Murine Fam65b forms ring-like structures at the base of stereocilia critical for mechanosensory hair cell function

The elusive mechanotransduction machinery of hair cells

(2015) Bo Zhao et al.   CURRENT OPINION IN NEUROBIOLOGY

Front-signal-dependent accumulation of the RHOA inhibitor FAM65B at leading edges polarizes neutrophils

(2015) K. Gao et al.   JOURNAL OF CELL SCIENCE

New treatment options for hearing loss

(2015) Ulrich Müller et al.   NATURE REVIEWS DRUG DISCOVERY

The proteome of mouse vestibular hair bundles over development

(2015) Jocelyn F. Krey et al.   Scientific Data

Hair-bundle proteomes of avian and mammalian inner-ear utricles

(2015) Phillip A. Wilmarth et al.   Scientific Data

Characterization and regulation of an additional actin-filament-binding site in large isoforms of the stereocilia actin-bundling protein espin

(2014) L. Zheng et al.   JOURNAL OF CELL SCIENCE

TMIE Is an Essential Component of the Mechanotransduction Machinery of Cochlear Hair Cells

(2014) Bo Zhao et al.   NEURON

The Physiology of Mechanoelectrical Transduction Channels in Hearing

(2014) Robert Fettiplace et al.   PHYSIOLOGICAL REVIEWS

Little evidence that FAM65B belongs to the family of phox homology (PX) and bin/amphiphysin/rvs (BAR) domain-containing proteins

(2014) Rohan D. Teasdale et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reply to Teasdale and Collins: N-terminal region of FAM65B bears similarity to the PX–BAR module of SNX33

(2014) Amjad Farooq et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

FAM65B is a membrane-associated protein of hair cell stereocilia required for hearing

(2014) Oscar Diaz-Horta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CLIC5 stabilizes membrane-actin filament linkages at the base of hair cell stereocilia in a molecular complex with radixin, taperin, and myosin VI

(2013) Felipe T. Salles et al.   Cytoskeleton

Molecular architecture of the chick vestibular hair bundle

(2013) Jung-Bum Shin et al.   NATURE NEUROSCIENCE

TMHS Is an Integral Component of the Mechanotransduction Machinery of Cochlear Hair Cells

(2012) Wei Xiong et al.   CELL

Fam65b Is a New Transcriptional Target of FOXO1 That Regulates RhoA Signaling for T Lymphocyte Migration

(2012) P. Rougerie et al.   JOURNAL OF IMMUNOLOGY

Large Membrane Domains in Hair Bundles Specify Spatially Constricted Radixin Activation

(2012) H. Zhao et al.   JOURNAL OF NEUROSCIENCE

Localization of PDZD7 to the Stereocilia Ankle-Link Associates this Scaffolding Protein with the Usher Syndrome Protein Network

(2012) M. Grati et al.   JOURNAL OF NEUROSCIENCE

Dual-objective STORM reveals three-dimensional filament organization in the actin cytoskeleton

(2012) Ke Xu et al.   NATURE METHODS

Actin, Spectrin, and Associated Proteins Form a Periodic Cytoskeletal Structure in Axons

(2012) K. Xu et al.   SCIENCE

Regulation of PCDH15 function in mechanosensory hair cells by alternative splicing of the cytoplasmic domain

(2011) S. W. Webb et al.   DEVELOPMENT

Mutations in PTPRQ Are a Cause of Autosomal-Recessive Nonsyndromic Hearing Impairment DFNB84 and Associated with Vestibular Dysfunction

(2010) Margit Schraders et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Targeted Capture and Next-Generation Sequencing Identifies C9orf75, Encoding Taperin, as the Mutated Gene in Nonsyndromic Deafness DFNB79

(2010) Atteeq Ur Rehman et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Actin-Bundling Protein TRIOBP Forms Resilient Rootlets of Hair Cell Stereocilia Essential for Hearing

(2010) Shin-ichiro Kitajiri et al.   CELL

The cell biology of hearing

(2010) Martin Schwander et al.   JOURNAL OF CELL BIOLOGY

Mechanotransduction by Hair Cells: Models, Molecules, and Mechanisms

(2009) Peter G. Gillespie et al.   CELL

Linking genes underlying deafness to hair-bundle development and function

(2009) Christine Petit et al.   NATURE NEUROSCIENCE

Harmonin Mutations Cause Mechanotransduction Defects in Cochlear Hair Cells

(2009) Nicolas Grillet et al.   NEURON