A Computationally Designed Hemagglutinin Stem-Binding Protein Provides In Vivo Protection from Influenza Independent of a Host Immune Response

Direct Administration in the Respiratory Tract Improves Efficacy of Broadly Neutralizing Anti-Influenza Virus Monoclonal Antibodies

(2015) Victor H. Leyva-Grado et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Antibody-Based Strategies to Prevent and Treat Influenza

(2015) Zachary Shriver et al.   Frontiers in Immunology

Broadly Neutralizing Anti-HIV-1 Antibodies Require Fc Effector Functions for In Vivo Activity

(2014) Stylianos Bournazos et al.   CELL

Broadly Neutralizing Influenza Hemagglutinin Stem-Specific Antibody CR8020 Targets Residues that Are Prone to Escape due to Host Selection Pressure

(2014) Kannan Tharakaraman et al.   Cell Host & Microbe

Antiviral combinations for severe influenza

(2014) Jake Dunning et al.   LANCET INFECTIOUS DISEASES

Broadly neutralizing hemagglutinin stalk–specific antibodies require FcγR interactions for protection against influenza virus in vivo

(2014) David J DiLillo et al.   NATURE MEDICINE

The co-pathogenesis of influenza viruses with bacteria in the lung

(2014) Jonathan A. McCullers   NATURE REVIEWS MICROBIOLOGY

Prevention of influenza by targeting host receptors using engineered proteins

(2014) H. Connaris et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evaluation of neutralizing efficacy of monoclonal antibodies specific for 2009 pandemic H1N1 influenza A virus in vitro and in vivo

(2013) Jianjun Chen et al.   ARCHIVES OF VIROLOGY

Influenza virus A(H1N1)pdm09 hemagglutinin polymorphism and associated disease in southern Germany during the 2010/11 influenza season

(2013) Valeria Falcone et al.   ARCHIVES OF VIROLOGY

The Neuraminidase Inhibitor Oseltamivir Is Effective Against A/Anhui/1/2013 (H7N9) Influenza Virus in a Mouse Model of Acute Respiratory Distress Syndrome

(2013) T. Baranovich et al.   JOURNAL OF INFECTIOUS DISEASES

New Small Molecule Entry Inhibitors Targeting Hemagglutinin-Mediated Influenza A Virus Fusion

(2013) A. Basu et al.   JOURNAL OF VIROLOGY

Early Host Responses of Seasonal and Pandemic Influenza A Viruses in Primary Well-Differentiated Human Lung Epithelial Cells

(2013) Rachael L. Gerlach et al.   PLoS One

Identifying the Interaction Between Influenza and Pneumococcal Pneumonia Using Incidence Data

(2013) S. Shrestha et al.   Science Translational Medicine

Influenza virus hemagglutinin stalk-based antibodies and vaccines

(2013) Florian Krammer et al.   Current Opinion in Virology

Comparison of ribavirin and oseltamivir in reducing mortality and lung injury in mice infected with mouse adapted A/California/04/2009 (H1N1)

(2012) Sotirios G. Zarogiannis et al.   LIFE SCIENCES

Optimization of affinity, specificity and function of designed influenza inhibitors using deep sequencing

(2012) Timothy A Whitehead et al.   NATURE BIOTECHNOLOGY

A fundamental protein property, thermodynamic stability, revealed solely from large-scale measurements of protein function

(2012) C. L. Araya et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Broadly neutralizing antibodies against influenza virus and prospects for universal therapies

(2012) Damian C Ekiert et al.   Current Opinion in Virology

High-throughput protein production and purification at the Seattle Structural Genomics Center for Infectious Disease

(2011) Cassie M. Bryan et al.   Acta Crystallographica Section F-Structural Biology and Crystallization Communications

Immobilized metal-affinity chromatography protein-recovery screening is predictive of crystallographic structure success

(2011) Ryan Choi et al.   Acta Crystallographica Section F-Structural Biology and Crystallization Communications

Enrich: software for analysis of protein function by enrichment and depletion of variants

(2011) Douglas M. Fowler et al.   BIOINFORMATICS

Suppression of cytokine storm with a sphingosine analog provides protection against pathogenic influenza virus

(2011) K. B. Walsh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Computational Design of Proteins Targeting the Conserved Stem Region of Influenza Hemagglutinin

(2011) S. J. Fleishman et al.   SCIENCE

Influenza Drug Resistance

(2011) Andrés Pizzorno et al.   SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE

Antivirals and resistance: influenza virus

(2011) Michael G Ison   Current Opinion in Virology

In vivo ribavirin activity against severe pandemic H1N1 influenza A/Mexico/4108/2009

(2010) T. Rowe et al.   JOURNAL OF GENERAL VIROLOGY

A clustering approach to multireference alignment of single-particle projections in electron microscopy

(2010) C.O.S. Sorzano et al.   JOURNAL OF STRUCTURAL BIOLOGY

MyD88 Signaling Is Indispensable for Primary Influenza A Virus Infection but Dispensable for Secondary Infection

(2010) S.-U. Seo et al.   JOURNAL OF VIROLOGY

Adaptation of Pandemic H1N1 Influenza Viruses in Mice

(2010) N. A. Ilyushina et al.   JOURNAL OF VIROLOGY

Influenza Vaccines for the Future

(2010) Linda C. Lambert et al.   NEW ENGLAND JOURNAL OF MEDICINE

The 2009 A (H1N1) influenza virus pandemic: A review

(2010) Marc P. Girard et al.   VACCINE

Effects of the Combination of Favipiravir (T-705) and Oseltamivir on Influenza A Virus Infections in Mice

(2009) D. F. Smee et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Inflammasome recognition of influenza virus is essential for adaptive immune responses

(2009) Takeshi Ichinohe et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Appion: An integrated, database-driven pipeline to facilitate EM image processing

(2009) Gabriel C. Lander et al.   JOURNAL OF STRUCTURAL BIOLOGY

DoG Picker and TiltPicker: Software tools to facilitate particle selection in single particle electron microscopy

(2009) N.R. Voss et al.   JOURNAL OF STRUCTURAL BIOLOGY

Enzymatic assembly of DNA molecules up to several hundred kilobases

(2009) Daniel G Gibson et al.   NATURE METHODS