Article
Plant Sciences
Thando C. Twala, Jolene T. Fisher, Kelsey L. Glennon
Summary: The persistence of Afrotemperate taxa may be threatened under climate change. The unique ranges of podocarps in southern Africa raise questions about their future persistence. This study examines the current and future distributions of podocarps in South Africa and identifies the key climatic factors that govern their distributions.
Editorial Material
Endocrinology & Metabolism
Tatsuhito Himeno, Hideki Kamiya, Jiro Nakamura
Summary: Diabetic neuropathy, the most frequent complication of diabetes, lacks accessible objective assessments. Rethinking the concept and definition of diabetic neuropathy is essential for successful development of diagnostic and therapeutic methods.
JOURNAL OF DIABETES INVESTIGATION
(2022)
Article
Biochemistry & Molecular Biology
Shou-Hsien Li, Yang Liu, Chia-Fen Yeh, Yuchen Fu, Carol K. L. Yeung, Chun-Cheng Lee, Chi-Cheng Chiu, Tung Hui Kuo, Fang-Tse Chan, Yu-Chia Chen, Wen-Ya Ko, Cheng-Te Yao
Summary: The endangered black-faced spoonbill experienced a severe population bottleneck in the recent past, leading to decreased genetic diversity and increased accumulation of deleterious mutations. Despite a significant population recovery in recent years, the bird still exhibits higher levels of inbreeding, potentially resulting in more deleterious phenotypic effects compared to its sister species, the royal spoonbill. It is important to continuously monitor genetic erosion, inbreeding, and mutation load in endangered species to ensure their long-term survival.
Article
Political Science
Hanneke Beaulieu, Guy Chiasson, Edith Leclerc
Summary: The Staples industries dominated Quebec's forestry sector, but a new law in 2013 signaled a shift towards a post-staples economy. However, a more nuanced reading of the State's role reveals a non-linear trajectory of the forest sector in Quebec.
CANADIAN JOURNAL OF POLITICAL SCIENCE-REVUE CANADIENNE DE SCIENCE POLITIQUE
(2021)
Article
Health Care Sciences & Services
Jack Thepsourinthone, Tinashe Dune, Pranee Liamputtong, Amit Arora
Summary: The study found that Australian gay men experience social pressure and discrimination under heteronormative norms, leading to self-loathing, shame, and internalized homonegativity, resulting in feelings of isolation.
Article
Evolutionary Biology
Catherine O'Reilly, Peter Turner, Declan T. O'Mahony, Joshua P. Twining, David G. Tosh, Christopher Smal, Kate McAney, Ciara Powell, John Power, Denise B. O'Meara
Summary: The study on genetic diversity of pine martens in Ireland reveals evidence of a genetic bottleneck and low effective population size, which may result in further reductions of diversity in the future. Despite the lack of genetic structure, the Irish population shows reduced diversity compared to other carnivores in Ireland, with haplotypes shared or genetically similar to those commonly found in southern Europe.
BIOLOGICAL JOURNAL OF THE LINNEAN SOCIETY
(2021)
Article
Multidisciplinary Sciences
Charlene Adaken, Janet T. Scott, Raman Sharma, Robin Gopal, Steven Dicks, Saidia Niazi, Samreen Ijaz, Tansy Edwards, Catherine C. Smith, Christine P. Cole, Philip Kamara, Osman Kargbo, Heidi A. Doughty, Johan van Griensven, Peter W. Horby, Sahr M. Gevao, Foday Sahr, Richard J. Dimelow, Richard S. Tedder, Malcolm G. Semple, William A. Paxton, Georgios Pollakis
Summary: Neutralizing antibody function is crucial for vaccine and therapy efficacy. In this study, a wide spectrum of antibody responses in healthy survivors of the Sierra Leone EBOV outbreak was described, with pseudo-particle virus-neutralizing antibodies correlating with total anti-EBOV reactivity. A pharmacodynamic model identified a decay half-life and doubling time in survivors, suggesting that EBOV antibody reactivity declines over time after recovery. Vigilant follow-up and possible vaccine immunization for de novo antigenic stimulation should be considered to prevent EBOV viral recrudescence in recovering individuals.
Article
Pediatrics
Claudette Amuzu, Peter Bai James, Abdulai Jawo Bah, Alex Vandy Saffa Bayoh, Shepherd Roee Singer
Summary: Child survivors of the 2013-2016 West African Ebola virus disease outbreak were more likely to experience musculoskeletal, ocular, auditory, and neurological symptoms compared to their close contacts over a year after the outbreak ended. Joint pain and headache were the most common self-reported symptoms in both groups.
