Immune activation and neuroinflammation in alcohol use and HIV infection: evidence for shared mechanisms

Subtypes of depressive symptoms and inflammatory biomarkers: An exploratory study on a sample of HIV-positive patients

(2016) A. Norcini Pala et al.   BRAIN BEHAVIOR AND IMMUNITY

Do Biomarkers of Inflammation, Monocyte Activation, and Altered Coagulation Explain Excess Mortality Between HIV Infected and Uninfected People?

(2016) Kaku A. So-Armah et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Identifying Symptom Patterns in People Living With HIV Disease

(2016) Natalie L. Wilson et al.   JANAC-JOURNAL OF THE ASSOCIATION OF NURSES IN AIDS CARE

Glutamine supplementation attenuates ethanol-induced disruption of apical junctional complexes in colonic epithelium and ameliorates gut barrier dysfunction and fatty liver in mice

(2016) Kamaljit K. Chaudhry et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Opposing effects of alcohol on the immune system

(2016) Tasha Barr et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Immune activation in HIV infection

(2016) Mickaël J. Ploquin et al.   Current Opinion in HIV and AIDS

Microbial translocation and microbiome dysbiosis in HIV-associated immune activation

(2016) Alexander S. Zevin et al.   Current Opinion in HIV and AIDS

Loss of Function of Intestinal IL-17 and IL-22 Producing Cells Contributes to Inflammation and Viral Persistence in SIV-Infected Rhesus Macaques

(2016) Emily S. Ryan et al.   PLoS Pathogens

Could antiretroviral neurotoxicity play a role in the pathogenesis of cognitive impairment in treated HIV disease?

(2015) Jonathan Underwood et al.   AIDS

Association of microbial translocation biomarkers with clinical outcome in controllers HIV-infected patients

(2015) Agathe León et al.   AIDS

Acute immunomodulatory effects of binge alcohol ingestion

(2015) Majid Afshar et al.   ALCOHOL

The effect of acute alcohol intoxication on gut wall integrity in healthy male volunteers; a randomized controlled trial

(2015) W.J. de Jong et al.   ALCOHOL

Unhealthy Alcohol Use is Associated with Monocyte Activation Prior to Starting Antiretroviral Therapy

(2015) Adam W. Carrico et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Histone Deacetylase Gene Expression Following Binge Alcohol Consumption in Rats and Humans

(2015) Jose Antonio López-Moreno et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

HIV infection induces structural and functional changes in high density lipoproteins

(2015) Marc O. Siegel et al.   ATHEROSCLEROSIS

Quantitative Magnetization Transfer Imaging as a Biomarker for Effects of Systemic Inflammation on the Brain

(2015) Neil A. Harrison et al.   BIOLOGICAL PSYCHIATRY

Role of the immune system in HIV-associated neuroinflammation and neurocognitive implications

(2015) Suzi Hong et al.   BRAIN BEHAVIOR AND IMMUNITY

The HIV-1 transgenic rat model of neuroHIV

(2015) Michael Vigorito et al.   BRAIN BEHAVIOR AND IMMUNITY

Targeting the Toll of Drug Abuse: The Translational Potential of Toll-Like Receptor 4

(2015) Ryan Bachtell et al.   CNS & Neurological Disorders-Drug Targets

HIV encephalopathy: glial activation and hippocampal neuronal apoptosis, but limited neural repair

(2015) SC Tauber et al.   HIV MEDICINE

Elevated Soluble CD14 and Lower D-Dimer Are Associated With Cigarette Smoking and Heavy Episodic Alcohol Use in Persons Living With HIV

(2015) Patricia A. Cioe et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Plasma and Cerebrospinal Fluid Biomarkers Predict Cerebral Injury in HIV-Infected Individuals on Stable Combination Antiretroviral Therapy

(2015) Albert M. Anderson et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Effect of Probiotics (Saccharomyces boulardii) on Microbial Translocation and Inflammation in HIV-Treated Patients

(2015) Judit Villar-García et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Sterile alpha motif and histidine/aspartic acid domain-containing protein 1 (SAMHD1)-facilitated HIV restriction in astrocytes is regulated by miRNA-181a

(2015) Sudheesh Pilakka-Kanthikeel et al.   Journal of Neuroinflammation

CSF biomarkers of monocyte activation and chemotaxis correlate with magnetic resonance spectroscopy metabolites during chronic HIV disease

(2015) Albert M. Anderson et al.   JOURNAL OF NEUROVIROLOGY

Sex Differences in Depressive and Socioemotional Responses to an Inflammatory Challenge: Implications for Sex Differences in Depression

(2015) Mona Moieni et al.   NEUROPSYCHOPHARMACOLOGY

CRF-Amplified Neuronal TLR4/MCP-1 Signaling Regulates Alcohol Self-Administration

(2015) Harry L June et al.   NEUROPSYCHOPHARMACOLOGY

Molecular mechanisms of synaptic remodeling in alcoholism

(2015) Evan J. Kyzar et al.   NEUROSCIENCE LETTERS

Increased Sensitivity to Binge Alcohol-Induced Gut Leakiness and Inflammatory Liver Disease in HIV Transgenic Rats

(2015) Atrayee Banerjee et al.   PLoS One

Experimental colitis in SIV-uninfected rhesus macaques recapitulates important features of pathogenic SIV infection

(2015) Xing Pei Hao et al.   Nature Communications

Alcohol and Cannabinoids Differentially Affect HIV Infection and Function of Human Monocyte-Derived Dendritic Cells (MDDC)

(2015) Marisela Agudelo et al.   Frontiers in Microbiology

HIV-1 gp120 and morphine induced oxidative stress: role in cell cycle regulation

(2015) Thangavel Samikkannu et al.   Frontiers in Microbiology

Associations of Cocaine Use and HIV Infection With the Intestinal Microbiota, Microbial Translocation, and Inflammation

(2015) Gretchen E Volpe et al.   Journal of Studies on Alcohol and Drugs

Predictors of virologic response in persons who start antiretroviral therapy during recent HIV infection

(2014) Maile Y. Karris et al.   AIDS

Microglia Development and Function

(2014) Debasis Nayak et al.   Annual Review of Immunology

Brain Inflammation is a Common Feature of HIV-Infected Patients without HIV Encephalitis or Productive Brain Infection

(2014) Eleonora Tavazzi et al.   CURRENT HIV RESEARCH

Structural brain differences in alcohol-dependent individuals with and without comorbid substance dependence

(2014) Anderson Mon et al.   DRUG AND ALCOHOL DEPENDENCE

HIV infection and cardiovascular disease

(2014) L. G. Hemkens et al.   EUROPEAN HEART JOURNAL

The glia/neuron ratio: How it varies uniformly across brain structures and species and what that means for brain physiology and evolution

(2014) Suzana Herculano-Houzel   GLIA

Lactobacillus casei MYL01 modulates the proinflammatory state induced by ethanol in an in vitro model

(2014) Yi-Heng Chiu et al.   JOURNAL OF DAIRY SCIENCE

Moderate Alcohol Induces Stress Proteins HSF1 and hsp70 and Inhibits Proinflammatory Cytokines Resulting in Endotoxin Tolerance

(2014) Sujatha Muralidharan et al.   JOURNAL OF IMMUNOLOGY

Gut Epithelial Barrier Dysfunction and Innate Immune Activation Predict Mortality in Treated HIV Infection

(2014) Peter W. Hunt et al.   JOURNAL OF INFECTIOUS DISEASES

Intestinal Microbiota, Microbial Translocation, and Systemic Inflammation in Chronic HIV Infection

(2014) Duy M. Dinh et al.   JOURNAL OF INFECTIOUS DISEASES

Altered metabolism of gut microbiota contributes to chronic immune activation in HIV-infected individuals

