Loss of MeCP2 disrupts cell autonomous and autocrine BDNF signaling in mouse glutamatergic neurons

Autocrine Action of BDNF on Dendrite Development of Adult-Born Hippocampal Neurons

(2015) L. Wang et al.   JOURNAL OF NEUROSCIENCE

Genotype-specific effects of Mecp2 loss-of-function on morphology of Layer V pyramidal neurons in heterozygous female Rett syndrome model mice

(2015) Leslie Rietveld et al.   Frontiers in Cellular Neuroscience

A BDNF loop-domain mimetic acutely reverses spontaneous apneas and respiratory abnormalities during behavioral arousal in a mouse model of Rett syndrome

(2014) M. Kron et al.   Disease Models & Mechanisms

A Critical and Cell-Autonomous Role for MeCP2 in Synaptic Scaling Up

(2012) M. P. Blackman et al.   JOURNAL OF NEUROSCIENCE

MeCP2 Is Critical for Maintaining Mature Neuronal Networks and Global Brain Anatomy during Late Stages of Postnatal Brain Development and in the Mature Adult Brain

(2012) M. V. C. Nguyen et al.   JOURNAL OF NEUROSCIENCE

A TrkB Small Molecule Partial Agonist Rescues TrkB Phosphorylation Deficits and Improves Respiratory Function in a Mouse Model of Rett Syndrome

(2012) D. A. Schmid et al.   JOURNAL OF NEUROSCIENCE

Un lien inattendu entre maladie de Huntington et syndrome de Rett

(2012) Jean-Christophe Roux et al.   M S-MEDECINE SCIENCES

Neurotrophin regulation of neural circuit development and function

(2012) Hyungju Park et al.   NATURE REVIEWS NEUROSCIENCE

Fingolimod, a sphingosine-1 phosphate receptor modulator, increases BDNF levels and improves symptoms of a mouse model of Rett syndrome

(2012) R. Deogracias et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activity-dependent BDNF release and TRPC signaling is impaired in hippocampal neurons of Mecp2 mutant mice

(2012) W. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

7,8-dihydroxyflavone exhibits therapeutic efficacy in a mouse model of Rett syndrome

(2011) Rebecca A. Johnson et al.   JOURNAL OF APPLIED PHYSIOLOGY

Identification of a low–molecular weight TrkB antagonist with anxiolytic and antidepressant activity in mice

(2011) Maxime Cazorla et al.   JOURNAL OF CLINICAL INVESTIGATION

High Cleavage Efficiency of a 2A Peptide Derived from Porcine Teschovirus-1 in Human Cell Lines, Zebrafish and Mice

(2011) Jin Hee Kim et al.   PLoS One

Self-amplifying autocrine actions of BDNF in axon development

(2011) P.-L. Cheng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Adult Neural Function Requires MeCP2

(2011) C. M. McGraw et al.   SCIENCE

Early Environmental Enrichment Moderates the Behavioral and Synaptic Phenotype of MeCP2 Null Mice

(2010) Giuseppina Lonetti et al.   BIOLOGICAL PSYCHIATRY

Abnormalities of cell packing density and dendritic complexity in the MeCP2 A140V mouse model of Rett syndrome/X-linked mental retardation

(2010) Garilyn M Jentarra et al.   BMC NEUROSCIENCE

Regulation of Dendritic Development by BDNF Requires Activation of CRTC1 by Glutamate

(2010) Charles Finsterwald et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Small molecule BDNF mimetics activate TrkB signaling and prevent neuronal degeneration in rodents

(2010) Stephen M. Massa et al.   JOURNAL OF CLINICAL INVESTIGATION

Exogenous Brain-Derived Neurotrophic Factor Rescues Synaptic Dysfunction in Mecp2-Null Mice

(2010) D. D. Kline et al.   JOURNAL OF NEUROSCIENCE

Dysfunction in GABA signalling mediates autism-like stereotypies and Rett syndrome phenotypes

(2010) Hsiao-Tuan Chao et al.   NATURE

A selective TrkB agonist with potent neurotrophic activities by 7,8-dihydroxyflavone

(2010) S.-W. Jang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MeCP2 functions largely cell-autonomously, but also non-cell-autonomously, in neuronal maturation and dendritic arborization of cortical pyramidal neurons

(2009) Noriyuki Kishi et al.   EXPERIMENTAL NEUROLOGY

Widespread changes in dendritic and axonal morphology inMecp2-mutant mouse models of rett syndrome: Evidence for disruption of neuronal networks

(2009) Pavel V. Belichenko et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Matrix-Dependent Local Retention of Secretory Vesicle Cargo in Cortical Neurons

(2009) J. de Wit et al.   JOURNAL OF NEUROSCIENCE

Bdnf overexpression in hippocampal neurons prevents dendritic atrophy caused by Rett-associated MECP2 mutations

(2009) Jennifer L. Larimore et al.   NEUROBIOLOGY OF DISEASE

Partial reversal of Rett Syndrome-like symptoms in MeCP2 mutant mice

(2009) Daniela Tropea et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

BDNF signaling in the formation, maturation and plasticity of glutamatergic and GABAergic synapses

(2009) Kurt Gottmann et al.   EXPERIMENTAL BRAIN RESEARCH

Environmental enrichment ameliorates a motor coordination deficit in a mouse model of Rett syndromeMecp2gene dosage effects and BDNF expression

(2008) Mari Kondo et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Targeted delivery of an Mecp2 transgene to forebrain neurons improves the behavior of female Mecp2-deficient mice

(2008) D. G.M. Jugloff et al.   HUMAN MOLECULAR GENETICS

MeCP2, a Key Contributor to Neurological Disease, Activates and Represses Transcription

(2008) M. Chahrour et al.   SCIENCE