Extracellular Vesicle-Associated Transitory Cell Wall Components and Their Impact on the Interaction of Fungi with Host Cells

The glycolytic enzyme enolase represents a plasminogen-binding protein on the surface of a wide variety of medically important fungal species

(2016) Jana Funk et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Interactions of fungal pathogens with phagocytes

(2016) Lars P. Erwig et al.   NATURE REVIEWS MICROBIOLOGY

Antibody Binding Alters the Characteristics and Contents of Extracellular Vesicles Released by Histoplasma capsulatum

(2016) Ludmila Matos Baltazar et al.   mSphere

Cell wall proteome of pathogenic fungi

(2015) Justyna Karkowska-Kuleta et al.   ACTA BIOCHIMICA POLONICA

Surfaceome of pathogenic yeasts, Candida parapsilosis and Candida tropicalis, revealed with the use of cell surface shaving method and shotgun proteomic approach

(2015) Justyna Karkowska-Kuleta et al.   ACTA BIOCHIMICA POLONICA

β-(1→3),(1→6)-Glucans: medicinal activities, characterization, biosynthesis and new horizons

(2015) Nicole Dalonso et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Fibronectin-, vitronectin- and laminin-binding proteins at the cell walls of Candida parapsilosis and Candida tropicalis pathogenic yeasts

(2015) Andrzej Kozik et al.   BMC MICROBIOLOGY

Candida albicansis able to use M cells as a portal of entry across the intestinal barrierin vitro

(2015) Sandrine Albac et al.   CELLULAR MICROBIOLOGY

C-type lectins in immunity: recent developments

(2015) Ivy M Dambuza et al.   CURRENT OPINION IN IMMUNOLOGY

Immune Interactions with Pathogenic and Commensal Fungi: A Two-Way Street

(2015) David M. Underhill et al.   IMMUNITY

Cryptococcal Heat Shock Protein 70 Homolog Ssa1 Contributes to Pulmonary Expansion ofCryptococcus neoformansduring the Afferent Phase of the Immune Response by Promoting Macrophage M2 Polarization

(2015) Alison J. Eastman et al.   JOURNAL OF IMMUNOLOGY

Candida albicans cell shaving uncovers new proteins involved in cell wall integrity, yeast to hypha transition, stress response and host–pathogen interaction

(2015) Ana Gil-Bona et al.   Journal of Proteomics

Quantitative proteomic study of Aspergillus Fumigatus secretome revealed deamidation of secretory enzymes

(2015) Sunil S. Adav et al.   Journal of Proteomics

Through the wall: extracellular vesicles in Gram-positive bacteria, mycobacteria and fungi

(2015) Lisa Brown et al.   NATURE REVIEWS MICROBIOLOGY

Cell Wall Remodeling Enzymes Modulate Fungal Cell Wall Elasticity and Osmotic Stress Resistance

(2015) Iuliana V. Ene et al.   mBio

Extracellular vesicles from Paracoccidioides pathogenic species transport polysaccharide and expose ligands for DC-SIGN receptors

(2015) Roberta Peres da Silva et al.   Scientific Reports

Chitin Recognition via Chitotriosidase Promotes Pathologic Type-2 Helper T Cell Responses to Cryptococcal Infection

(2015) Darin L. Wiesner et al.   PLoS Pathogens

Traveling into Outer Space: Unanswered Questions about Fungal Extracellular Vesicles

(2015) Marcio L. Rodrigues et al.   PLoS Pathogens

CR3 and Dectin-1 Collaborate in Macrophage Cytokine Response through Association on Lipid Rafts and Activation of Syk-JNK-AP-1 Pathway

(2015) Juin-Hua Huang et al.   PLoS Pathogens

An introduction to protein moonlighting: Table 1

(2014) Constance J. Jeffery   BIOCHEMICAL SOCIETY TRANSACTIONS

Compositional and immunobiological analyses of extracellular vesicles released byCandida albicans

(2014) Gabriele Vargas et al.   CELLULAR MICROBIOLOGY

Interaction of Cryptococcus neoformans Extracellular Vesicles with the Cell Wall

(2014) Julie M. Wolf et al.   EUKARYOTIC CELL

Proteomics Unravels Extracellular Vesicles as Carriers of Classical Cytoplasmic Proteins in Candida albicans

(2014) Ana Gil-Bona et al.   JOURNAL OF PROTEOME RESEARCH

Immunological basis of anti-Candidavaccines focused on synthetically prepared cell wall mannan-derived manno-oligomers