(2014) J F Vázquez-Castellanos et al.   Mucosal Immunology

Acute Binge Drinking Increases Serum Endotoxin and Bacterial DNA Levels in Healthy Individuals

(2014) Shashi Bala et al.   PLoS One

Intestinal permeability, gut-bacterial dysbiosis, and behavioral markers of alcohol-dependence severity

(2014) Sophie Leclercq et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Histone deacetylases in memory and cognition

(2014) J. Penney et al.   Science Signaling

Neuroimaging of HIV-associated neurocognitive disorders (HAND)

(2014) Beau M. Ances et al.   Current Opinion in HIV and AIDS

Vorinostat positively regulates synaptic plasticity genes expression and spine density in HIV infected neurons: role of nicotine in progression of HIV-associated neurocognitive disorder

(2014) Venkata Subba Atluri et al.   Molecular Brain

A Compositional Look at the Human Gastrointestinal Microbiome and Immune Activation Parameters in HIV Infected Subjects

(2014) Ece A. Mutlu et al.   PLoS Pathogens

Acute and chronic effects of ethanol on learning-related synaptic plasticity

(2013) Charles F. Zorumski et al.   ALCOHOL

Chronic Ethanol Consumption Modulates Growth Factor Release, Mucosal Cytokine Production, and MicroRNA Expression in Nonhuman Primates

(2013) Mark Asquith et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Impaired Lipoprotein Processing in HIV Patients on Antiretroviral Therapy

(2013) Baiba K. Gillard et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Microbial Translocation in the Pathogenesis of HIV Infection and AIDS

(2013) Giulia Marchetti et al.   CLINICAL MICROBIOLOGY REVIEWS

Ethanol induces TLR4/TLR2 association, triggering an inflammatory response in microglial cells

(2013) Sara Fernandez-Lizarbe et al.   JOURNAL OF NEUROCHEMISTRY

A Concise Panel of Biomarkers Identifies Neurocognitive Functioning Changes in HIV-Infected Individuals

(2013) Thomas D. Marcotte et al.   Journal of Neuroimmune Pharmacology

Relationship of plasma cytokines and clinical biomarkers to memory performance in HIV

(2013) Stephen Correia et al.   JOURNAL OF NEUROIMMUNOLOGY

Progressive cerebral injury in the setting of chronic HIV infection and antiretroviral therapy

(2013) Assawin Gongvatana et al.   JOURNAL OF NEUROVIROLOGY

Human Synaptic Plasticity Gene Expression Profile and Dendritic Spine Density Changes in HIV-Infected Human CNS Cells: Role in HIV-Associated Neurocognitive Disorders (HAND)

(2013) Venkata Subba Rao Atluri et al.   PLoS One

Mechanisms of HIV Entry into the CNS: Increased Sensitivity of HIV Infected CD14+CD16+ Monocytes to CCL2 and Key Roles of CCR2, JAM-A, and ALCAM in Diapedesis

(2013) Dionna W. Williams et al.   PLoS One

Dysbiosis of the Gut Microbiota Is Associated with HIV Disease Progression and Tryptophan Catabolism

(2013) Ivan Vujkovic-Cvijin et al.   Science Translational Medicine

Widespread and sustained cognitive deficits in alcoholism: a meta-analysis

(2012) Katherine Stavro et al.   ADDICTION BIOLOGY

Microbial Translocation Across the GI Tract

(2012) Jason M. Brenchley et al.   Annual Review of Immunology

Dopaminergic Mechanisms of Reduced Basal Ganglia Responses to Hedonic Reward During Interferon Alfa Administration

(2012) Lucile Capuron et al.   ARCHIVES OF GENERAL PSYCHIATRY

Regional Brain Structural Dysmorphology in Human Immunodeficiency Virus Infection: Effects of Acquired Immune Deficiency Syndrome, Alcoholism, and Age

(2012) Adolf Pfefferbaum et al.   BIOLOGICAL PSYCHIATRY

High Mobility Group Box 1/Toll-like Receptor Danger Signaling Increases Brain Neuroimmune Activation in Alcohol Dependence

(2012) Fulton T. Crews et al.   BIOLOGICAL PSYCHIATRY

Role of intestinal permeability and inflammation in the biological and behavioral control of alcohol-dependent subjects

(2012) Sophie Leclercq et al.   BRAIN BEHAVIOR AND IMMUNITY

Does an Index Composed of Clinical Data Reflect Effects of Inflammation, Coagulation, and Monocyte Activation on Mortality Among Those Aging With HIV?

