Grignard Reactions in Cyclopentyl Methyl Ether

Enantioselective Syntheses of Heteroyohimbine Natural Products: A Unified Approach through Cooperative Catalysis

(2015) Ashkaan Younai et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Transition-Metal-Free α-Arylation of Enolizable Aryl Ketones and Mechanistic Evidence for a Radical Process

(2015) Martin Pichette Drapeau et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Robust, Eco-Friendly Access to Secondary Thioamides through the Addition of Organolithium Reagents to Isothiocyanates in Cyclopentyl Methyl Ether (CPME)

(2015) Vittorio Pace et al.   CHEMISTRY-A EUROPEAN JOURNAL

Comparative performance evaluation and systematic screening of solvents in a range of Grignard reactions

(2013) Asha Kadam et al.   GREEN CHEMISTRY

Sanofi’s Solvent Selection Guide: A Step Toward More Sustainable Processes

(2013) Denis Prat et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Continuous Flow-Processing of Organometallic Reagents Using an Advanced Peristaltic Pumping System and the Telescoped Flow Synthesis of (E/Z)-Tamoxifen

(2013) Philip R. D. Murray et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Evaluation of cyclopentyl methyl ether (CPME) as a solvent for radical reactions

(2013) Shoji Kobayashi et al.   TETRAHEDRON

2-Methyltetrahydrofuran: A Versatile Eco-Friendly Alternative to THF in Organometallic Chemistry

(2012) Vittorio Pace   AUSTRALIAN JOURNAL OF CHEMISTRY

2-Methyltetrahydrofuran (2-MeTHF): A Biomass-Derived Solvent with Broad Application in Organic Chemistry

(2012) Vittorio Pace et al.   ChemSusChem

Tamoxifen: A Synthetic Overview

(2012) Konstantinos M. Kasiotis et al.   CURRENT ORGANIC CHEMISTRY

Catalytic Enantioselective Protonation of Nitronates Utilizing an Organocatalyst Chiral Only at Sulfur

(2012) Kyle L. Kimmel et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ring-Expansion Reaction of Oximes with Aluminum Reductants

(2012) Hidetsura Cho et al.   MOLECULES

Manufacture of a β-Hydroxyester via a Continuous Reformatsky Process

(2012) Gabriel Loh et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

A Catalytic Asymmetric Borono Variant of Hosomi-Sakurai Reactions with N,O-Aminals

(2011) Yi-Yong Huang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The importance of Green Chemistry in Process Research and Development

(2011) Peter J. Dunn   CHEMICAL SOCIETY REVIEWS

Chemical Synthesis of Helicobacter pylori Lipopolysaccharide Partial Structures and their Selective Proinflammatory Responses

(2011) Atsushi Shimoyama et al.   CHEMISTRY-A EUROPEAN JOURNAL

Cyclopentyl Methyl Ether: An Alternative Solvent for Palladium-Catalyzed Direct Arylation of Heteroaromatics

(2011) Kassem Beydoun et al.   ChemSusChem

Eco-friendly synthesis of β-nitro ketones from conjugated enones: an important improvement of the Miyakoshi procedure

(2011) Serena Gabrielli et al.   GREEN CHEMISTRY

Expanding GSK's solvent selection guide – embedding sustainability into solvent selection starting at medicinal chemistry

(2011) Richard K. Henderson et al.   GREEN CHEMISTRY

Searching for green solvents

(2011) Philip G. Jessop   GREEN CHEMISTRY

Asymmetric Catalytic Cycloetherification Mediated by Bifunctional Organocatalysts

(2011) Keisuke Asano et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Generation and exploitation of acyclic azomethine imines in chiral Brønsted acid catalysis

(2011) Takuya Hashimoto et al.   Nature Chemistry

C−O Hydrogenolysis Catalyzed by Pd-PMHS Nanoparticles in the Company of Chloroarenes

(2011) Ronald J. Rahaim et al.   ORGANIC LETTERS

Toxicological Assessment of 2-Methyltetrahydrofuran and Cyclopentyl Methyl Ether in Support of Their Use in Pharmaceutical Chemical Process Development

(2011) Vincent Antonucci et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Continuous Preparation of Arylmagnesium Reagents in Flow with Inline IR Monitoring

(2011) Tobias Brodmann et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Rearrangement of 4,5α-epoxymorphinan derivatives with carbamoylepoxy rings provide novel oxazatricyclodecane structures

(2011) Kohei Hayashida et al.   TETRAHEDRON

Enantio- and diastereoselective addition of cyclohexylMeldrum's acid to β- and α,β-disubstituted nitroalkenesvia N-sulfinyl urea catalysis

(2011) Kyle L. Kimmel et al.   Chemical Science

Cobalt-Catalyzed Addition Reaction of Organoboronic Acids with Aldehydes: Highly Enantioselective Synthesis of Diarylmethanols

(2010) Jaganathan Karthikeyan et al.   CHEMISTRY-A EUROPEAN JOURNAL

The Synthesis of Highly Coplanar Oligothiophenes Induced by Bulky Rind Groups

(2010) Takashi Otani et al.   Chemistry-An Asian Journal

Zinc(II)-Catalyzed Addition of Grignard Reagents to Ketones

(2010) Manabu Hatano et al.   JOURNAL OF ORGANIC CHEMISTRY

Reaction of Grignard reagents with carbonyl compounds under continuous flow conditions

(2010) E. Riva et al.   TETRAHEDRON

Green Chemistry: Principles and Practice

(2009) Paul Anastas et al.   CHEMICAL SOCIETY REVIEWS

A Scalable Zinc Activation Procedure Using DIBAL-H in a Reformatsky Reaction

(2009) Michael J. Girgis et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Improved Pinner Reaction with CPME as a Solvent

(2009) Kiyoshi Watanabe et al.   SYNTHETIC COMMUNICATIONS

Ni(COD)2/4-ClC6H4COR-catalyzed addition reactions of arylboroxines with aldehydes

(2009) Chun-Hui Xing et al.   TETRAHEDRON LETTERS

Solvents in organic synthesis: Replacement and multi-step reaction systems

(2008) Rafiqul Gani et al.   COMPUTERS & CHEMICAL ENGINEERING

Palladium-Catalyzed 1,2-Addition of Potassium Aryl- and Alkenyltrifluoroborates to Aldehydes using Thioether−Imidazolinium Carbene Ligands

(2008) Masami Kuriyama et al.   JOURNAL OF ORGANIC CHEMISTRY

A Scalable Synthesis of an Azabicyclooctanyl Derivative, a Novel DPP-4 Inhibitor

(2008) Zhongbo Fei et al.   JOURNAL OF ORGANIC CHEMISTRY

Cascade Reactions Using LiAlH4 and Grignard Reagents in the Presence of Water

(2007) M. Brett Runge et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION