MTOR-Driven Metabolic Reprogramming Regulates Legionella pneumophila Intracellular Niche Homeostasis

Autophagy Evasion and Endoplasmic Reticulum Subversion: The Yin and Yang ofLegionellaIntracellular Infection

(2016) Racquel Kim Sherwood et al.   Annual Review of Microbiology

The Mechanistic Target of Rapamycin: The Grand ConducTOR of Metabolism and Aging

(2016) Brian K. Kennedy et al.   Cell Metabolism

The Type IVB secretion system: an enigmatic chimera

(2016) Tomoko Kubori et al.   CURRENT OPINION IN MICROBIOLOGY

Rapamycin: An InhibiTOR of Aging Emerges From the Soil of Easter Island

(2016) Sebastian I. Arriola Apelo et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Pathway analysis using13C-glycerol and other carbon tracers reveals a bipartite metabolism ofLegionella pneumophila

(2016) Ina Häuslein et al.   MOLECULAR MICROBIOLOGY

Genomic analysis of 38 Legionella species identifies large and diverse effector repertoires

(2016) David Burstein et al.   NATURE GENETICS

IL-1R signaling enables bystander cells to overcome bacterial blockade of host protein synthesis

(2015) Alan M. Copenhaver et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MavN is aLegionella pneumophilavacuole-associated protein required for efficient iron acquisition during intracellular growth

(2015) Dervla T. Isaac et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intranuclear bacteria: inside the cellular control center of eukaryotes

(2015) Frederik Schulz et al.   TRENDS IN CELL BIOLOGY

Mevalonate Pathway Regulates Cell Size Homeostasis and Proteostasis through Autophagy

(2015) Teemu P. Miettinen et al.   Cell Reports

The emerging role of mTOR signalling in antibacterial immunity

(2014) Mena Abdel-Nour et al.   IMMUNOLOGY AND CELL BIOLOGY

Where is mTOR and what is it doing there?

(2014) Charles Betz et al.   JOURNAL OF CELL BIOLOGY

Cytoplasmic access by intracellular bacterial pathogens

(2014) Jennifer Fredlund et al.   TRENDS IN MICROBIOLOGY

Genome-Wide Analysis of SREBP1 Activity around the Clock Reveals Its Combined Dependency on Nutrient and Circadian Signals

(2014) Federica Gilardi et al.   PLoS Genetics

The Frustrated Host Response to Legionella pneumophila Is Bypassed by MyD88-Dependent Translation of Pro-inflammatory Cytokines

(2014) Seblewongel Asrat et al.   PLoS Pathogens

The role of ‘eat-me’ signals and autophagy cargo receptors in innate immunity

(2013) Keith B. Boyle et al.   CURRENT OPINION IN MICROBIOLOGY

Maintenance of vacuole integrity by bacterial pathogens

(2013) Elizabeth A. Creasey et al.   CURRENT OPINION IN MICROBIOLOGY

The multifaceted role of mTORC1 in the control of lipid metabolism

(2013) Stéphane J H Ricoult et al.   EMBO REPORTS

Pathogen signatures activate a ubiquitination pathway that modulates the function of the metabolic checkpoint kinase mTOR

(2013) Stanimir S Ivanov et al.   NATURE IMMUNOLOGY

mTORC1 Phosphorylation Sites Encode Their Sensitivity to Starvation and Rapamycin

(2013) S. A. Kang et al.   SCIENCE

mTOR Signaling in Growth Control and Disease

(2012) Mathieu Laplante et al.   CELL

Amino Acid Starvation Induced by Invasive Bacterial Pathogens Triggers an Innate Host Defense Program

(2012) Ivan Tattoli et al.   Cell Host & Microbe

TOR complex 2 (TORC2) in Dictyostelium suppresses phagocytic nutrient capture independently of TORC1-mediated nutrient sensing

(2012) D. Rosel et al.   JOURNAL OF CELL SCIENCE

The protein SdhA maintains the integrity of the Legionella-containing vacuole

(2012) E. A. Creasey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Aggravating Genetic Interactions Allow a Solution to Redundancy in a Bacterial Pathogen

(2012) T. J. O'Connor et al.   SCIENCE

The Legionella Effector RavZ Inhibits Host Autophagy Through Irreversible Atg8 Deconjugation

(2012) A. Choy et al.   SCIENCE

Minimization of the Legionella pneumophila genome reveals chromosomal regions involved in host range expansion

(2011) T. J. O'Connor et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The mammalian target of rapamycin regulates cholesterol biosynthetic gene expression and exhibits a rapamycin-resistant transcriptional profile

(2011) B. T. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SREBPs: metabolic integrators in physiology and metabolism

(2011) Tae-Il Jeon et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Modulation of Host Cell Function byLegionella pneumophilaType IV Effectors

(2010) Andree Hubber et al.   Annual Review of Cell and Developmental Biology

Pore Formation Triggered by Legionella spp. Is an Nlrc4 Inflammasome-Dependent Host Cell Response That Precedes Pyroptosis

(2010) T. N. Silveira et al.   INFECTION AND IMMUNITY

Activation of a Metabolic Gene Regulatory Network Downstream of mTOR Complex 1

(2010) Katrin Düvel et al.   MOLECULAR CELL

Coordination of Lipid Metabolism in Membrane Biogenesis

(2009) Axel Nohturfft et al.   Annual Review of Cell and Developmental Biology

Leading a Sheltered Life: Intracellular Pathogens and Maintenance of Vacuolar Compartments

(2009) Yadunanda Kumar et al.   Cell Host & Microbe

A Small Molecule That Blocks Fat Synthesis By Inhibiting the Activation of SREBP

(2009) Shinji Kamisuki et al.   CHEMISTRY & BIOLOGY

An Emerging Role of mTOR in Lipid Biosynthesis

(2009) Mathieu Laplante et al.   CURRENT BIOLOGY

Identification of Host Cytosolic Sensors and Bacterial Factors Regulating the Type I Interferon Response to Legionella pneumophila

(2009) Kathryn M. Monroe et al.   PLoS Pathogens

SREBP Activity Is Regulated by mTORC1 and Contributes to Akt-Dependent Cell Growth

(2008) Thomas Porstmann et al.   Cell Metabolism

Host cell processes that influence the intracellular survival of Legionella pneumophila

(2008) Sunny Shin et al.   CELLULAR MICROBIOLOGY

Modulation of ubiquitin dynamics and suppression of DALIS formation by theLegionella pneumophilaDot/Icm system

(2008) Stanimir S. Ivanov et al.   CELLULAR MICROBIOLOGY

The TSC-mTOR Signaling Pathway Regulates the Innate Inflammatory Response

(2008) Thomas Weichhart et al.   IMMUNITY

The manifold phospholipases A of Legionella pneumophila – Identification, export, regulation, and their link to bacterial virulence

(2008) Sangeeta Banerji et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Toll-like receptor–mediated induction of type I interferon in plasmacytoid dendritic cells requires the rapamycin-sensitive PI(3)K-mTOR-p70S6K pathway

(2008) Weiping Cao et al.   NATURE IMMUNOLOGY

The TORrid affairs of viruses: effects of mammalian DNA viruses on the PI3K–Akt–mTOR signalling pathway

(2008) Nicholas J. Buchkovich et al.   NATURE REVIEWS MICROBIOLOGY

The Legionella pneumophila replication vacuole: making a cosy niche inside host cells

(2008) Ralph R. Isberg et al.   NATURE REVIEWS MICROBIOLOGY