(2014) Lucia Paulovičová et al.   MICROBIOLOGY AND IMMUNOLOGY

Candida albicans Uses the Surface Protein Gpm1 to Attach to Human Endothelial Cells and to Keratinocytes via the Adhesive Protein Vitronectin

(2014) Crisanto M. Lopez et al.   PLoS One

Exploiting fungal cell wall components in vaccines

(2014) Stuart M. Levitz et al.   Seminars in Immunopathology

Extracellular enolase of Candida albicans is involved in colonization of mammalian intestinal epithelium

(2014) Richard C. Silva et al.   Frontiers in Cellular and Infection Microbiology

Fungal glycans and the innate immune recognition

(2014) Eliana Barreto-Bergter et al.   Frontiers in Cellular and Infection Microbiology

Diagnostic value of immunoglobulin G antibodies against Candida enolase and fructose-bisphosphate aldolase for candidemia

(2013) Fang-qiu Li et al.   BMC INFECTIOUS DISEASES

Vesicular mechanisms of traffic of fungal molecules to the extracellular space

(2013) Marcio L Rodrigues et al.   CURRENT OPINION IN MICROBIOLOGY

The heat shock protein (Hsp) 70 of Cryptococcus neoformans is associated with the fungal cell surface and influences the interaction between yeast and host cells

(2013) Carolina P. Silveira et al.   FUNGAL GENETICS AND BIOLOGY

Where Do They Come from and Where Do They Go: Candidates for Regulating Extracellular Vesicle Formation in Fungi

(2013) Débora Oliveira et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The impact of proteomics on the understanding of functions and biogenesis of fungal extracellular vesicles

(2013) Marcio L. Rodrigues et al.   Journal of Proteomics

Glucanase Induces Filamentation of the Fungal Pathogen Candida albicans

(2013) Hongbin Xu et al.   PLoS One

News from the Fungal Front: Wall Proteome Dynamics and Host–Pathogen Interplay

(2013) Clemens J. Heilmann et al.   PLoS Pathogens

Chitin-Like Molecules Associate with Cryptococcus neoformans Glucuronoxylomannan To Form a Glycan Complex with Previously Unknown Properties

(2012) Caroline L. Ramos et al.   EUKARYOTIC CELL

Surface Stress Induces a Conserved Cell Wall Stress Response in the Pathogenic Fungus Candida albicans

(2012) Clemens J. Heilmann et al.   EUKARYOTIC CELL

Surface-expressed enolase contributes to the adhesion of Paracoccidioides brasiliensis to host cells

(2012) Caroline Maria Marcos et al.   FEMS YEAST RESEARCH

Architecture and Biosynthesis of the Saccharomyces cerevisiae Cell Wall

(2012) P. Orlean   GENETICS

MBL-Mediated Opsonophagocytosis of Candida albicans by Human Neutrophils Is Coupled with Intracellular Dectin-1-Triggered ROS Production

(2012) Dongsheng Li et al.   PLoS One

LL37 and hBD-3 elevate the β-1,3-exoglucanase activity ofCandida albicansXog1p, resulting in reduced fungal adhesion to plastic

(2011) Hao-Teng Chang et al.   BIOCHEMICAL JOURNAL

The role of Dectin-1 in the host defence against fungal infections

(2011) Rebecca A Drummond et al.   CURRENT OPINION IN MICROBIOLOGY

C-type lectin receptors and cytokines in fungal immunity

(2011) Simon Vautier et al.   CYTOKINE

The Pathogenic Fungus Paracoccidioides brasiliensis Exports Extracellular Vesicles Containing Highly Immunogenic α-Galactosyl Epitopes

(2011) Milene C. Vallejo et al.   EUKARYOTIC CELL

Identification, characterization and regulation studies of the aconitase of Paracoccidioides brasiliensis

(2011) Wesley de A. Brito et al.   Fungal Biology

Vesicular transport systems in fungi

(2011) Marcio L Rodrigues et al.   Future Microbiology

Activation of the innate immune receptor Dectin-1 upon formation of a ‘phagocytic synapse’

(2011) Helen S. Goodridge et al.   NATURE

Molecular determinants of the interaction between human high molecular weight kininogen and Candida albicans cell wall: Identification of kininogen-binding proteins on fungal cell wall and mapping the cell wall-binding regions on kininogen molecule