(2012) A. C. Justice et al.   CLINICAL INFECTIOUS DISEASES

Life expectancy living with HIV

(2012) Fumiyo Nakagawa et al.   CURRENT OPINION IN INFECTIOUS DISEASES

Cytokine effects on the basal ganglia and dopamine function: The subcortical source of inflammatory malaise

(2012) Jennifer C. Felger et al.   FRONTIERS IN NEUROENDOCRINOLOGY

Toll-like receptor 4 participates in the myelin disruptions associated with chronic alcohol abuse

(2012) Silvia Alfonso-Loeches et al.   GLIA

Monocyte Activation Markers in Cerebrospinal Fluid Associated With Impaired Neurocognitive Testing in Advanced HIV Infection

(2012) Anupa Kamat et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Intentional Non-Adherence to Medications among HIV Positive Alcohol Drinkers: Prospective Study of Interactive Toxicity Beliefs

(2012) Seth C. Kalichman et al.   JOURNAL OF GENERAL INTERNAL MEDICINE

NADPH oxidase and reactive oxygen species contribute to alcohol-induced microglial activation and neurodegeneration

(2012) Liya Qin et al.   Journal of Neuroinflammation

Opioid Activation of Toll-Like Receptor 4 Contributes to Drug Reinforcement

(2012) M. R. Hutchinson et al.   JOURNAL OF NEUROSCIENCE

Structural brain alterations can be detected early in HIV infection

(2012) A. B. Ragin et al.   NEUROLOGY

Synbiotic therapy decreases microbial translocation and inflammation and improves immunological status in HIV-infected patients: a double-blind randomized controlled pilot trial

(2012) Luz A González-Hernández et al.   Nutrition Journal

Microbial translocation, immune activation, and HIV disease

(2012) Nichole R. Klatt et al.   TRENDS IN MICROBIOLOGY

A peripheral monocyte interferon phenotype in HIV infection correlates with a decrease in magnetic resonance spectroscopy metabolite concentrations

(2011) Lynn Pulliam et al.   AIDS

Persistence of HIV-associated cognitive impairment, inflammation, and neuronal injury in era of highly active antiretroviral treatment

(2011) Jarek Harezlak et al.   AIDS

Lipopolysaccharide affects exploratory behaviors toward novel objects by impairing cognition and/or motivation in mice: Possible role of activation of the central amygdala

(2011) Ryota Haba et al.   BEHAVIOURAL BRAIN RESEARCH

Impact of TLR4 on behavioral and cognitive dysfunctions associated with alcohol-induced neuroinflammatory damage

(2011) María Pascual et al.   BRAIN BEHAVIOR AND IMMUNITY

The inflammatory footprints of alcohol-induced oxidative damage in neurovascular components

(2011) Saleena Alikunju et al.   BRAIN BEHAVIOR AND IMMUNITY

Activation of inflammatory signaling by lipopolysaccharide produces a prolonged increase of voluntary alcohol intake in mice

(2011) Y.A. Blednov et al.   BRAIN BEHAVIOR AND IMMUNITY

HIV-1 infection and alcohol abuse: Neurocognitive impairment, mechanisms of neurodegeneration and therapeutic interventions

