A Subset of Latency-Reversing Agents Expose HIV-Infected Resting CD4+ T-Cells to Recognition by Cytotoxic T-Lymphocytes
Published 2016 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
A Subset of Latency-Reversing Agents Expose HIV-Infected Resting CD4+ T-Cells to Recognition by Cytotoxic T-Lymphocytes
Authors
Keywords
T cells, Cytotoxic T cells, HIV, Flow cytometry, Viral persistence and latency, Cell staining, Enzyme-linked immunoassays, HIV infections
Journal
PLoS Pathogens
Volume 12, Issue 4, Pages e1005545
Publisher
Public Library of Science (PLoS)
Online
2016-04-16
DOI
10.1371/journal.ppat.1005545
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Ex vivo analysis identifies effective HIV-1 latency–reversing drug combinations
- (2015) Gregory M. Laird et al. JOURNAL OF CLINICAL INVESTIGATION
- Expanded Cytotoxic T-cell Lymphocytes Target the Latent HIV Reservoir
- (2015) Julia A. Sung et al. JOURNAL OF INFECTIOUS DISEASES
- In VivoActivation of Human NK Cells by Treatment with an Interleukin-15 Superagonist Potently Inhibits AcuteIn VivoHIV-1 Infection in Humanized Mice
- (2015) Kieran Seay et al. JOURNAL OF VIROLOGY
- Broad CTL response is required to clear latent HIV-1 due to dominance of escape mutations
- (2015) Kai Deng et al. NATURE
- IL-2: The First Effective Immunotherapy for Human Cancer
- (2014) S. A. Rosenberg JOURNAL OF IMMUNOLOGY
- New ex vivo approaches distinguish effective and ineffective single agents for reversing HIV-1 latency in vivo
- (2014) C Korin Bullen et al. NATURE MEDICINE
- Intravesical ALT-803 and BCG Treatment Reduces Tumor Burden in a Carcinogen Induced Bladder Cancer Rat Model; a Role for Cytokine Production and NK Cell Expansion
- (2014) Evan Gomes-Giacoia et al. PLoS One
- Quantification of HIV-1 latency reversal in resting CD4+ T cells from patients on suppressive antiretroviral therapy
- (2014) A. R. Cillo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Psychosocial, mental health, and behavioral issues of aging with HIV
- (2014) Sergio Rueda et al. Current Opinion in HIV and AIDS
- Activation of HIV Transcription with Short-Course Vorinostat in HIV-Infected Patients on Suppressive Antiretroviral Therapy
- (2014) Julian H. Elliott et al. PLoS Pathogens
- Histone Deacetylase Inhibitors Impair the Elimination of HIV-Infected Cells by Cytotoxic T-Lymphocytes
- (2014) Richard Brad Jones et al. PLoS Pathogens
- Histone Deacetylase Inhibitor Romidepsin Induces HIV Expression in CD4 T Cells from Patients on Suppressive Antiretroviral Therapy at Concentrations Achieved by Clinical Dosing
- (2014) Datsen George Wei et al. PLoS Pathogens
- Dynamics of HIV Latency and Reactivation in a Primary CD4+ T Cell Model
- (2014) Pejman Mohammadi et al. PLoS Pathogens
- Efficacy and Mechanism-of-Action of a Novel Superagonist Interleukin-15: Interleukin-15 Receptor Su/Fc Fusion Complex in Syngeneic Murine Models of Multiple Myeloma
- (2013) W. Xu et al. CANCER RESEARCH
- Replication-Competent Noninduced Proviruses in the Latent Reservoir Increase Barrier to HIV-1 Cure
- (2013) Ya-Chi Ho et al. CELL
- Gag-Positive Reservoir Cells Are Susceptible to HIV-Specific Cytotoxic T Lymphocyte Mediated Clearance In Vitro and Can Be Detected In Vivo
- (2013) Erin H. Graf et al. PLoS One
- HIV infection and depression
- (2013) Stylianos Arseniou et al. PSYCHIATRY AND CLINICAL NEUROSCIENCES
