NLRP3 Activation Was Regulated by DNA Methylation Modification duringMycobacterium tuberculosisInfection

Dopamine Controls Systemic Inflammation through Inhibition of NLRP3 Inflammasome

(2015) Yiqing Yan et al.   CELL

β-arrestin1 Is Critical for the Full Activation of NLRP3 and NLRC4 Inflammasomes

(2015) Kairui Mao et al.   JOURNAL OF IMMUNOLOGY

Reversing DNA Methylation: Mechanisms, Genomics, and Biological Functions

(2014) Hao Wu et al.   CELL

Aberrant Toll-like receptor 2 promoter methylation in blood cells from patients with pulmonary tuberculosis

(2014) Yung-Che Chen et al.   JOURNAL OF INFECTION

Polymorphisms in the Interleukin 18 Receptor 1 Gene and Tuberculosis Susceptibility among Chinese

(2014) Junxian Zhang et al.   PLoS One

Dynamic Readers for 5-(Hydroxy)Methylcytosine and Its Oxidized Derivatives

(2013) Cornelia G. Spruijt et al.   CELL

Omega-3 Fatty Acids Prevent Inflammation and Metabolic Disorder through Inhibition of NLRP3 Inflammasome Activation

(2013) Yiqing Yan et al.   IMMUNITY

LRRFIP2 negatively regulates NLRP3 inflammasome activation in macrophages by promoting Flightless-I-mediated caspase-1 inhibition

(2013) Jing Jin et al.   Nature Communications

DNA methylation presents distinct binding sites for human transcription factors

(2013) Shaohui Hu et al.   eLife

Mycobacterium tuberculosis and the host cell inflammasome: a complex relationship

(2013) Volker Briken et al.   Frontiers in Cellular and Infection Microbiology

Mycobacterium Tuberculosis Activates the DNA-Dependent Cytosolic Surveillance Pathway within Macrophages

(2012) Paolo S. Manzanillo et al.   Cell Host & Microbe

Cutting Edge: Nitric Oxide Inhibits the NLRP3 Inflammasome

(2012) E. Hernandez-Cuellar et al.   JOURNAL OF IMMUNOLOGY

Inflammasomes in health and disease

(2012) Till Strowig et al.   NATURE

NLRP3 is activated in Alzheimer’s disease and contributes to pathology in APP/PS1 mice

(2012) Michael T. Heneka et al.   NATURE

Nitric oxide controls the immunopathology of tuberculosis by inhibiting NLRP3 inflammasome–dependent processing of IL-1β

(2012) Bibhuti B Mishra et al.   NATURE IMMUNOLOGY

Just say NO to NLRP3

(2012) Manira Rayamajhi et al.   NATURE IMMUNOLOGY

The Inflammasome NLRs in Immunity, Inflammation, and Associated Diseases

(2011) Beckley K. Davis et al.   Annual Review of Immunology

Activation of the NLRP3 inflammasome byMycobacterium tuberculosisis uncoupled from susceptibility to active tuberculosis

(2011) Anca Dorhoi et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Interleukin-6 expression was regulated by epigenetic mechanisms in response to influenza virus infection or dsRNA treatment

(2011) Bikui Tang et al.   MOLECULAR IMMUNOLOGY

Human Macrophages Infected with a High Burden of ESAT-6-Expressing M. tuberculosis Undergo Caspase-1- and Cathepsin B-Independent Necrosis

(2011) Amanda Welin et al.   PLoS One

Epstein-Barr virus-specific methylation of human genes in gastric cancer cells

(2011) Julie L Ryan et al.   Infectious Agents and Cancer

The Inflammasomes

(2010) Kate Schroder et al.   CELL

Nucleosome-Interacting Proteins Regulated by DNA and Histone Methylation

(2010) Till Bartke et al.   CELL

Mycobacterium tuberculosis protein ESAT-6 is a potent activator of the NLRP3/ASC inflammasome

(2010) Bibhuti B. Mishra et al.   CELLULAR MICROBIOLOGY

Vitamin D receptor gene methylation is associated with ethnicity, tuberculosis, and TaqI polymorphism

(2010) Charlene Andraos et al.   HUMAN IMMUNOLOGY

IL-32: A Host Proinflammatory Factor against Influenza Viral Replication Is Upregulated by Aberrant Epigenetic Modifications during Influenza A Virus Infection

(2010) W. Li et al.   JOURNAL OF IMMUNOLOGY

Host-Detrimental Role of Esx-1-Mediated Inflammasome Activation in Mycobacterial Infection

(2010) Fredric Carlsson et al.   PLoS Pathogens