(2011) Yuri Persidsky et al.   BRAIN BEHAVIOR AND IMMUNITY

Induction of innate immune genes in brain create the neurobiology of addiction

(2011) F.T. Crews et al.   BRAIN BEHAVIOR AND IMMUNITY

Role of TLR4 in ethanol effects on innate and adaptive immune responses in peritoneal macrophages

(2011) María Pascual et al.   IMMUNOLOGY AND CELL BIOLOGY

Plasma sCD14 Is a Biomarker Associated With Impaired Neurocognitive Test Performance in Attention and Learning Domains in HIV Infection

(2011) Jennifer L Lyons et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Plasma Levels of Soluble CD14 Independently Predict Mortality in HIV Infection

(2011) Netanya G. Sandler et al.   JOURNAL OF INFECTIOUS DISEASES

Chemokines in cerebrospinal fluid correlate with cerebral metabolite patterns in HIV-infected individuals

(2011) Scott L. Letendre et al.   JOURNAL OF NEUROVIROLOGY

Alcohol Consumption Among HIV-Infected Women: Impact on Time to Antiretroviral Therapy and Survival

(2011) Robyn C. Neblett et al.   JOURNAL OF WOMENS HEALTH

Specific prebiotics modulate gut microbiota and immune activation in HAART-naive HIV-infected adults: results of the “COPA” pilot randomized trial

(2011) A Gori et al.   Mucosal Immunology

HIV-1 Tat upregulates expression of histone deacetylase-2 (HDAC2) in human neurons: Implication for HIV-associated neurocognitive disorder (HAND)

(2011) Zainulabedin M. Saiyed et al.   NEUROCHEMISTRY INTERNATIONAL

Induction of Innate Immune Gene Expression Cascades in Brain Slice Cultures by Ethanol: Key Role of NF-κB and Proinflammatory Cytokines

(2010) Jian Zou et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Inflammation-Induced Anhedonia: Endotoxin Reduces Ventral Striatum Responses to Reward

(2010) Naomi I. Eisenberger et al.   BIOLOGICAL PSYCHIATRY

Inflammation and social experience: An inflammatory challenge induces feelings of social disconnection in addition to depressed mood

(2010) Naomi I. Eisenberger et al.   BRAIN BEHAVIOR AND IMMUNITY

Plasma cytokine concentrations associated with HIV/hepatitis C coinfection are related to attention, executive and psychomotor functioning

(2010) Ronald A. Cohen et al.   JOURNAL OF NEUROIMMUNOLOGY

Pivotal Role of TLR4 Receptors in Alcohol-Induced Neuroinflammation and Brain Damage

(2010) S. Alfonso-Loeches et al.   JOURNAL OF NEUROSCIENCE

Peripheral biomarkers do not correlate with cognitive impairment in highly active antiretroviral therapy–treated subjects with human immunodeficiency virus type 1 infection

(2010) Bing Sun et al.   JOURNAL OF NEUROVIROLOGY

HIV-associated neurocognitive disorders before and during the era of combination antiretroviral therapy: differences in rates, nature, and predictors

(2010) Robert K. Heaton et al.   JOURNAL OF NEUROVIROLOGY

HIV-associated neurocognitive disorders persist in the era of potent antiretroviral therapy: CHARTER Study

(2010) R. K. Heaton et al.   NEUROLOGY

Biomarkers of neurological status in HIV infection: A 3-year study

(2010) Ann B. Ragin et al.   Proteomics Clinical Applications

Inhibitory effects of alcohol on glucose transport across the blood–brain barrier leads to neurodegeneration: preventive role of acetyl-l-carnitine

(2010) P. M. Abdul Muneer et al.   PSYCHOPHARMACOLOGY

Damaged Intestinal Epithelial Integrity Linked to Microbial Translocation in Pathogenic Simian Immunodeficiency Virus Infections

(2010) Jacob D. Estes et al.   PLoS Pathogens

Exposure to HIV-1 Directly Impairs Mucosal Epithelial Barrier Integrity Allowing Microbial Translocation