- Reactivation of latent HIV-1 in central memory CD4+ T cells through TLR-1/2 stimulation
- (2013) Camille L Novis et al. Retrovirology
- Comparison of HDAC inhibitors in clinical development
- (2013) Thomas Aagaard Rasmussen et al. Human Vaccines & Immunotherapeutics
- The IL-15-based superagonist ALT-803 promotes the antigen-independent conversion of memory CD8+T cells into innate-like effector cells with antitumor activity
- (2013) Hing C Wong et al. OncoImmunology
- Stimulation of HIV-1-Specific Cytolytic T Lymphocytes Facilitates Elimination of Latent Viral Reservoir after Virus Reactivation
- (2012) Liang Shan et al. IMMUNITY
- HERV-K–specific T cells eliminate diverse HIV-1/2 and SIV primary isolates
- (2012) R. Brad Jones et al. JOURNAL OF CLINICAL INVESTIGATION
- Effect of Histone Deacetylase Inhibitors on HIV Production in Latently Infected, Resting CD4+ T Cells From Infected Individuals Receiving Effective Antiretroviral Therapy
- (2012) J. Blazkova et al. JOURNAL OF INFECTIOUS DISEASES
- Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapy
- (2012) N. M. Archin et al. NATURE
- Shock and kill
- (2012) Steven G. Deeks NATURE
- Directly Infected Resting CD4+T Cells Can Produce HIV Gag without Spreading Infection in a Model of HIV Latency
- (2012) Matthew J. Pace et al. PLoS Pathogens
- IL-15:IL-15 receptor alpha superagonist complex: High-level co-expression in recombinant mammalian cells, purification and characterization
- (2011) Kai-ping Han et al. CYTOKINE
- Expression and reactivation of HIV in a chemokine induced model of HIV latency in primary resting CD4+ T cells
- (2011) Suha Saleh et al. Retrovirology
- TLR1/2 Activation during Heterologous Prime-Boost Vaccination (DNA-MVA) Enhances CD8+ T Cell Responses Providing Protection against Leishmania (Viannia)
- (2011) Asha Jayakumar et al. PLoS Neglected Tropical Diseases
- Homeostatic Proliferation Fails to Efficiently Reactivate HIV-1 Latently Infected Central Memory CD4+ T Cells
- (2011) Alberto Bosque et al. PLoS Pathogens
- Therapeutic cell engineering with surface-conjugated synthetic nanoparticles
- (2010) Matthias T Stephan et al. NATURE MEDICINE
- CD8 Cells of Patients with Diffuse Cutaneous Leishmaniasis Display Functional Exhaustion: The Latter Is Reversed, In Vitro, by TLR2 Agonists
- (2010) Joselín Hernández-Ruiz et al. PLoS Neglected Tropical Diseases
- Expression of Latent HIV Induced by the Potent HDAC Inhibitor Suberoylanilide Hydroxamic Acid
- (2009) Nancie M. Archin et al. AIDS RESEARCH AND HUMAN RETROVIRUSES
- Long-term outcome of EBV-specific T-cell infusions to prevent or treat EBV-related lymphoproliferative disease in transplant recipients
- (2009) H. E. Heslop et al. BLOOD
- Suberoylanilide Hydroxamic Acid Reactivates HIV from Latently Infected Cells
- (2009) Xavier Contreras et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Novel Human Interleukin-15 Agonists
- (2009) X. Zhu et al. JOURNAL OF IMMUNOLOGY
- Expression and Function of TLR2 on CD4 Versus CD8 T Cells
- (2009) Sun-Mi Lee et al. Immune Network
- Engagement of Toll-like receptor-2 on cytotoxic T-lymphocytes occurs in vivo and augments antitumor activity
- (2008) Nicole Asprodites et al. FASEB JOURNAL
- Hexamethylbisacetamide and Disruption of Human Immunodeficiency Virus Type 1 Latency in CD4+T Cells
- (2008) Shailesh K. Choudhary et al. JOURNAL OF INFECTIOUS DISEASES
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started