTENSION

Molecular Mechanisms of Lipotoxicity in Nonalcoholic Fatty Liver Disease

(2008) Harmeet Malhi et al.   SEMINARS IN LIVER DISEASE