Concise Review: Organoids Are a Powerful Tool for the Study of Liver Disease and Personalized Treatment Design in Humans and Animals

A concise review of non-alcoholic fatty liver disease

(2015) Nwe Ni Than et al.   ATHEROSCLEROSIS

Long-Term Culture of Genome-Stable Bipotent Stem Cells from Adult Human Liver

(2015) Meritxell Huch et al.   CELL

Prospective Derivation of a Living Organoid Biobank of Colorectal Cancer Patients

(2015) Marc van de Wetering et al.   CELL

Organoid Models of Human and Mouse Ductal Pancreatic Cancer

(2015) Sylvia F. Boj et al.   CELL

Potential Epigenetic Mechanism in Non-Alcoholic Fatty Liver Disease

(2015) Chao Sun et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A bioassay using intestinal organoids to measure CFTR modulators in human plasma

(2015) R. Dekkers et al.   Journal of Cystic Fibrosis

Hepatic progenitor cells of biliary origin with liver repopulation capacity

(2015) Wei-Yu Lu et al.   NATURE CELL BIOLOGY

Advances in experimental systems to study hepatitis C virus in vitro and in vivo

(2015) Maria Teresa Catanese et al.   VIROLOGY

Disease Modeling and Gene Therapy of Copper Storage Disease in Canine Hepatic Organoids

(2015) Sathidpak Nantasanti et al.   Stem Cell Reports

Pluripotent stem cell-derived hepatocyte-like cells

(2014) R.E. Schwartz et al.   BIOTECHNOLOGY ADVANCES

The importance of comparative oncology in translational medicine

(2014) Federica Riccardo et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Cystic fibrosis: Toward personalized therapies

(2014) Pauline T. Ikpa et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Abnormalities in human pluripotent cells due to reprogramming mechanisms

(2014) Hong Ma et al.   NATURE

Complete replication of hepatitis B virus and hepatitis C virus in a newly developed hepatoma cell line

(2014) Darong Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Assembly of Human Organs from Stem Cells to Study Liver Disease

(2013) Kan Handa et al.   AMERICAN JOURNAL OF PATHOLOGY

Liver Extracellular Matrix Providing Dual Functions of Two-Dimensional Substrate Coating and Three-Dimensional Injectable Hydrogel Platform for Liver Tissue Engineering

(2013) Jung Seung Lee et al.   BIOMACROMOLECULES

Functional Repair of CFTR by CRISPR/Cas9 in Intestinal Stem Cell Organoids of Cystic Fibrosis Patients

(2013) Gerald Schwank et al.   Cell Stem Cell

Unlimited in vitro expansion of adult bi-potent pancreas progenitors through the Lgr5/R-spondin axis

(2013) Meritxell Huch et al.   EMBO JOURNAL

In vitro expansion of single Lgr5+ liver stem cells induced by Wnt-driven regeneration

(2013) Meritxell Huch et al.   NATURE

A functional CFTR assay using primary cystic fibrosis intestinal organoids

(2013) Johanna F Dekkers et al.   NATURE MEDICINE

Adult-Derived Human Liver Progenitor Cells in Long-Term Culture Maintain Appropriate Gatekeeper Mechanisms against Transformation

(2012) Isabelle Scheers et al.   CELL TRANSPLANTATION

Productive Hepatitis C Virus Infection of Stem Cell-Derived Hepatocytes Reveals a Critical Transition to Viral Permissiveness during Differentiation

(2012) Xianfang Wu et al.   PLoS Pathogens

Nutrigenomics of hepatic steatosis in a feline model: effect of monosodium glutamate, fructose, and Trans-fat feeding

(2011) Kate S. Collison et al.   Genes and Nutrition

Expression of paramyxovirus V proteins promotes replication and spread of hepatitis C virus in cultures of primary human fetal liver cells

(2011) Linda Andrus et al.   HEPATOLOGY

Feline cholangitis: a necropsy study of 44 cats (1986–2008)

(2011) Julie E. Callahan Clark et al.   JOURNAL OF FELINE MEDICINE AND SURGERY

Controlled gene expression in primary Lgr5 organoid cultures

(2011) Bon-Kyoung Koo et al.   NATURE METHODS

Understanding the Host Genetics of Chronic Hepatitis B and C

(2011) Mark Thursz et al.   SEMINARS IN LIVER DISEASE

Hepatitis C virus entry into hepatocytes: Molecular mechanisms and targets for antiviral therapies

(2010) Mirjam B. Zeisel et al.   JOURNAL OF HEPATOLOGY

Differential effect of oleic and palmitic acid on lipid accumulation and apoptosis in cultured hepatocytes

(2009) Matteo Ricchi et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Human hepatocyte transplantation: state of the art

(2009) E. Fitzpatrick et al.   JOURNAL OF INTERNAL MEDICINE

Hepatic Lipidosis in Cats

(2009) P. Jane Armstrong et al.   VETERINARY CLINICS OF NORTH AMERICA-SMALL ANIMAL PRACTICE

Characterisation of the hepatic progenitor cell compartment in normal liver and in hepatitis: An immunohistochemical comparison between dog and man

(2009) J. IJzer et al.   VETERINARY JOURNAL

In Vitro Differentiation of Embryonic and Adult Stem Cells into Hepatocytes: State of the Art

(2008) Sarah Snykers et al.   STEM CELLS

In Vitro Differentiation of Liver Progenitor Cells Derived from Healthy Dog Livers

(2008) Brigitte Arends et al.   STEM CELLS AND DEVELOPMENT