Angiopoietin receptor Tie2 is required for vein specification and maintenance via regulating COUP-TFII

Choose your destiny: Make a cell fate decision with COUP-TFII

(2016) San-Pin Wu et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

APJ Regulates Parallel Alignment of Arteries and Veins in the Skin

(2015) Hiroyasu Kidoya et al.   DEVELOPMENTAL CELL

Rapamycin improves TIE2-mutated venous malformation in murine model and human subjects

(2015) Elisa Boscolo et al.   JOURNAL OF CLINICAL INVESTIGATION

Genetic Dissection of Tie Pathway in Mouse Lymphatic Maturation and Valve Development

(2014) Bin Shen et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

SoxF factors and Notch regulate nr2f2 gene expression during venous differentiation in zebrafish

(2014) Matthew R. Swift et al.   DEVELOPMENTAL BIOLOGY

A lymphatic defect causes ocular hypertension and glaucoma in mice

(2014) Benjamin R. Thomson et al.   JOURNAL OF CLINICAL INVESTIGATION

Targeting VE-PTP activates TIE2 and stabilizes the ocular vasculature

(2014) Jikui Shen et al.   JOURNAL OF CLINICAL INVESTIGATION

Arteries are formed by vein-derived endothelial tip cells

(2014) Cong Xu et al.   Nature Communications

Myocardium-derived angiopoietin-1 is essential for coronary vein formation in the developing heart

(2014) Yoh Arita et al.   Nature Communications

Endothelial RAF1/ERK activation regulates arterial morphogenesis

(2013) Y. Deng et al.   BLOOD

ETS Factors Regulate Vegf-Dependent Arterial Specification

(2013) Joshua D. Wythe et al.   DEVELOPMENTAL CELL

The Neuropilin 1 Cytoplasmic Domain Is Required for VEGF-A-Dependent Arteriogenesis

(2013) Anthony Lanahan et al.   DEVELOPMENTAL CELL

Sox17 is indispensable for acquisition and maintenance of arterial identity

(2013) Monica Corada et al.   Nature Communications

The Wnt/β-Catenin Pathway Modulates Vascular Remodeling and Specification by Upregulating Dll4/Notch Signaling

(2010) Monica Corada et al.   DEVELOPMENTAL CELL

The nuclear hormone receptor Coup-TFII is required for the initiation and early maintenance of Prox1 expression in lymphatic endothelial cells

(2010) R. S. Srinivasan et al.   GENES & DEVELOPMENT

ERK1/2-Akt1 crosstalk regulates arteriogenesis in mice and zebrafish

(2010) Bin Ren et al.   JOURNAL OF CLINICAL INVESTIGATION

Direct transcriptional regulation of neuropilin-2 by COUP-TFII modulates multiple steps in murine lymphatic vessel development

(2010) Fu-Jung Lin et al.   JOURNAL OF CLINICAL INVESTIGATION

Ephrin-B2 controls VEGF-induced angiogenesis and lymphangiogenesis

(2010) Yingdi Wang et al.   NATURE

Control of vascular morphogenesis and homeostasis through the angiopoietin–Tie system

(2009) Hellmut G. Augustin et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Angiopoietins assemble distinct Tie2 signalling complexes in endothelial cell–cell and cell–matrix contacts

(2008) Pipsa Saharinen et al.   NATURE CELL BIOLOGY

Somatic mutations in angiopoietin receptor gene TEK cause solitary and multiple sporadic venous malformations

(2008) Nisha Limaye et al.   NATURE GENETICS