(2010) Aisha Nazli et al.   PLoS Pathogens

Alcohol and HIV Disease Progression: Weighing the Evidence

(2010) Judith A. Hahn et al.   Current HIV/AIDS Reports

Lactobacillus GG treatment ameliorates alcohol-induced intestinal oxidative stress, gut leakiness, and liver injury in a rat model of alcoholic steatohepatitis

(2009) Christopher B. Forsyth et al.   ALCOHOL

Working and Episodic Memory in HIV Infection, Alcoholism, and Their Comorbidity: Baseline and 1-Year Follow-Up Examinations

(2009) Rosemary Fama et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Intestinal Dysbiosis: A Possible Mechanism of Alcohol-Induced Endotoxemia and Alcoholic Steatohepatitis in Rats

(2009) Ece Mutlu et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Nitric Oxide-Mediated Intestinal Injury Is Required for Alcohol-Induced Gut Leakiness and Liver Damage

(2009) Yueming Tang et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Critical Role of TLR4 Response in the Activation of Microglia Induced by Ethanol

(2009) S. Fernandez-Lizarbe et al.   JOURNAL OF IMMUNOLOGY

The Opposite Effects of Acute and Chronic Alcohol on Lipopolysaccharide-Induced Inflammation Are Linked to IRAK-M in Human Monocytes

(2009) P. Mandrekar et al.   JOURNAL OF IMMUNOLOGY

White matter tract injury and cognitive impairment in human immunodeficiency virus–infected individuals

(2009) Assawin Gongvatana et al.   JOURNAL OF NEUROVIROLOGY

Evidence for ongoing brain injury in human immunodeficiency virus–positive patients treated with antiretroviral therapy

(2009) VA Cardenas et al.   JOURNAL OF NEUROVIROLOGY

A critical review of human endotoxin administration as an experimental paradigm of depression

(2009) Nicole DellaGioia et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

High-Density Lipoprotein Cholesterol in HIV-Infected Patients: Evidence for an Association with HIV-1 Viral Load, Antiretroviral Therapy Status, and Regimen Composition

(2008) Enrique Bernal et al.   AIDS PATIENT CARE AND STDS

Human Immunodeficiency Virus-Related Microbial Translocation and Progression of Hepatitis C

(2008) Ashwin Balagopal et al.   GASTROENTEROLOGY

Evidence that chronic alcohol exposure promotes intestinal oxidative stress, intestinal hyperpermeability and endotoxemia prior to development of alcoholic steatohepatitis in rats

(2008) Ali Keshavarzian et al.   JOURNAL OF HEPATOLOGY

Ethanol mimics ligand-mediated activation and endocytosis of IL-1RITLR4 receptors vialipid raftscaveolae in astroglial cells

(2008) Ana M. Blanco et al.   JOURNAL OF NEUROCHEMISTRY

Increased systemic and brain cytokine production and neuroinflammation by endotoxin following ethanol treatment

(2008) Liya Qin et al.   Journal of Neuroinflammation

Brain Chromatin Remodeling: A Novel Mechanism of Alcoholism

(2008) S. C. Pandey et al.   JOURNAL OF NEUROSCIENCE

Human Immunodeficiency Virus Type 1 Infection Increases the In Vivo Capacity of Peripheral Monocytes To Cross the Blood-Brain Barrier into the Brain and the In Vivo Sensitivity of the Blood-Brain Barrier to Disruption by Lipopolysaccharide

(2008) H. Wang et al.   JOURNAL OF VIROLOGY

Microbial Translocation Is Associated with Increased Monocyte Activation and Dementia in AIDS Patients

(2008) Petronela Ancuta et al.   PLoS One

Increased MCP-1 and microglia in various regions of the human alcoholic brain

(2007) Jun He et al.   EXPERIMENTAL NEUROLOGY

Lipid rafts regulate ethanol-induced activation of TLR4 signaling in murine macrophages

(2007) Sara Fernandez-Lizarbe et al.   MOLECULAR IMMUNOLOGY