Mouse Models in Prostate Cancer Translational Research: From Xenograft to PDX

Association between Seminal Vesicle Invasion and Prostate Cancer Detection Location after Transrectal Systemic Biopsy among Men Who Underwent Radical Prostatectomy

(2016) Young Ik Lee et al.   PLoS One

Treatment of mCRPC in the AR-axis-targeted therapy-resistant state

(2015) K. Chi et al.   ANNALS OF ONCOLOGY

Tumor-Derived Cell Lines as Molecular Models of Cancer Pharmacogenomics

(2015) A. Goodspeed et al.   MOLECULAR CANCER RESEARCH

Addition of PSMA ADC to enzalutamide therapy significantly improves survival in in vivo model of castration resistant prostate cancer

(2015) Vincent A. DiPippo et al.   PROSTATE

Next generation patient-derived prostate cancer xenograft models

(2014) Yuzhuo Wang et al.   ASIAN JOURNAL OF ANDROLOGY

Cancer statistics, 2014

(2014) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Hydrogel-Based 3D Model of Patient-Derived Prostate Xenograft Tumors Suitable for Drug Screening

(2014) Eliza L. S. Fong et al.   MOLECULAR PHARMACEUTICS

Evolution of androgen receptor targeted therapy for advanced prostate cancer

(2014) Yien Ning Sophia Wong et al.   Nature Reviews Clinical Oncology

Enzalutamide in Metastatic Prostate Cancer before Chemotherapy

(2014) Tomasz M. Beer et al.   NEW ENGLAND JOURNAL OF MEDICINE

Humanized NOD-SCID IL2rg –/– mice as a preclinical model for cancer research and its potential use for individualized cancer therapies

(2013) Qianjun Zhou et al.   CANCER LETTERS

High Fidelity Patient-Derived Xenografts for Accelerating Prostate Cancer Discovery and Drug Development

(2013) D. Lin et al.   CANCER RESEARCH

Patient-Derived Tumor Xenografts: Transforming Clinical Samples into Mouse Models

(2013) D. Siolas et al.   CANCER RESEARCH

Humanized mice for the study of infectious diseases

(2013) Michael A Brehm et al.   CURRENT OPINION IN IMMUNOLOGY

Humanized mice: novel model for studying mechanisms of human immune-based therapies

(2013) Louis Gonzalez et al.   IMMUNOLOGIC RESEARCH

Evaluating cell lines as tumour models by comparison of genomic profiles

(2013) Silvia Domcke et al.   Nature Communications

Recreating the tumor microenvironment in a bilayer, hyaluronic acid hydrogel construct for the growth of prostate cancer spheroids

(2012) Xian Xu et al.   BIOMATERIALS

Patient-derived tumour xenografts as models for oncology drug development

(2012) John J. Tentler et al.   Nature Reviews Clinical Oncology

Global gene expression profiling confirms the molecular fidelity of primary tumor-based orthotopic xenograft mouse models of medulloblastoma

(2012) Xiumei Zhao et al.   NEURO-ONCOLOGY

Tumor grafts derived from women with breast cancer authentically reflect tumor pathology, growth, metastasis and disease outcomes

(2011) Yoko S DeRose et al.   NATURE MEDICINE

Abiraterone and Increased Survival in Metastatic Prostate Cancer

(2011) Johann S. de Bono et al.   NEW ENGLAND JOURNAL OF MEDICINE

Retaining cell-cell contact enables preparation and culture of spheroids composed of pure primary cancer cells from colorectal cancer

(2011) J. Kondo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The complexities of identifying a cell of origin for human prostate cancer

(2010) Gail P Risbridger et al.   ASIAN JOURNAL OF ANDROLOGY

Patient-Derived First Generation Xenografts of Non-Small Cell Lung Cancers: Promising Tools for Predicting Drug Responses for Personalized Chemotherapy

(2010) X. Dong et al.   CLINICAL CANCER RESEARCH

Local regulation of human breast xenograft models

(2010) Jodie M. Fleming et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Prostate cancer from basal cells

(2010) Rebecca Kirk   Nature Reviews Clinical Oncology

Loss of Androgen Receptor-Dependent Growth Suppression by Prostate Cancer Cells Can Occur Independently from Acquiring Oncogenic Addiction to Androgen Receptor Signaling

(2010) Jason M. D'Antonio et al.   PLoS One

Development of metastatic and non-metastatic tumor lines from a patient's prostate cancer specimen-identification of a small subpopulation with metastatic potential in the primary tumor

(2010) Dong Lin et al.   PROSTATE

Engineering Tumors: A Tissue Engineering Perspective in Cancer Biology

(2010) Emily Burdett et al.   TISSUE ENGINEERING PART B-REVIEWS

Experimental orthotopic prostate tumor in nude mice: Techniques for local cell inoculation and three-dimensional ultrasound monitoring

(2010) Matthias Saar et al.   UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS

Brca2 and Trp53 Deficiency Cooperate in the Progression of Mouse Prostate Tumourigenesis

(2010) Jeffrey C. Francis et al.   PLoS Genetics

Lung cancer xenografting alters microRNA profile but not immunophenotype

(2009) Paul N. Bogner et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Hyaluronic acid-based hydrogels as 3D matrices for in vitro evaluation of chemotherapeutic drugs using poorly adherent prostate cancer cells

(2009) Lisa A. Gurski et al.   BIOMATERIALS

A Primary Xenograft Model of Small-Cell Lung Cancer Reveals Irreversible Changes in Gene Expression Imposed by Culture In vitro

(2009) V. C. Daniel et al.   CANCER RESEARCH

Simultaneous haploinsufficiency of Pten and Trp53 tumor suppressor genes accelerates tumorigenesis in a mouse model of prostate cancer

(2009) Suzana S. Couto et al.   DIFFERENTIATION

Molecular profiling and characterization of luminal-like and basal-like in vivo breast cancer xenograft models

(2009) Anna Bergamaschi et al.   Molecular Oncology

A luminal epithelial stem cell that is a cell of origin for prostate cancer

(2009) Xi Wang et al.   NATURE

Cancer Statistics, 2008

(2008) A. Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Osteotropic cancers: From primary tumor to bone

(2008) Jeroen T. Buijs et al.   CANCER LETTERS

Conditional Deletion of Insulin-like Growth Factor-I Receptor in Prostate Epithelium

(2008) B. W. Sutherland et al.   CANCER RESEARCH

Prostate Cancer Induces Bone Metastasis through Wnt-Induced Bone Morphogenetic Protein-Dependent and Independent Mechanisms

(2008) J. Dai et al.   CANCER RESEARCH

The current state of preclinical prostate cancer animal models

(2008) Kenneth J. Pienta et al.   PROSTATE

Role of the TMPRSS2-ERG Gene Fusion in Prostate Cancer

(2008) Scott A. Tomlins et al.   NEOPLASIA