Review
Immunology
Betty Diamond
Summary: I have journeyed through my career as a scientific grasshopper, delving into different questions within the field of lupus. It has been incredibly fulfilling. The world of scientific exploration is endlessly captivating, and achieving success in studies that you care about alongside colleagues and trainees fosters strong and lasting connections. Science is not without its challenges, especially as a woman, but the determination to understand a disease remains unwavering.
ANNUAL REVIEW OF IMMUNOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Shuhui Wang Lorkowski, Jonathan D. Smith
Summary: High-density lipoprotein cholesterol (HDL-C) levels are inversely correlated with coronary heart disease (CHD), but the causal relationship between HDL and CHD is unclear. Recent studies have challenged the hypothesis that HDL is protective against CHD, but subsequent research suggests that specific HDL characteristics are causally related to decreased CHD. Different aspects of HDL structure and function may better indicate HDL's protective activity against CHD, beyond simply measuring HDL-C levels.
Article
Political Science
Luca Bernardi, Mikko Mattila, Achillefs Papageorgiou, Lauri Rapeli
Summary: Depression is a common health problem in the developed world, and it is negatively related to voting and political efficacy. This research has important implications for political representation.
POLITICAL PSYCHOLOGY
(2023)
Article
Multidisciplinary Sciences
M. Juga, F. Nyabadza, F. Chirove
Summary: Ebola virus disease (EVD) is highly stigmatised due to its high infectivity and case fatality rate. A mathematical model shows that both internal and external stigmatisation of Ebola survivors can increase the burden of the disease by promoting infected individuals to hide their infection and unsafe burials. Strategies to end stigmatisation and promote safe burials are crucial in averting the EVD burden.
SCIENTIFIC REPORTS
(2023)
Editorial Material
Multidisciplinary Sciences
Robert F. Garry
Summary: The Ebola virus can remain latent in human survivors for an extended period of time, as shown by a genomic comparison between the 2021 outbreak in Guinea and the West African outbreak that ended in 2016.
Article
Cell Biology
Jun Liu, John C. Trefry, April M. Babka, Christopher W. Schellhase, Kayla M. Coffin, Janice A. Williams, Jo Lynne W. Raymond, Paul R. Facemire, Taylor B. Chance, Neil M. Davis, Jennifer L. Scruggs, Franco D. Rossi, Andrew D. Haddow, Justine M. Zelko, Sandra L. Bixler, Ian Crozier, Patrick L. Iversen, Margaret L. Pitt, Jens H. Kuhn, Gustavo Palacios, Xiankun Zeng
Summary: Persistent Ebola virus infection in the brain ventricular system can occur in macaque survivors after therapeutic treatment, leading to severe tissue damage and inflammation.
SCIENCE TRANSLATIONAL MEDICINE
(2022)
Article
Immunology
Jonathan Dyal, Aaron Kofman, Jomah Z. Kollie, John Fankhauser, Romeo Orone, Moses J. Soka, Uriah Glaybo, Armah Kiawu, Edna Freeman, Giovanni Giah, Henry D. Tony, Mylene Faikai, Mary Jawara, Kuku Kamara, Samuel Kamara, Benjamin Flowers, Mohammed L. Kromah, Rodel Desamu-Thorpe, James Graziano, Shelley Brown, Maria E. Morales-Betoulle, Deborah L. Cannon, Kaihong Su, Susanne L. Linderman, Mateusz Plucinski, Eric Rogier, Richard S. Bradbury, W. Evan Secor, Katherine E. Bowden, Christi Phillips, Mary N. Carrington, Yeon-Hwa Park, Maureen P. Martin, Maria Del Pilar Aguinaga, Robert Mushi, Dana L. Haberling, Elizabeth D. Ervin, John D. Klena, Moses Massaquoi, Tolbert Nyenswah, Stuart T. Nichol, David E. Chiriboga, Desmond E. Williams, Steven H. Hinrichs, Rafi Ahmed, Benjamin T. Vonhm, Pierre E. Rollin, Lawrence J. Purpura, Mary J. Choi
Summary: This study aimed to investigate the risk factors for prolonged Ebola virus persistence in the semen of male Ebola virus disease (EVD) survivors. The results showed that older age, decreased illness severity, intraocular lens opacifications, elevated total serum immunoglobulin G3 levels, and expression of the HLA-C*03:04 allele may be associated with the persistence of Ebola virus in semen.
CLINICAL INFECTIOUS DISEASES
(2023)