(2011) Justyna Karkowska-Kuleta et al.   PEPTIDES

Histoplasma capsulatum Heat-Shock 60 Orchestrates the Adaptation of the Fungus to Temperature Stress

(2011) Allan Jefferson Guimarães et al.   PLoS One

Human Antimicrobial Peptide LL-37 Inhibits Adhesion of Candida albicans by Interacting with Yeast Cell-Wall Carbohydrates

(2011) Pei-Wen Tsai et al.   PLoS One

Characterizing the Role of Cell-Wall β-1,3-Exoglucanase Xog1p in Candida albicans Adhesion by the Human Antimicrobial Peptide LL-37

(2011) Pei-Wen Tsai et al.   PLoS One

Immunisation with the glycolytic enzyme enolase confers effective protection against Candida albicans infection in mice

(2011) Wen qing Li et al.   VACCINE

The Paracoccidioides Cell Wall: Past and Present Layers Toward Understanding Interaction with the Host

(2011) Rosana Puccia et al.   Frontiers in Microbiology

1,3-β-d-Glucan synthase of Paracoccidioides brasiliensis: recombinant protein, expression and cytolocalization in the yeast and mycelium phases

(2010) Patrícia Kott Tomazett et al.   Fungal Biology

Agglutination ofHistoplasma capsulatumby IgG Monoclonal Antibodies against Hsp60 Impacts Macrophage Effector Functions

(2010) Allan Jefferson Guimarães et al.   INFECTION AND IMMUNITY

Paracoccidioides brasiliensis Enolase Is a Surface Protein That Binds Plasminogen and Mediates Interaction of Yeast Forms with Host Cells

(2010) S. V. Nogueira et al.   INFECTION AND IMMUNITY

Extracellular Vesicles from Cryptococcus neoformans Modulate Macrophage Functions

(2010) D. L. Oliveira et al.   INFECTION AND IMMUNITY

Host Cell Invasion and Virulence Mediated by Candida albicans Ssa1

(2010) Jianing N. Sun et al.   PLoS Pathogens

The malate synthase of Paracoccidioides brasiliensis is a linked surface protein that behaves as an anchorless adhesin

(2009) Benedito da Silva Neto et al.   BMC MICROBIOLOGY

Role for Chitin and Chitooligomers in the Capsular Architecture ofCryptococcus neoformans

(2009) Fernanda L. Fonseca et al.   EUKARYOTIC CELL

Monoclonal Antibodies to Heat Shock Protein 60 Alter the Pathogenesis of Histoplasma capsulatum

(2009) A. J. Guimaraes et al.   INFECTION AND IMMUNITY

Surface-Associated Plasminogen Binding of Cryptococcus neoformans Promotes Extracellular Matrix Invasion

(2009) Jamal Stie et al.   PLoS One

Vesicular transport inHistoplasma capsulatum: an effective mechanism for trans-cell wall transfer of proteins and lipids in ascomycetes

(2008) Priscila Costa Albuquerque et al.   CELLULAR MICROBIOLOGY

When Signaling Pathways Collide: Positive and Negative Regulation of Toll-like Receptor Signal Transduction

(2008) Luke A.J. O'Neill   IMMUNITY

A Candida albicans Mannoprotein Deprived of Its Mannan Moiety Is Efficiently Taken Up and Processed by Human Dendritic Cells and Induces T-Cell Activation without Stimulating Proinflammatory Cytokine Production

(2008) D. Pietrella et al.   INFECTION AND IMMUNITY

Dectin-1 and its role in antifungal immunity

(2008) Matti Kimberg et al.   MEDICAL MYCOLOGY

Candida albicans Cell Wall Proteins

(2008) W. L. Chaffin   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Hypoxic conditions and iron restriction affect the cell-wall proteome of Candida albicans grown under vagina-simulative conditions

(2008) Grazyna J. Sosinska et al.   MICROBIOLOGY-SGM

Polarized growth in fungi – interplay between the cytoskeleton, positional markers and membrane domains

(2008) Reinhard Fischer et al.   MOLECULAR MICROBIOLOGY

A study of the Candida albicans cell wall proteome

(2008) Luis Castillo et al.   PROTEOMICS

Serological proteome analysis to identify systemic candidiasis patients in the intensive care unit: Analytical, diagnostic and prognostic validation of anti-Candida enolase antibodies on quantitative clinical platforms

(2008) Aida Pitarch et al.   Proteomics Clinical Applications