Tethering of an E3 ligase by PCM1 regulates the abundance of centrosomal KIAA0586/Talpid3 and promotes ciliogenesis

Mutations in KIAA0586 Cause Lethal Ciliopathies Ranging from a Hydrolethalus Phenotype to Short-Rib Polydactyly Syndrome

(2015) Caroline Alby et al.   AMERICAN JOURNAL OF HUMAN GENETICS

KIAA0586is Mutated in Joubert Syndrome

(2015) Ruxandra Bachmann-Gagescu et al.   HUMAN MUTATION

The E3 ubiquitin ligase Mib1 regulates Plk4 and centriole biogenesis

(2015) L.  ajanek et al.   JOURNAL OF CELL SCIENCE

Mutations in human homologue of chickentalpid3gene (KIAA0586) cause a hybrid ciliopathy with overlapping features of Jeune and Joubert syndromes

(2015) May Christine V Malicdan et al.   JOURNAL OF MEDICAL GENETICS

TALPID3 controls centrosome and cell polarity and the human ortholog KIAA0586 is mutated in Joubert syndrome (JBTS23)

(2015) Louise A Stephen et al.   eLife

Functional genome-wide siRNA screen identifies KIAA0586 as mutated in Joubert syndrome

(2015) Susanne Roosing et al.   eLife

Centriolar satellites: key mediators of centrosome functions

(2014) Maxim A. X. Tollenaere et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The CP110-interacting proteins Talpid3 and Cep290 play overlapping and distinct roles in cilia assembly

(2014) Tetsuo Kobayashi et al.   JOURNAL OF CELL BIOLOGY

Assembling a primary cilium

(2013) Sehyun Kim et al.   CURRENT OPINION IN CELL BIOLOGY

A new cellular stress response that triggers centriolar satellite reorganization and ciliogenesis

(2013) Bine H Villumsen et al.   EMBO JOURNAL

Bardet–Biedl syndrome proteins control the cilia length through regulation of actin polymerization

(2013) Victor Hernandez-Hernandez et al.   HUMAN MOLECULAR GENETICS

Rab8a and Rab8b are essential for several apical transport pathways but insufficient for ciliogenesis

(2013) T. Sato et al.   JOURNAL OF CELL SCIENCE

The novel centriolar satellite protein SSX2IP targets Cep290 to the ciliary transition zone

(2013) Maren Klinger et al.   MOLECULAR BIOLOGY OF THE CELL

Primary Cilia Are Lost in Preinvasive and Invasive Prostate Cancer

(2013) Nadia B. Hassounah et al.   PLoS One

The E3 Ligase Mind Bomb-1 (Mib1) Modulates Delta-Notch Signaling to Control Neurogenesis and Gliogenesis in the Developing Spinal Cord

(2012) Kyungjoon Kang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cep164 mediates vesicular docking to the mother centriole during early steps of ciliogenesis

(2012) Kerstin N. Schmidt et al.   JOURNAL OF CELL BIOLOGY

The centriolar satellite proteins Cep72 and Cep290 interact and are required for recruitment of BBS proteins to the cilium

(2012) Timothy R. Stowe et al.   MOLECULAR BIOLOGY OF THE CELL

CEP90 Is Required for the Assembly and Centrosomal Accumulation of Centriolar Satellites, Which Is Essential for Primary Cilia Formation

(2012) Kyeongmi Kim et al.   PLoS One

Generation of mice with functional inactivation of talpid3, a gene first identified in chicken

(2011) F. Bangs et al.   DEVELOPMENT

Mindbomb 1, an E3 ubiquitin ligase, forms a complex with RYK to activate Wnt/β-catenin signaling

(2011) Jason D. Berndt et al.   JOURNAL OF CELL BIOLOGY

Regulating the transition from centriole to basal body

(2011) Tetsuo Kobayashi et al.   JOURNAL OF CELL BIOLOGY

Centriolar satellites are assembly points for proteins implicated in human ciliopathies, including oral-facial-digital syndrome 1

(2011) C. A. M. Lopes et al.   JOURNAL OF CELL SCIENCE

The pericentriolar satellite protein CEP90 is crucial for integrity of the mitotic spindle pole

(2011) K. Kim et al.   JOURNAL OF CELL SCIENCE

Ciliogenesis: building the cell's antenna

(2011) Hiroaki Ishikawa et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Ofd1, a Human Disease Gene, Regulates the Length and Distal Structure of Centrioles

(2010) Veena Singla et al.   DEVELOPMENTAL CELL

Control of ciliogenesis by FOR20, a novel centrosome and pericentriolar satellite protein

(2010) F. Sedjai et al.   JOURNAL OF CELL SCIENCE

Recruitment of PCM1 to the Centrosome by the Cooperative Action of DISC1 and BBS4

(2008) Atsushi Kamiya et al.   ARCHIVES OF GENERAL PSYCHIATRY

CEP290 interacts with the centriolar satellite component PCM-1 and is required for Rab8 localization to the primary cilium

(2008) Joon Kim et al.   HUMAN MOLECULAR GENETICS