Botulinum Neurotoxin Serotype A Recognizes Its Protein Receptor SV2 by a Different Mechanism than Botulinum Neurotoxin B Synaptotagmin

The long journey of botulinum neurotoxins into the synapse

(2015) Andreas Rummel   TOXICON

Botulinum Neurotoxins: Qualitative and Quantitative Analysis Using the Mouse Phrenic Nerve Hemidiaphragm Assay (MPN)

(2015) Hans Bigalke et al.   Toxins

Generation and Characterization of Six Recombinant Botulinum Neurotoxins as Reference Material to Serve in an International Proficiency Test

(2015) Jasmin Weisemann et al.   Toxins

Identification of the synaptic vesicle glycoprotein 2 receptor binding site in botulinum neurotoxin A

(2014) Jasmin Strotmeier et al.   FEBS LETTERS

Botulinum neurotoxins: new questions arising from structural biology

(2014) Richard A. Kammerer et al.   TRENDS IN BIOCHEMICAL SCIENCES

Identification of the SV2 protein receptor-binding site of botulinum neurotoxin type E

(2013) Stefan Mahrhold et al.   BIOCHEMICAL JOURNAL

Structural basis for recognition of synaptic vesicle protein 2C by botulinum neurotoxin A

(2013) Roger M. Benoit et al.   NATURE

Crystal Structures of Botulinum Neurotoxin DC in Complex with Its Protein Receptors Synaptotagmin I and II

(2013) Ronnie Per-Arne Berntsson et al.   STRUCTURE

Structure of dual receptor binding to botulinum neurotoxin B

(2013) Ronnie P-A. Berntsson et al.   Nature Communications

Identification of Fibroblast Growth Factor Receptor 3 (FGFR3) as a Protein Receptor for Botulinum Neurotoxin Serotype A (BoNT/A)

(2013) Birgitte P. S. Jacky et al.   PLoS Pathogens

Human synaptotagmin-II is not a high affinity receptor for botulinum neurotoxin B and G: Increased therapeutic dosage and immunogenicity

(2012) Jasmin Strotmeier et al.   FEBS LETTERS

Botulinum neurotoxin D-C uses synaptotagmin I and II as receptors, and human synaptotagmin II is not an effective receptor for type B, D-C and G toxins

(2012) Lisheng Peng et al.   JOURNAL OF CELL SCIENCE

Unique Ganglioside Recognition Strategies for Clostridial Neurotoxins

(2011) Marc A. Benson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Botulinum Neurotoxin D Uses Synaptic Vesicle Protein SV2 and Gangliosides as Receptors

(2011) Lisheng Peng et al.   PLoS Pathogens

Glycosylated SV2 and Gangliosides as Dual Receptors for Botulinum Neurotoxin Serotype F

(2009) Zhuji Fu et al.   BIOCHEMISTRY

Botulinum neurotoxins C, E and F bind gangliosides via a conserved binding site prior to stimulation-dependent uptake with botulinum neurotoxin F utilising the three isoforms of SV2 as second receptor

(2009) Andreas Rummel et al.   JOURNAL OF NEUROCHEMISTRY

Cell entry strategy of clostridial neurotoxins

(2009) Thomas Binz et al.   JOURNAL OF NEUROCHEMISTRY

Solution Structure and Refolding of theMycobacterium tuberculosisPentapeptide Repeat Protein MfpA

(2008) Sergei Khrapunov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glycosylated SV2A and SV2B Mediate the Entry of Botulinum Neurotoxin E into Neurons

(2008) Min Dong et al.   MOLECULAR BIOLOGY OF THE CELL

Crystal Structure of Botulinum Neurotoxin Type A in Complex with the Cell Surface Co-Receptor GT1b—Insight into the Toxin–Neuron Interaction

(2008) Pål Stenmark et al.   PLoS Pathogens

Botulinum Neurotoxin Devoid of Receptor Binding Domain Translocates Active Protease

(2008) Audrey Fischer et al.   PLoS Pathogens